Positive tests for people with suspected
Zika infection increased from 14 percent in February to 64 percent in June in Puerto Rico.
Not exact matches
The authors also looked at a temporal association between
Zika infection and an
increase in cases of Guillain - Barré syndrome.
Nielsen and her colleagues have shown that, in a small sample of 125 infected pregnant women,
Zika infection in the first trimester was linked to a 10 to 15 per cent
increase in the likelihood of miscarriage.
Analysis of geospatial data and socioeconomic status demonstrated a connection between the likelihood of
Zika infection and
increased poverty.
«The
increased number of newborns with microcephaly observed during the
Zika outbreak in Brazil is linked to
Zika infection of the mother during early pregnancy,» explains Drexler.
Mice that didn't have prior
Zika infections developed clinical symptoms and sharply
increased levels of
Zika virus in their blood, which spread to fetal tissues.
These results collectively suggest that neural stem cells need MSI1 to generate enough neurons for normal brain size, but the presence of MSI1 also
increases the vulnerability of these cells to
Zika infection, leading to the death of the population which ultimately results in microcephaly.
Our study suggests that the immune response to an early
infection, HSV - 2, may be the additional factor that
increases the risk for severity of
Zika virus - induced disease,» said Dr. Gil Mor, senior author of the American Journal of Reproductive Immunology study.
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Although
Zika infections typically cause only mild symptoms, concerns have been heightened by Brazil's reports of an unusual
increase in microcephaly — unusually small head size — in babies born in areas where the virus is circulating.
The study, led by the University of Leeds, found that inflammation where the insect has bitten not only helps a virus such as
Zika or dengue establish an
infection in the body more quickly, but that it also helps it to spread around the body,
increasing the likelihood of severe illness.
«Those who have argued for the postponement of the Rio Olympics due to the risk posed by the ongoing
Zika virus epidemic base their argument on two principal assumptions: 1) that the half a million visitors to Brazil will generate a substantial
increase in exported
Zika infections, and 2) that some of these exports will seed outbreaks in other parts of the world.
While
Zika infections don't appear to be dangerous to most people, there is
increasing concern over its suspected link to a surge in babies born with brain defects and abnormally small heads, particularly in Brazil and Colombia.
It would be interesting to assess whether the antibodies induced by these
Zika vaccine types
increase infection by dengue viruses.
The birth prevalence of neonatal microcephaly and other central nervous system malformations greatly
increased between 2015 and mid-2016 in Brazil.1 - 3 Several reports1,2,4 - 6 suggested an association between these findings and
Zika virus (ZIKV)
infection during outbreaks in Brazil and French Polynesia.
Researchers have shown that one
infection with
Zika virus protects against future
infection, though pregnancy may drastically
increase the time the virus stays in the body.
Contracted through the bite of an infected mosquito or through sexual or other modes of transmission,
Zika virus (ZIKV)
infection can be prenatally passed from mother to fetus.1 The virus was first identified in the region of the Americas in early 2015, when local transmission was reported in Brazil.2 Six months later, a notable
increase in the number of infants with congenital microcephaly was observed in northeast Brazil.3, 4 Clinical, epidemiologic, and laboratory evidence led investigators to conclude that intrauterine ZIKV
infection was a cause of microcephaly and serious brain anomalies.5 - 7 However, as with other newly recognized teratogens, these features likely represent a portion of a broader spectrum.
The bad news, Dudley's team now finds, is that pregnancy seems to
increase how long a
Zika infection lingers in the body.
Interestingly, they found that
infection with the Asian strain of
Zika virus triggered a stronger innate immune system response than the African strain, including
increased expression of the gene TP53.
While they aren't sure yet, the researchers note that the
Zika virus resembles some
infections that can
increase the risk for mental illness later in life, like schizophrenia, autism, and bipolar disorder.
«Whether contact with highly infectious bodily fluids from patients with severe [
Zika]
infection poses an
increased risk of transmission is an important question that requires further research,» the University of Utah doctors concluded.