Sentences with phrase «zika infects human»

For instance, the way Zika infects human cells and hijacks their machinery to copy itself many times has proved elusive.
In a study published Tuesday, lead author and professor of medicine Dr. Michael Diamond explained that by infecting these manipulated mice, the researchers were able to mimic how Zika infects humans.

Not exact matches

The Zika virus is most commonly transmitted in humans as the result of a bite from an infected mosquito or from an infected human to another human.
Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).
Benzoquinoline was also effective against vesicular stomatitis virus from the rhabdovirus family, which can infect insects, cattle, horses and pigs, and Zika virus, which is spread to humans by mosquitoes.
Human placental cell line Jeg - 3 can be readily infected by a circulating strain of Zika virus (left panel) and completely protected by treatment with nanchangmycin (right panel).
Confocal microscopy of human neural stem cell culture infected with Zika virus (red).
The team can not yet say if similar signaling happens in human fetuses infected with Zika.
The two reports also showed that Zika virus infected and damaged neuronal stem cells harvested from mice and humans.
Pregnant mice were infected with Zika virus early in pregnancy (corresponding to mid — first trimester in humans).
The researchers tested that idea by infecting newborn mice (which developmentally resemble a human fetus) with different lab - made versions of Zika.
That's consistent with earlier in vitro findings that Zika can infect and damage human neural precursor cells.
O'Connor points out that Zika - infected monkeys do not perfectly reflect humans, either, and he sees the various models as complementary.
It's very unlikely that she was infected by a bite by a mosquito that first bit her husband; the three tropical Aedes mosquito species known to transmit Zika don't live in northern Colorado, and moreover, the virus has to complete a 2 - week life cycle within the insect before it can infect the next human; Foy's wife fell ill just 9 days after his return.
Pregnant mice were infected vaginally with Zika at one of two times — one corresponding to mid first trimester in humans, the other to late first trimester.
Monkeys are naturally infected with Zika virus and are far closer to humans in many ways, and at least a half - dozen studies are underway.
Scientists are currently testing the bacterium as a potential foil against the master vector — the Aedes aegypti mosquitoes — that infect humans with dengue fever, Zika among other diseases.
The multinational research group utilized a model system where human retinal pigment epithelial cells were infected with Zika virus strain they isolated earlier from fetal brain [T1].
«It appears that pregnant women infected with Zika can pass the virus to babies in utero and that newborns also may be susceptible to infection,» said Diamond, also an associate director of the university's Center for Human Immunology and Immunotherapy Programs.
Like 80 % of humans infected with the Zika virus, most of the non-human primates used in this study lacked any apparent clinical symptoms.
Garcez and her colleagues at the Instituto D'Or in Rio de Janeiro in Brazil are starting experiments in which they will infect so - called cerebral organoids — tiny models of the developing human brain — with Zika virus and see whether their development is affected.
* Update, 7 December, 11:30 a.m.: This item has been updated to indicate that although Zika has been shown to infect mice, it is not clear whether it would have similar effects on pregnant animals as it may in humans.
Previous research conducted recently in Brazil and elsewhere points to increased mortality rates for human neural progenitor cells (hNPCs) infected by Zika virus, as well as growth inhibition and morphological abnormalities.
«What we show is that the Zika virus infects neuronal cells in dish that are counterparts to those that form the cortex during human brain development.»
Despite vaccines and efforts to eradicate the pesky insects, they continue to infect humans with feared diseases like Zika virus, malaria and West Nile virus.
«Zika virus infects human neural stem cells.»
The approach enabled a wide range of studies of human brain development, including implicating a new class of neural stem cell recently discovered by the lab in the evolutionary expansion of the human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly in infants infected in utero.
VIRUS VICTORY Zika virus (green) infects and kills stem cells (red) in human glioblastoma tissue, without infecting healthy brain cells.
«Mosquitoes could infect humans with Zika and chikungunya viruses at the same time: Second study links three mosquito - borne viruses — Zika, chikungunya and dengue — currently hitting Americas to severe neurological problems.»
In tests using human neural progenitor cells (NPCs)-- self - renewing, multipotent cells that generate neurons and other brain cell types — the scientists found that exposure to sofosbuvir not only rescued dying NPCs infected with the Zika virus, but restored gene expression linked to their antiviral response.
Mosquitoes are capable of carrying Zika and chikungunya viruses simultaneously and can secrete enough in their saliva to potentially infect humans with both viruses in a single bite, according to new research presented today at the 2016 Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).
Strengthening the link between Zika virus and microcephaly, scientists at UC San Francisco have discovered that a protein the virus uses to infect skin cells and cause a rash is present also in stem cells of the developing human brain and retina.
Concord, NH — The New Hampshire Department of Health and Human Services (DHHS) is announcing the first confirmed case of a New Hampshire resident infected with Zika virus.
«However, these new findings strongly suggest that testes function in human men infected with Zika should be closely investigated so that we can try and establish whether or not Zika poses a new threat to male reproductive function.»
To determine whether the Zika virus caused this, a number of independent teams of researchers — including two in Brazil and one at the University of California, San Diego — created brain organoids from healthy human cells and infected some of them with the Zika virus.
«It certainly doesn't take much for a virus that is perfectly adapted to infect humans to spread provided the conditions are ideal — and in the case of Zika it found a population that had never seen the virus before and so had no immunity to it, and also a bountiful supply of the insect that it needs to spread.
The Dallas County Health and Human Services Department said that an unidentified patient had become infected with the Zika virus after having sex with an individual who had returned from Venezuela, one of the Latin American countries where Zika is circulating.
One study from Indonesia performed in the 1970's found that the virus could infect livestock and bats but there are no documented cases of any of these animals transmitting Zika virus to humans.
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