Sentences with word «abacavir»

A recent example of co-pending cases involves Viiv Healthcare's abacavir combination drugs — where Apotex's case started 4 months after Teva's case [5].

The Federal Joint Committee (G - BA) specified two appropriate comparator therapies according to the approval status: Treatment - naive patients, i.e. patients who had not been treated for HIV before, were to receive efavirenz in combination with tenofovir and emtricitabine or in combination with abacavir and lamivudine.

Clinical trials have now shown that screening patients for HLA - B * 5701 before treatment has dramatically reduced the number of side effects being experienced from abacavir use.

Each day, half the volunteers received one pill containing efavirenz and another containing abacavir and lamivudine.

The other volunteers got tenofovir instead of the efavirenz, as well as the abacavir - lamivudine pill.

In 2002, two groups identified a particular gene variant in the major histocompatibility complex (MHC), called HLA - B * 5701, as being the key factor in hypersensitivity to abacavir.

Individuals with the HLA - B * 5701 allele were found to be more likely to have a hypersensitivity reaction to abacavir.

In 2002, two groups identified a particular gene variant, called HLA - B * 5701, as being the key factor in hypersensitivity to abacavir.

One example is abacavir, a drug used in conjunction with other antiretrovirals in the treatment of HIV infection.

In individuals found to have the HLA - B * 5701 allele, abacavir is avoided, and alternative HIV treatments are given.