Title: Adaptive feeding intervention and monitoring program for infants with congenital
Zika syndrome.
Eleven of these babies were diagnosed with microcephaly — an abnormally small head and brain — and other neurologic complications associated with
Zika syndrome, the researchers reported.
Conclusions and Relevance Although the full spectrum of adverse reproductive outcomes caused by Zika virus infection is not yet determined, a distinctive phenotype — the congenital
Zika syndrome — has emerged.
Characterizing the Pattern of Anomalies in Congenital
Zika Syndrome for Pediatric Clinicians.
The immense cost of raising Brazil's babies with congenital
Zika syndrome is straining poor families and the government that supports them.
Based on that, we recommend using the term congenital
Zika syndrome instead of microcephaly associated with Zika virus infection, which involves a spectrum of changes, including other neurological and fetal development manifestations.
«For couples wanting to get pregnant or thinking of becoming pregnant there is a different balance of risks because of the dangers of microcephaly and congenital
Zika syndrome.
Doctors have coined a new name for their disease, «congenital
Zika syndrome» — a sign of how much they have to learn.
«It's safe to say that most children with congenital
Zika syndrome will have major impairments that will not be easily treated by surgery, medication or therapy services,» Bailey said.
The impact of congenital
Zika syndrome on families will be substantial and will last a lifetime, given its severity and uncertainty about long - term outcomes for infants.
«Family impact of congenital
Zika syndrome likely to last a lifetime: Supplement in Pediatrics synthesizes research on Zika.»
What do we know and what can we expect regarding the cognitive, behavioral, and functional development of children with congenital
Zika syndrome?
Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, researchers are following 200 infants with congenital
Zika syndrome and their families to understand the ongoing health impact, why some babies affected by the virus develop more normally than others, and if more positive prognoses are linked with family or environmental characteristics.
Congenital
Zika syndrome refers to the pattern of birth defects among fetuses and infants of mothers infected with Zika virus during pregnancy.
Since 2016, when Zika was declared by the World Health Organization as a public health emergency of international concern, the virus has become established in more than 80 countries, infected millions of people, and left many babies with birth defects (collectively called congenital
Zika syndrome).
Although one of the most serious consequences of the Zika virus (ZIKV) in infants is microcephaly, there is a broad collection of anomalies now known as congenital
Zika syndrome (CZS).
Not exact matches
Most people who get
Zika have mild symptoms — and many don't even realize they have the virus — but the disease can cause severe neurological problems, including Guillain - Barre
Syndrome in adults and microcephaly in fetuses.
The World Health Organization has said there is strong scientific consensus that
Zika can also cause Guillain - Barre, a rare neurological
syndrome that causes temporary paralysis in adults.
The WHO says there is strong scientific consensus that
Zika is a cause of the birth defect microcephaly, or small heads in babies, as well as Guillain - Barre
syndrome, a neurological disorder.
«Infants with congenital
Zika virus
syndrome suffer serious visual impairment: 100 % of Brazilian infants with confirmed and suspected
Zika were born with vision problems.»
The fetal disease caused by
Zika virus could soon have a new name:
Zika virus congenital
syndrome.
When Thomas Monath, an expert on vaccines combating mosquito - borne diseases, thinks about developing an inoculation against
Zika virus, he has a major concern: Guillain — Barré
syndrome.
The team who found a range of fetal conditions beyond microcephaly, all linked to the virus, suggest calling it
Zika virus congenital
syndrome
The mosquito - borne
Zika virus has been around for decades, but recently grew into an international health emergency following its association with severe birth defects and with Guillain - Barré
syndrome, and its rapid spread in Central and South America.
Patricia Garcez examines the cellular and molecular effects of
Zika virus congenital
syndrome during brain development.
In the last 10 years, outbreaks of potentially pandemic influenza, Middle East Respiratory
Syndrome Coronavirus, Ebola, and
Zika have threatened populations around the world.
It is known that
Zika can cause microcephaly, a severe birth defect in babies born to women infected with the virus, and Guillain - Barré
syndrome, a neurological condition that can lead to muscle weakness and, in severe cases, paralysis.
And because
Zika is so often missed — thanks to lab complications or patients» choice not to seek care — it is challenging to prepare for the possibility of Guillain — Barré
syndrome, too.
