Sentences with phrase «ability of embryonic stem cells»

New research at the Hebrew University of Jerusalem sheds light on pluripotency — the ability of embryonic stem cells to renew themselves...

By designing synthetic proteins that can only interact with a pre-determined partner, and introducing them into cells, the team revealed a key interaction that regulates the ability of embryonic stem cells to change into other cell types.

Not exact matches

The ability of SIF - seq to use reporter assays in mouse embryonic stem cells to identify human embryonic stem cell enhancers that are not present in the mouse genome opens the door to intriguing research possibilities as Dickel explains.

The latest findings show that genetic defects in the body's ability to manufacture carnitine might be associated with an increased risk of autism because carnitine deficiency interferes with the normal processes by which neural stem cells promote and organize embryonic and fetal brain development.

The induced pluripotent stem cells (iPSCs) that the new method produces have the same ability as embryonic stem cells to turn into any kind of tissue.

Further investigation, says Resar, showed that these unusual properties arise from the ability of HMGA1 to turn on several genes involved in the Wnt pathway, a network of proteins necessary for embryonic development and stem cell activity.

«Embryonic stem cells are pluripotent, meaning they have the ability to become any type of tissue,» Fuchs says.

This study provides experimental evidence which shows the important role of RNA levels in the controlling the fate of embryonic stem cells, and shows an understanding of RNA's ability to differentiate stem cells at the molecular level.

- Our results provide new insights into the mechanisms of how POLR3G gene regulates stem cell state, which in turn sheds light on the complex mechanisms with which human embryonic stem cells both self - renew and maintain the ability to differentiate.

The researchers discovered that this region is required to both turn Sox2 on, and for the embryonic stem cells to maintain their characteristic appearance and ability to differentiate into all the cell types of the adult organism.

Mitchell and her colleagues eliminated this possibility when they deleted these nearby regions in the genome of mice and found there was no impact on the gene's ability to be turned on in embryonic stem cells.

The ability of a fertilized egg to generate both embryonic and extra-embryonic tissues is referred to as «totipotency,» an ultimate stem cell state seen only during the earliest stages of embryonic development.

Studying mouse embryonic stem cells, they removed Grb2, a protein essential to the ability of the stem cell to transform into other cell types, from the cells.

Both teams successfully used these to reprogramme skin cells in a lab dish into cells resembling embryonic stem cells, which have the ability to turn into any tissue of the human body.

While the potential of adult stem cells has been understood for some time, researchers have argued that the pluripotency of embryonic stem cells — their ability to be transformed into most if not all of the various cell types of the body — make them more valuable both for research and potentially someday for treatment.

Yamanaka and Takahashi began their search by studying embryonic stem cells in the hope of identifying the genes that underlie essential stem cell characteristics, such as pluripotency and proliferation, a cell's ability to replicate itself.

While it is widely accepted that embryonic stem cells (ESCs) have the ability to become any type of cell, the molecular causes for this characteristic are still under much investigation, although one suspected player is chromatin.

The new cells, which Yamanaka called induced pluripotent stem (iPS) cells, looked and behaved like embryonic stem cells, which are prized for their ability to transform themselves into almost any kind of tissue and, perhaps, someday cure disease — a more distinct possibility now that President Barack Obama has loosened restrictions on stem cell research.

A whole network of these proteins is involved in giving embryonic stem (ES) cells pluripotency — the ability to generate all the cell lineages of the body.

Embryonic stem cells, discovered in the Department of Genetics in the 1980s (for which Sir Martin Evans was awarded the Nobel Prize in Physiology or Medicine 2007), have become an important tool for developmental biology, understanding disease, and in regenerative medicine due to the ability to give rise to all cell types in culture.

But the eyebrow - raising reports claimed that adult stem cells sometimes behave like their embryonic counterparts, mimicking their trademark capacity to engender all types of cells — an ability dubbed pluripotency.

While it has long been known that embryonic stem cells have the ability to develop into any kind of tissue - specific cells, the exact mechanism as to how this occurs has heretofore not been demonstrated.

An important concept in this research is pluripotency ---- the ability of the human embryonic stem cell to differentiate or become almost any cell in the body, explained senior author Kenneth S. Kosik, professor in the Department of Molecular, Cellular & Developmental Biology (MCDB).

Currently, stem cell research focuses on renewal and differentiation of stem cells and the molecular mechanisms of its pluripotency - or their ability to develop into any type of cell - using human embryonic stem cells, induced pluripotent stem cells, and stem cells in simpler organisms.

As he devised his scheme, he relied heavily on knowledge from the field of embryonic stem (ES) cells, which naturally possess the ability to specialize into any type of adult cell.

* The role of the US in global efforts to address pollutants that are broadly dispersed across national borders, such as greenhouse gasses, persistent organic pollutants, ozone, etc...; * How they view a president's ability to influence national science policy in a way that will persist beyond their term (s), as would be necessary for example to address global climate change or enhancement of science education nationwide; * Their perspective on the relative roles that scientific knowledge, ethics, economics, and faith should play in resolving debates over embryonic stem cell research, evolution education, human population growth, etc... * What specific steps they would take to prevent the introduction of political or economic bias in the dissemination and use of scientific knowledge; * (and many more...)