Furthermore, they found that certain chemicals could slow
abnormal bone growth in the stem cells, a discovery that might help guide future drug development.
Once the team derived the stem cells, they identified a cellular mechanism that
drives abnormal bone growth in the thus - far untreatable bone disease, called fibrodysplasiaossificans progressiva (FOP).
In serious cases, it can show up in the form
of abnormal bone growth, poor eye and / or brain development, and overworked livers and / or kidneys.
Liver contains very high levels of vitamin A, and when fed routinely to a cat for several months, can cause
abnormal bone growth due to excessive vitamin A accumulation in the tissues.
Radiographs showed changes consistent with craniomandubular osteopathy, a congenital disorder common in the Westie breed, that is an excessive and
abnormal bone growth on the skull (cranium) and lower jaw (mandible) causing pain and discomfort.
Chronic overexposure to fluoride can result in weakened bones or
abnormal bone growths as well as chronic gastric disorders.
CiRA scientists use iPS cells to show that a molecule associated with inflammation could be a therapeutic target for
the abnormal bone growth.
«This is especially important, because once
an abnormal bone growth occurs, it is permanent.»
«Stem cells used to model disease that causes
abnormal bone growth.»
Otosclerosis,
an abnormal bone growth in the middle ear, ran in her family, and an infection precipitated her deafness.
There is also evidence that ingesting high levels of fluoride can cause
abnormal bone growth.
Abnormal Bone Growth and Development
This condition affects the weight - bearing joints (hips, knees, elbows, shoulders), causing loss of lubricating fluids, wearing away of cartilage, and
abnormal bone growth.
«If a large breed dog gets too much calcium, it can cause
abnormal bone growth and lead to expensive and painful problems in the future,» says Shmalberg.
Large breeds fed excess calcium are more likely to suffer from developmental bone disease such as osteochondrosis (
abnormal bone growth).
Too much liver will cause vitamin toxicity and
abnormal bone growth (these can be lethal).