Brodsky was part of a team that developed the modified Ham test that measures levels of components of serum,, a protein - rich liquid in blood, and showed it was effective in diagnosing atypical hemolytic - uremic syndrome (aHUS), a genetic disorder in which
abnormal blood clots form in small blood vessels in the kidneys.
Vitamin K - most cats with hepatic lipidosis have
abnormal blood clotting ability due to inability of the liver to recycle vitamin K dependent blood clotting factors.
This tendency is a problem
when abnormal blood clots form, break off, and lodge in places where they blocks off (occludes) normal blood flow.
Patients with nephrotic syndrome have high blood pressure and may develop
abnormal blood clots resulting in a variety of signs associated with occluded or blocked blood vessels, or edema (swelling), especially of the legs or abdomen.
These pathologies fall broadly into four categories: coagulopathy,
where abnormal blood clotting is caused; haemorrhaging, where bleeding occurs; neurotoxicity, which damages the nervous system causing paralysis, and cytotoxicity, where the bite causes death of cells and destruction of tissue.
Elevated fibrinogen may decrease blood flow, especially through partially blocked arteries may promote the formation
of abnormal blood clots inside coronary arteries and directly contribute to the atherosclerosis process by binding to LDL.
The diseases that result
from abnormal blood clotting, vessel occlusion with clots, and inflammation from clot dissolution are called thromboembolic or thrombotic diseases.
Serial blood work evaluation is recommended to detect the systemic side effects of heat stroke including abnormal heart rhythms, liver damage, kidney failure, neurologic derangements, and
abnormal blood clotting ability.
Heatstroke can cause permanent organ damage and
abnormal blood clotting.
The formation of large,
abnormal blood clots, known as arterial thromboembolism, is a common problem in cats with cardiomyopathy.
Cats with HCM also are prone to
abnormal blood clots, which can form and block major blood vessels.
DVT occurs when
an abnormal blood clot forms in a large vein — typically in the lower leg, thigh, or pelvis, but they can also occur in the arms.