Scientists say
Zika research has been hampered by a lack of funding.
UNC School of Medicine's Aravinda de Silva, PhD, who is currently working on NIH - funded Zika vaccine development and other
Zika research, is a co-author.
Wistar Team Receives Prestigious Award from National Clinical Research Forum for DNA - based
Zika Research
UNC School of Medicine researcher and public health officials to discuss
Zika research and prevention at upcoming event for students, faculty and staff at campus event.
Researchers have developed a new mouse model that could be used in
Zika research to better understand the virus and find new treatments, according to a study published in PLOS Pathogens.
This confirmation came as no surprise (scientists have been building a case against Zika for months), but it could be just the push Congress needs to authorize emergency funding for
Zika research and response.
«We need reliable laboratory diagnostics, particularly in outbreak regions like Brazil for two reasons,» explains Prof Felix Drexler, who conducts
Zika research at the Charité in Berlin.
They note that the rubella epidemic of the 1960s, when tens of thousands of babies were born with congenital rubella syndrome in the United States, can provide important lessons learned that may be directly applicable to
Zika research.
He was inspired to pursue
Zika research after a meeting at the National Institutes of Health (NIH) in June 2015, where Brazilian scientists described accounts of a rise in birth defects related to a local Zika outbreak.
Not exact matches
Many are basing their
research on prior work done on West Nile virus and dengue, which are related to
Zika.
«Our findings suggest
Zika virus should be officially added to the list of congenital infections,» said Thália Velho Barreto de Araújo of Brazil's Pernambuco University, who also worked on the
research team.
Thousands of children in Brazil have been born with shrunken heads in the past year — a birth defect that some
research suggests could result from
Zika infection.
Meanwhile in Brazil, the nation's top
research institute said that
Zika has been detected in urine and saliva, but added that there was no proof the virus could be transmitted through those fluids.
National and local health care officials said cuts in federal spending to combat the
Zika virus means fewer pregnant women will be tested and there will be less money available to develop a vaccine and
research how the disease affects fetal brains.
Even so, the city pledged $ 21 million to a three - year plan to fight
Zika that includes funding for
research and testing of mosquitoes as well as preventive measures.
Take Kellie Ann Jurado, a postdoctoral scientist in immunobiology at Yale University, who will use the funding for
research on the effects of the
Zika virus on the nervous system.
The number of
Zika cases in the Western Hemisphere has dropped this year, but the need for basic scientific and public health
research on the virus remains strong.
U.S. and Cuban scientists are planning a new round of
research collaborations as part of joint work to accelerate progress on combatting threatening mosquito - borne illnesses such as dengue fever and
Zika virus — the latest development in an ongoing collaboration between the American Association for the Advancement of Science and the Cuban Academy of Sciences.
Microbac's
research also found that bleach and peracetic acid were not as effective in killing
Zika virus when the virus is associated with blood.
The next stage of the
research will be to take a more in - depth look at how long
Zika survives on hard non-porous surfaces in the heat and how best to inactivate the virus.
Landrum and her colleagues demonstrated the effect experimentally and reported the results in a 2017 paper in the Journal of Risk
Research entitled «Culturally Antagonistic Memes and the
Zika Virus: An Experimental Test,» in which participants read a news story on
Zika public health risks that was linked to either climate change or immigration.
The scourge of
Zika prompted a similarly international
research effort, which has already resulted in potential vaccine candidates.
The
research underscores that «many viruses, including some similar to
Zika, can infect the placenta and the cells of the baby,» says George Saade, an obstetrician - gynecologist and cell biologist at the University of Texas Medical Branch at Galveston.
«Our
research is the first to study
Zika infection in a mouse model that transmits the virus in a way similar to humans,» explains Alysson R. Muotri, Ph.D., professor and director of the Stem Cell Program at UC San Diego and co-senior author of the study.
In a revolutionary first, Cancer
Research UK - funded scientists will test whether the
Zika virus can destroy brain tumour cells, potentially leading to new treatments for one of the hardest to treat cancers.
«One
research priority is to fully understand the extent of
Zika transmission, and what proportion of people in Latin America — and across the globe have been infected.
