Dr. Group continues: «Ingestion of fulvic acid is known to increase
the ability of a cell to release toxic metals.
Problem is that certain amino acids and fats cause fat to enter the cell and disrupt
the ability of the cell to make insulin receptors.
This approach involves first generating many monoclonal antibodies raised against «crude» tumor cell antigen populations — whole cells and cell membranes — and then screening for those that block the metastatic
ability of the cell.
Downregulation of tumor suppressors and upregulation of proto - oncogenes can directly inhibit
the ability of a cell to undergo programmed cell death while simultaneously stimulating growth and division.
An obvious requirement for metastasis is motility,
the ability of a cell to get up and go.
To test whether their synthetic membranes had the signaling
ability of cell membranes, the researchers added a touch of sodium chloride salt.
However, based on
the ability of cell extracts that are defective in two different TFIIH components (XPD and XPB) to complement NER activity in vitro [26], it is likely that TFIIH (or its components) can either multimerise or exchange at least during the NER reaction.
Cellular plasticity is
the ability of a cell to make different cell types.
When bortezomib blocks
the ability of the cell to clear these protein clumps, they grow larger and become toxic to the cancer cells.
The team demonstrated that cell sex considerably influenced cellular uptake of nanoparticles and found that cells from men and women responded differently to reprogramming techniques used to enhance
the ability of the cells to differentiate into a greater variety of cell types.
Its impact appears to reduce
the ability of the cells in the eye's trabecular meshwork to continually move the clear aqueous humor out of the front of the eye and dump it into the body's general circulation, said Liu, corresponding author of the study in the journal Investigative Ophthalmology & Visual Science.
«We've been able to show that the engineered cells produce the HIF - 1 inhibitor, and this molecule goes on to inhibit HIF - 1 function in cells, limiting
the ability of these cells to survive and grow in a nutrient - limited environment as expected.
The new tool emerged from the PhD project of Yara Sánchez - Corrales from the Grieneisen Lab on cell polarity:
the ability of cells to distribute internal proteins in order to facilitate communication, movement or growth.
But hair growth depends on
the ability of cells in the hair follicles to keep dividing and so producing cells which die and are built into the hair shaft.
In all species where it has been shown to delay aging and the diseases of aging, it affects the regulation of energy and
the ability of cells and the organism to respond to changes in the environment as they age.»
According to cardiologist Stefanie Dimmler at the University of Frankfurt in Germany, degraded telomeres might cause heart disease by impeding
the ability of cells from the bone marrow to repair damaged parts of the arterial walls.
Andrey Lavrov and Igor Kosevich, MSU biologists, researched
the ability of the cells of marine sponges (Porifera) to reaggregation — a process, during which the artificially separated sponge cells reaggregate and build multicellular aggregates of varying types.
«The problem,» says Dr. Snyder, «is that current methods for selecting anti-viral immune cells may inadvertently limit
the ability of those cells to restore life - long immunity.»
Many biological processes depend on
the ability of cells to stick to one another.
We also examined the invasive
ability of these cells using Matrigel invasion chamber and found that miR - 7 was also able to block the invasion of CSCs through Matrigel (Fig. 4A, right).
We then examined the metastatic
ability of these cells by implanting various doses of CSCs into mice via intracardiac injection.
Using lab - grown mouse astrocytes with variant forms of NHE9, the researchers found a change in the pH (acidity) inside cellular compartments called endosomes, which in turn altered
the ability of cells to take up glutamate.
Given
the ability of cells in the body to participate in repair, it is imperative to understand how to harness such a property at will.
More recently, the process of EMT was associated with
the ability of cells to initiate experimental tumors — a key - trait ascribed to «cancer stem cells».
«For instance, if you've got hepatitis B infection, then you're going to have impaired macrophage function in the liver, which is going to impair
the ability of those cells to go on and respond to other viruses.
