Sentences with phrase «ability of osteoblasts»
High levels of cortisol also decrease the ability of osteoblasts to synthesize new bone and interfere with absorption of Ca2 + from the gastrointestinal tract.
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The study revealed that MSCs isolated from the bone marrow of patients with elevated bone marrow metal concentrations had lost the ability to differentiate into bone - forming osteoblasts.
In vitro assays of the osteoblast cultures derived from the MT1 - / - and MT2 - / - mice showed a cell intrinsic defect in the proliferation, differentiation and mineralization abilities of MT2 - / - osteoblasts compared to WT counterparts and the mutant cells did not respond to melatonin addition.