The current
Zika epidemic in Latin America is likely to burn itself out within three years, suggests new
research.
Researchers at the University of Pittsburgh and Magee - Womens
Research Institute (MWRI) have devised a cell - based model of the human placenta that could help explain how pathogens that cause birth defects, such as
Zika virus, cross from mother to unborn child.
Dr Harry Bulstrode, a Cancer
Research UK scientist at the University of Cambridge, said: «
Zika virus infection in babies and children is a major global health concern, and the focus has been to discover more about the virus to find new possible treatments.
The findings, from the Emory / Johns Hopkins / Florida State team that showed this spring that neural progenitor cells are particularly vulnerable to
Zika infection, were published in Nucleic Acid
Research.
«
Research findings may lead to promising
Zika virus drug targets.»
Dr Harry Bulstrode at the University of Cambridge has received a Cancer
Research UK Pioneer Award * to test the effect of the
Zika virus on glioblastoma, the most common and aggressive form of brain tumour.
Diagnosing
Zika viruses reliably is of major importance — for both patients and further
research on the spread of the virus.
«There are currently more questions surrounding
Zika than answers — and only through a coordinated global
research effort will we find the answers we desperately need.»
They produced
Zika virus at the Biosecurity
Research Institute and provided it to collaborators to support studies performed at several other laboratories.
Higgs noted that further
research is needed to understand how
Zika virus invades the nervous system and to determine how long and how extensively
Zika virus remains in saliva and semen.
«We had very high rates of
Zika transmission where it was very warm and very dry,» said co-author Madeleine Thomson, a senior
research scientist at the International Research Institute for Climate and Society at Columbia Uni
research scientist at the International
Research Institute for Climate and Society at Columbia Uni
Research Institute for Climate and Society at Columbia University.
For the Colombian finding, Aliota and his
research team, which includes Jorge Osorio, professor of pathobiological sciences at SVM, and two visiting doctoral students from Colombia, tested samples from 22 patients for the genetic fingerprints of
Zika, dengue and chikungunya viruses.
«Colombia is now only second to Brazil in the number of known
Zika infections,» says study lead author Matthew Aliota, a
research scientist in the UW - Madison School of Veterinary Medicine (SVM).
His
research on
Zika virus and others like it is focused on how the viruses evolve and adapt to their hosts, including mosquitoes and humans.
Editor's note: This story was updated June 6, 2017, to update the month that
Zika was confirmed in Brazil; that
Zika is thought to be in 84 countries, territories and regions; and the number of institutions involved in this
research.
Additional preclinical
research is needed before investigating whether 25HC can safely protect humans against
Zika virus infection and associated birth defects.
Research educator Tim Riedel works with a student in the University of Texas at Austin's Freshman
Research Initiative on developing a diagnostic tool for malaria,
Zika virus and more.
«Both the mosquitos that transmit
Zika and the virus itself are climate - sensitive,» said co-author Ángel Muñoz, a postdoctoral
research associate in atmospheric and oceanic science at Princeton University, in an email.
The team also looked at changes in the genetic sequence of the
Zika NS1 protein over time, noted David L. Akey, a
research scientist in Smith's lab and the study's other lead author.
«Even before
Zika, their blood samples likely had antibodies that could interact with this same spot on the envelope protein,» says Margaret R. MacDonald, a
research associate professor in Rice's lab.
A
research team based at The Rockefeller University has identified a potent new weapon against the
Zika virus in the blood of people who have been infected by it.
Garcez focuses her efforts on empowering the Brazilian public with information about the
Zika virus through numerous TV, radio, newspaper and blog interviews about her
research.
The paper, by P.P. Garcez at D'Or Institute for
Research and Education (IDOR) in Rio de Janeiro, Brazil, and colleagues was titled, «
Zika virus impairs growth in human neurospheres and brain organoids.»
During the September Congressional fight over how much to provide and whether to offset it, Mulvaney posted a Facebook update in which he questioned the relationship between
Zika and birth defects, and asked whether «we really need government - funded
research at all» given this alleged uncertainty.