The ability of cells to remain unaffected by HIV, in the absence of CCR5, has already been shown clinically, but this strategy has not been joined with gene therapy in making killer cells.
An alternative mechanism that might explain
the ability of cells to transit between multiple states is oscillating gene expression.
Nutritional deficiencies impair lung growth, favour infections and decrease
the ability of cells to control inflammatory processes, for example through a lack of anti-oxidative factors.
We have focused on
the ability of all cells to act as antigen presenting cells and utilizing TLR agonists that affect both leukemic cell immunogenicity and anti-leukemia immune response.
This spectrum in gene expression is reflected in
the ability of cells to undergo self - renewal or to form specific differentiated cell types.
SAN FRANCISCO, CA — Scientists at the Gladstone Institutes have discovered a key protein that regulates insulin resistance — the diminished
ability of cells to respond to the action of insulin and which sets the stage for the development of the most common form of diabetes.
Our cells are exposed to DNA damaging agents daily, such as UV irradiation, and as we age
the ability of our cells to repair these... >> MORE
Many aspects of human health can be traced to
the ability of cells to sense and respond to infection, injury or other environmental changes.
Honey actually provides direct fuel in the form of glucose to the wound, increasing the speed and healing
ability of these cells.
The chemicals in cigarette smoke have been shown to interfere with
the ability of cells in the ovary to make estrogen.
ThyroMend ™ is used by healthcare professionals to increase naturally production of thyroid hormones by the thyroid gland, increase conversion of T4 to the more active T3 hormone, and increase
the ability of cells to respond to thyroid hormones.
The ability of cells to perceive and correctly respond to the signals is critical for growth and development, tissue repair, and immunity as well as normal homeostasis in every tissue.
In addition, the vegetable boosted
the ability of the cells to resist further harm perpetrated by free radicals.
It contains the potent neurotoxin grayanotoxin which can disrupt
the ability of the cells of the body to return to their normal state after excitation.
Not exact matches
Adult brains actually do grow new brain
cells through the incredible process
of neurogenesis, improving your memory, stabilizing your mood, and boosting your
ability to handle stress.
«Important issues can be things like the employee's
ability to use
cell phones at work or while driving; dealing with the appropriate way (or inappropriate way) that employees discuss the employer in chat rooms or on blogs after hours; or even the
ability of the employer to address issues created by the ways the employees use their computers, e-mail, and voice mail,» Cooper says.
Increased
ability to burn fat: Research shows that cold - induced glucose uptake results in the creation
of brown fat
cells, which create warmth, burn energy and keep you slim.
Reviewers have dubbed the second - generation iPod Touch the iPhone's baby brother, with many
of the same features — music and video player, Safari Web browser, email, iTunes store, etc. — minus the
ability to make
cell phone calls.
That's attached to the progress
of sequencing technology, the
ability to edit
cells, and other gene editing approaches have been transformative in the immunotherapy world in recent years.
One
of the defining features that HMD Global is pitching is the phone's
ability to play the video game Snake, a puzzle game that was widely available on yesteryear's
cell phones.
These risks and uncertainties include: Gilead's
ability to achieve its anticipated full year 2018 financial results; Gilead's
ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's
ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's
ability to develop and commercialize
cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's
ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's
ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's
ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's
ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's
ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
I don't know about you, but I think it's more humane to terminate a cluster
of cells that lacks the
ability to feel pain than it is to insist that a child be born into a situation where it is unwanted, unloved, unprotected and may end up abused or dead.
Indeed, the
ability to clone animals, such as Dolly the sheep, by fusion
of an adult
cell to an enucleated oocyte demonstrates that the epigenetic programming responsible for maintaining an adult
cell in a stable state can be erased by factors present in the cytoplasm
of the oocyte.
The formation
of the white blood
cells, essential in fighting infection, is reduced in severe PEM, and the
ability of white blood
cells to engulf and consume bacteria is decreased.
There is but one theory, known to me, that casts any positive light on the
ability of brain
cells to furnish us with feelings.