The recent rapid spread of
Zika virus and its unexpected linkage to birth defects and an autoimmune neurological
syndrome have generated worldwide concern.
The authors also looked at a temporal association between
Zika infection and an increase in cases of Guillain - Barré
syndrome.
They note that the rubella epidemic of the 1960s, when tens of thousands of babies were born with congenital rubella
syndrome in the United States, can provide important lessons learned that may be directly applicable to
Zika research.
Zika virus infection during pregnancy has been linked to congenital brain abnormalities, including microcephaly, and
Zika virus is a trigger of Guillain - Barré
syndrome.
To build their tool, Alison Galvani, from Yale University in New Haven, USA, and colleagues focused on the two known serious consequences of
Zika infection: microcephaly, a condition in which children are born with a small brain causing mental impairment, and Guillain - Barré
syndrome or GBS, a potentially fatal disease that can cause neural damage and paralysis.
Zika can also cause a serious neurologic disorder called Guillain - Barré
syndrome.
In a new paper published this week in the American Journal of Medical Genetics, first author Miguel del Campo, MD, PhD, associate professor in the Department of Pediatrics at University of California San Diego School of Medicine, and colleagues in Brazil and Spain, describe the phenotypic spectrum or set of observable characteristics of congenital
Zika (ZIKV)
syndrome, based upon clinical evaluations and neuroimaging of 83 Brazilian children with presumed or confirmed ZIKV congenital infections.
Brazil, El Salvador, and French Polynesia also suspect
Zika virus may have led to increased cases of a neurological disorder in adults called Guillain - Barre
syndrome that causes temporary paralysis.
Congenital
Zika virus
syndrome — a pattern of birth defects found among fetuses and babies infected with the virus — is a newly identified condition that occurs when women are infected during pregnancy.
It is unknown to what degree the amount of
Zika virus in the mother, the extent of
Zika symptoms or the presence of prior dengue antibodies contribute to the
syndrome.
With its rapid spread throughout Central and South America,
Zika has emerged as a severe health threat that can cause microcephaly in newborns, as well as Guillain - Barre
syndrome in children and adults.
Although
Zika causes no harm in most people it infects, its possible role in clusters of microcephaly in babies and Guillain - Barré
syndrome in adults led the World Health Organization on 1 February to declare that it is a «public health emergency of international concern.»
Growing evidence suggests that virus causing
Zika can trigger a rare side effect called Guillain - Barré
syndrome
Dr. Siqueira said she and her colleagues are now investigating whether the problem was the result of an auto - immune disorder sparked by one of the viruses that caused the immune system to attack nerve cells, similar to what occurs in
Zika patients who develop Guillain - Barré
Syndrome.
In addition to microcephaly, other birth defects and probably Guillain - Barré
syndrome (a neurological disorder),
Zika may be
Zika was known for 60 years as a mild virus that appeared sporadically, but since 2007, two troubling shifts have taken place, Dye said:
Zika virus now results in widespread outbreaks of hundreds or thousands of cases, and it is associated with neurological disorders like microcephaly and Guillain - Barre
syndrome, a disorder in which the body's immune system attacks the nerves.
«Although we are still working to establish causality with
Zika, we can not tolerate the prospect of more babies being born with neurological and other malformations, and more people facing the threat of paralysis due to Guillain — Barré
syndrome.
«Many unanswered questions remain about the links between
Zika virus disease, microcephaly and Guillain — Barré
syndrome,» noted Etienne.
The variation in the E glycoprotein of
Zika virus could explain the ability of the virus to attack nerve cells, as well as the associations of
Zika virus infection with birth defects and the autoimmune - neurological Guillian - Barré
syndrome.
Zika infection is also strongly associated with Guillain - Barré
Syndrome (GBS), an autoimmune disease that attacks the peripheral nervous system, leading to rapidly progressive and potentially life - threatening muscle weakness.
«In addition to microcephaly, infection with
Zika virus in adults can lead to destruction of myelin, a mixture of proteins and fatty substances that insulate nerves to speed electrical communication between neurons, a condition called Guillain - Barre
syndrome.»
There is a causal link between
Zika infection and at least two serious diseases: microcephaly and Guillain - Barré
Syndrome (GBS).