The induced pluripotent stem cells (iPSCs) that the new method produces have the same
ability as embryonic stem cells to turn into any kind of tissue.
Not exact matches
The
ability of SIF - seq to use reporter assays in mouse
embryonic stem cells to identify human
embryonic stem cell enhancers that are not present in the mouse genome opens the door to intriguing research possibilities
as Dickel explains.
Induced pluripotent
stem cells (known
as iPSCs) are similar to human
embryonic stem cells in that both
cell types have the unique
ability to self - renew and have the flexibility to become any
cell in the human body.
The
ability of a fertilized egg to generate both
embryonic and extra-
embryonic tissues is referred to
as «totipotency,» an ultimate
stem cell state seen only during the earliest stages of
embryonic development.
The research used skin samples from five men to create what are known
as induced pluripotent
stem cells, which closely resemble
embryonic stem cells in their
ability to become nearly any tissue in the body.
Stem cells (be they
embryonic cells or adult
cells that have been induced back to an
embryonic - like state) have an amazing
ability to become any other living
cell as long
as the right genetic and external signals are applied.
Yamanaka and Takahashi began their search by studying
embryonic stem cells in the hope of identifying the genes that underlie essential
stem cell characteristics, such
as pluripotency and proliferation, a
cell's
ability to replicate itself.
Editing
embryonic stem cells was concluded to be a non-viable route,
as these
cells lose the
ability to become germ
cells when in culture.
While it has long been known that
embryonic stem cells have the
ability to develop into any kind of tissue - specific
cells, the exact mechanism
as to how this occurs has heretofore not been demonstrated.
As he devised his scheme, he relied heavily on knowledge from the field of
embryonic stem (ES)
cells, which naturally possess the
ability to specialize into any type of adult
cell.
* The role of the US in global efforts to address pollutants that are broadly dispersed across national borders, such
as greenhouse gasses, persistent organic pollutants, ozone, etc...; * How they view a president's
ability to influence national science policy in a way that will persist beyond their term (s),
as would be necessary for example to address global climate change or enhancement of science education nationwide; * Their perspective on the relative roles that scientific knowledge, ethics, economics, and faith should play in resolving debates over
embryonic stem cell research, evolution education, human population growth, etc... * What specific steps they would take to prevent the introduction of political or economic bias in the dissemination and use of scientific knowledge; * (and many more...)