Sentences with phrase «abnormal blood vessel»

These are big words for a very small abnormal blood vessel but, in fact, the PDA is the most common congenital heart defect of the dog.

In cats, a condition that results in abnormal blood vessel development to the liver and within the liver can seriously interfere with the organ function.

This is an abnormal blood vessel that allows the blood to bypass the liver, preventing blood to get cleansed by one of the body's filters (the liver).

That was the research niche that we set out to explore to see if we could find a new way of targeting the abnormal blood vessel growth that occurs in wet AMD.

Choroidal neovascularization (CNV), the underlying process causing wet AMD and abnormal blood vessel growth, is the body's misguided way of attempting to create a new network of blood vessels to supply more nutrients and oxygen to the eye's retina.

For wet AMD, treatments aimed at stopping abnormal blood vessel growth include FDA - approved drugs called Lucentis, Eylea, Macugen and Visudyne used with Photodynamic Therapy or PDT.

In the less common wet AMD, something (scientists aren't sure what) spurs abnormal blood vessel growth, and central vision can be lost in a matter of weeks or days.

Further research also will help determine which if any of these drugs is safer for glaucoma patients who also have abnormal blood vessel growth.

Ultimately, Wars2 provides researchers and pharmaceutical companies a fresh new target for developing treatments for diseases characterized by abnormal blood vessel growth that may be more effective and specific or complementary to what is currently available.

«Finding a way to control angiogenesis not only provides a target for the development of anti-cancer therapies, but may also prove useful in similarly starving abnormal blood vessel growth elsewhere in the body, like in diabetic eye disease.»

Working with mice, a multicenter team of researchers has found a new way to reduce the abnormal blood vessel growth and leakage in the eye that accompany some eye diseases.

Roughly 20 percent of patients with age - related macular degeneration suffer from abnormal blood vessel growth and vascular leakage, says Campochiaro, and so may be helped by this new therapy, if it proves to work in clinical trials.

Biology may also play a role — for example, a greater propensity towards abnormal blood vessel function during emotional stress, such as exaggerated constriction of coronary or peripheral blood vessels.

Currently, wet AMD patients are treated with frequent (as often as once a month) injections into the eye of a drug that blocks one of the major stimulators of abnormal blood vessel growth.

The gene MAP2K1 has previously been linked to some types of cancerous growths as well as to conditions that lead to abnormal blood vessel formation in the head, face or neck.

Earlier research by other scientists has shown that the drug verteporfin, used to treat abnormal blood vessel formation in the eye, acts on the YAP pathway inhibiting the protein's YAP function.

If your baby was born prematurely — especially if he was very premature, had an infection, or needed treatment with oxygen — he's at greater risk for developing certain eye problems, including astigmatism (blurred vision), myopia (nearsightedness), retinopathy of prematurity (abnormal blood vessel growth that can lead to blindness), and strabismus (eye misalignment).

An advanced stage, called proliferative diabetic retinopathy, occurs when abnormal blood vessels grow near the retina, the light - sensitive tissue at the back of the eye.

The device can treat either form of age - related macular degeneration: the dry stage, where the delicate tissues of the macula become thinned and slowly lose function, or the less common wet stage that's caused by the growth of abnormal blood vessels behind the macula.

In this study, we found that chloroquine not only has an effect on the growth of the cancer cells, but also makes the tumor environment less aggressive by normalizing the abnormal blood vessels in the tumor,» says Patrizia Agostinis.

However, a recent study by investigators at VIB and KU Leuven has demonstrated that chloroquine also normalizes the abnormal blood vessels in tumors.

ROP is a condition that causes abnormal blood vessels to grow in the retina (back of the eye) and can cause retinal detachment, which is a major cause of childhood blindness globally.

It's thought that the high pressure observed in tumors is a result of these abnormal blood vessels, which leak fluid and proteins into the area between tumor cells, known as the interstitial space.

Since the majority of severe visual loss is caused by abnormal blood vessels growing beneath the retina, a massive effort is underway to identify methods of arresting this process.

