Sentences with phrase «zika vaccine research»
PHILADELPHIA --(April 19, 2018)-- The Wistar Institute and partners at the Perelman School of Medicine at the University of Pennsylvania, Inovio Pharmaceuticals, and GeneOne Life Science were recognized among the Top 10 Clinical Research Achievement Awards by the Clinical Research Forum for their ground - breaking phase 1 DNA - based Zika vaccine research — the first trial of a Zika vaccine in humans, which proved safe and effective.
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National and local health care officials said cuts in federal spending to combat the Zika virus means fewer pregnant women will be tested and there will be less money available to develop a vaccine and research how the disease affects fetal brains.
The scourge of Zika prompted a similarly international research effort, which has already resulted in potential vaccine candidates.
Healthy adults mounted strong immune responses after receiving an investigational whole inactivated Zika virus vaccine, according to interim analyses of three Phase 1, placebo - controlled, double - blind trials conducted at Beth Israel Deaconess Medical Center (BIDMC), Walter Reed Army Institute of Research (WRAIR), and Saint Louis University School of Medicine.
The first live - attenuated Zika vaccine still in the development stage completely protected mice against the virus after a single vaccination dose, according to new research from The University of Texas Medical Branch at Galveston and Instituto Evandro Chagas at the Ministry of Health in Brazil.
«This research team's dedication and previous research on dengue and other arboviruses enabled them to quickly develop this model for Zika virus, an important first step to enable testing of candidate vaccine and therapeutics,» said Stephen Higgs, PhD, the president of the American Society of Tropical Medicine and Hygiene.
«Given the key similarities to human infections, a marmoset model of Zika may be useful for testing of new drug and vaccines,» said Texas Biomedical Research Institute virologist Jean Patterson, Ph.D. «Having an animal model of Zika infection to study may help us identify places where we might be able to block transmission.»
Science's picks for Areas to watch in 2017 are human embryo research, Zika vaccine trials, the search for Planet Nine, and the impacts on research of the U.S. election and «Brexit» vote.
The Walter Reed Army Institute of Research (WRAIR) and collaborators at the Beth Israel Deaconess Medical Center and Harvard Medical School have completed a promising preclinical study of two Zika vaccine candidates that suggests that an effective human vaccine will be achievable.
«Zika vaccines protect mice from infection: NIH - funded research suggests human vaccine is possible.»
In a previously published paper, Barouch and colleagues, including Colonel Nelson L. Michael, MD, PhD, director of the Military HIV Research Program at the Walter Reed Army Institute of Research (WRAIR) and Stephen Thomas, MD, Upstate Medical University, State University of New York, demonstrated that three different vaccine candidates provided robust protection against Zika virus in both mice and rhesus monkeys.
(Case in point: On June 28, political disputes once again derailed vaccine research support when the U.S. Senate blocked a $ 1.1 billion Zika bill.)
«The pace of preclinical and early clinical development for Zika vaccines is unprecedented,» said Barouch, corresponding author and director of the Center for Virology and Vaccine Research at BIDMC.
Speaking to reporters covering the Capitol Hill rollout of the report, Flake wondered aloud: «Explain why, when we need research done — when we need a vaccine for Ebola or Zika — why are we spending money on cheerleaders?»
He said that prior research has shown that it is very hard to completely debunk misinformation, such as the mistaken belief that the MMR vaccine causes autism, but the study results suggest that accurately communicating about the risks of Zika can help lessen the detrimental effects of the misbelief.
Nelson Michael of the Walter Reed Army Institute of Research in Silver Spring, Maryland, says that the trial Zika vaccine will be tested on mice and monkeys that already have antibodies to dengue, to see if that interferes with the vaccine.
But since a substantial part of the harmful effects of Zika virus infection may occur in the early part of pregnancy, administering vaccines prior to pregnancy or early in pregnancy may be most beneficial, and more clinical research is needed for this time period.
«Zika epidemic highlights need for priority vaccine research for pregnant women.»
A research team that includes scientists with Kansas State University's Biosecurity Research Institute has developed a promising Zika virus research team that includes scientists with Kansas State University's Biosecurity Research Institute has developed a promising Zika virus Research Institute has developed a promising Zika virus vaccine.
«This vaccine is a successful advancement in developing control strategies for Zika virus by creating widespread immunity in susceptible populations,» said Stephen Higgs, director of the Biosecurity Research Institute.
This paper showcased research results from the new DNA - based Zika vaccine that is based on synthetic DNA and gives instructions to the body's immune system to produce antibodies to attack Zika antigens (i.e. bacteria, viruses, and other foreign substances that trigger immune responses from the body.)
The clinical research center CAIMED, part of Ponce Health Sciences University in Puerto Rico, will examine the vaccine's safety and immunogenicity in participants who have already been naturally exposed to Zika or dengue viruses
The Walter Reed Army Institute of Research (WRAIR) began vaccinations today in a Phase 1 human clinical trial to test the safety and immunogenicity of the Zika purified inactivated virus (ZPIV) vaccine.
In 2016, Moderna received a funding award of up to $ 125 million from the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS), to accelerate development of its Zika mRNA vaccine.
De Silva and Metz were recently named to a global research consortium to tackle Zika, and they're using the same nanoparticle vaccine platform as they work to develop a Zika vaccine.
Scientists could be one step closer to developing long - awaited vaccines against viruses such as Zika, West Nile or HIV, thanks to research at Penn State College of Medicine.
UNC School of Medicine's Aravinda de Silva, PhD, who is currently working on NIH - funded Zika vaccine development and other Zika research, is a co-author.
The working group's recent recommendation to include pregnant women in the Zika virus vaccine research agenda has already reached a global audience.
A vial of the NIAID Zika Virus Investigational DNA Vaccine, taken at the NIAID Vaccine Research Center's Pilot Plant in Frederick, Maryland.
The Walter Reed Army Institute of Research (WRAIR) announces a Cooperative Research and Development Agreement for the development of a Zika vaccine candidate with Sanofi Pasteur, the vaccines division of Sanofi.
A research article published in the journal Science has reported the efficacy of three different vaccine platforms against the Zika virus in rhesus macaque monkeys.
More than a dozen experimental clinical therapies and vaccines have been developed from research from the Weiner laboratory, including the first Zika vaccine in clinical trials, as well as a novel immunotherapy for HPV - associated cancer and precancer.
«We want to identify some important pathways in Zika pathogenesis, which we hope will inspire the experts in treatment and vaccine research,» he added.
A research team at the Washington University School of Medicine in St. Louis is using genetically modified mice to be able to test possible vaccines and treatments against the Zika virus.
In other news, research on a potential vaccine for the Zika virus entered early clinical trials last week.
This research was in mice, so it can't directly translate to humans, but it does suggest that a vaccine against Zika could spur protective antibodies that not only prevent people from getting the virus, but could protect a pregnant woman's fetus.