Summary: Use of eye injections of drugs aimed at slowing the growth of
abnormal blood vessels in the eye is becoming more common for the treatment of individuals with many eye problems including macular degeneration, diabetic retinopathy and retinal artery or vein blockage.
One class of drugs, called vascular endothelial growth factor inhibitors, for example, is designed to thwart the growth of
abnormal blood vessels in the eye.
Not exact matches
Earlier research by other scientists has shown that the drug verteporfin, used to treat
abnormal blood vessel formation
in the
eye, acts on the YAP pathway inhibiting the protein's YAP function.
ROP is a condition that causes
abnormal blood vessels to grow
in the retina (back of the
eye) and can cause retinal detachment, which is a major cause of childhood blindness globally.
Working with mice, a multicenter team of researchers has found a new way to reduce the
abnormal blood vessel growth and leakage
in the
eye that accompany some
eye diseases.
In AMD, the retinal pigment epithelial (RPE) cells that support the cells in the eye that detect light wear out, and there is also the growth of abnormal, leaky blood vessels below the retin
In AMD, the retinal pigment epithelial (RPE) cells that support the cells
in the eye that detect light wear out, and there is also the growth of abnormal, leaky blood vessels below the retin
in the
eye that detect light wear out, and there is also the growth of
abnormal, leaky
blood vessels below the retina.
«Finding a way to control angiogenesis not only provides a target for the development of anti-cancer therapies, but may also prove useful
in similarly starving
abnormal blood vessel growth elsewhere
in the body, like
in diabetic
eye disease.»
Because, of course, it is this
abnormal proliferation of
blood vessel cells, which we term angiogenesis,
in the back of the
eye that is the key feature of wet AMD.
«Instead of treating patients after these
abnormal blood vessels form
in the
eye, we may be able to give patients
eye drops or systemic medications that prevent their development
in the first place.»