A problem in this research arena — called antiangiogenesis — has been finding a compound that is selective, closing off abnormal blood vessels only in the diseased organ while leaving all others intact.

Pulmonary hypertension develops because of abnormal blood vessels in the lungs, which makes it harder for the heart to push blood through and provide oxygen to the rest of the body.

Summary: Use of eye injections of drugs aimed at slowing the growth of abnormal blood vessels in the eye is becoming more common for the treatment of individuals with many eye problems including macular degeneration, diabetic retinopathy and retinal artery or vein blockage.

We know with the wet form that one of the major features is the abnormal blood vessels, and we know that if we stop that we can potentially halt the disease.

We were very excited to find that our compound, at fairly low doses, could quite significantly block the formation of abnormal blood vessels in this model.

«Instead of treating patients after these abnormal blood vessels form in the eye, we may be able to give patients eye drops or systemic medications that prevent their development in the first place.»

One class of drugs, called vascular endothelial growth factor inhibitors, for example, is designed to thwart the growth of abnormal blood vessels in the eye.

Great for your immune system and liver, reishi mushrooms have been described as having «lifespan - extending properties» because they're helpful in preventing abnormal blood vessels from forming.

A special diagnostic procedure allows the surgeon to check the exact location of the abnormal blood vessels prior to surgery.

The treatment is almost always a surgical procedure in which the abnormal blood vessels are removed.

Conversly, the «wet» form of macular degeneration is characterized by the growth of abnormal blood vessels from the choroid underneath the macula which then go on to create «blind spots» in a patient's field of vision.

Not exact matches

When there is an increase in blood circulation at the time of pregnancy, the blood vessels may branch outwards and appear abnormal.

Preeclampsia (previously called toxemia) typically occurs during the second or third trimester of pregnancy and may be related to an abnormal interaction of blood vessels that supply the placenta.

Two protein molecules that fit together as lock and key seem to promote the abnormal formation of blood vessels in joints affected by rheumatoid arthritis, according to researchers at the University of Illinois at Chicago College of Medicine, who found that the substances are present at higher levels in the joints of patients affected by the disease.

ROP involves an abnormal growth of blood vessels in the retina that may lead to scarring, retinal detachment and, in severe cases, blindness.

In humans, abnormal and excessive blood vessel growth related to decreased oxygen supply is the most common cause of blindness in premature babies, diabetics, and the elderly.

Although such abnormal tau clusters are found in brain diseases including Alzheimer's, their location in CTE is unique — near small blood vessels, and most often near the bottom of sulci, the deep folds in the brain's cortex.

Placentas had underdeveloped blood vessels, the barrier between mother and fetal cells was abnormal, and researchers spotted evidence of cellular stress.

The concept of tailoring drugs to regulate and treat abnormal brain blood vessels is a novel treatment strategy and offers great potential to complement existing treatments of this debilitating disease.»

In the U.S., one in every four deaths is a result of heart disease, which includes a range of conditions from arrhythmias, or abnormal heart rhythms, to defects, as well as blood vessel diseases, more commonly known as cardiovascular diseases.

In sickle cell anemia, a single genetic mutation leads to abnormal, crescent - shaped red blood cells that clot in tiny blood vessels throughout the body, causing severe pain and eventual organ damage.

Many diseases are characterised by abnormal or poor blood vessel formation.

For example, chronic wounds are the result of insufficient blood vessel formation, while age - related macular degeneration is the result of abnormal expansion of blood vessels which interfere with normal processes.

The researchers used computed tomography (CT) scans to evaluate the severity of abnormal calcium deposition in one of the largest blood vessels in human body, the abdominal aorta.

Linda Shavit, MD (University College London Medical School, in the UK, and Shaare Zedek Medical Center, in Israel) and her colleagues wondered whether the heart problems experienced by kidney stone formers might be due to abnormal deposits of calcium in their blood vessels.

AMD is described in stages — early, intermediate, and late — with vision loss occurring in late - stage AMD, either from atrophy or abnormal new blood vessels.