Sentences with phrase «ability of each endothelial cell»
The ability of the endothelial cells to form capillary - like structures was assessed by placing them on the solubilized basement membrane preparation Matrigel (Becton Dickinson, San Jose, CA), according to the manufacturer's instructions.
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In earlier studies involving animal models and human cancer cell lines, researchers found that breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a cancer cell's ability to spread.
Key elements of the immune system, they also have the ability to turn into several cell types after having passed the endothelial barrier, in order to fulfil different functions depending on the tissue.
As shown in Fig. 4B, suppressive ability of miR - 7 on both transmigration through endothelial cells and Matrigel was significantly attenuated by ectopic expression of KLF4, suggesting that miR - 7 suppresses invasive ability of CSCs by blocking KLF4 expression.
Each of the endothelial cell lines demonstrated an ability to orient into capillary - like structures when placed onto a Matrigel surface (Fig. 5A) ⇓.
The ability to up - regulate endothelial cell adhesion molecules after exposure to cytokines was unaffected by repeated subculturing of cells, because we noted identical staining patterns for passage 30 cells (we did attempt to extend this observation to include later passage cells).
Endothelial cells that had undergone two sessions of FACS - based selection were evaluated for their ability to metabolize fluorescence - labeled acetylated LDL (DiI - Ac - LDL).
The impaired ability of human corneal endothelial cells (HCECs) to divide, both in vivo and in culture, has been well documented in the scientific literature for a number of years [1 - 6].
A key feature of endothelial cells switched to their angiogenic phenotype is their ability to invade the surrounding space.
Tube - forming ability of purified CD31 + endothelial cells derived from induced pluripotent stem cells after VEGF treatment.