«The findings provide new insight into how
cells faithfully transmit this organizational information as embryos develop, and into what goes wrong when cellular
development goes awry, thereby giving rise to
abnormal cell development and diseases such as
cancer,» says senior study investigator Danny Reinberg, PhD, professor of biochemistry and molecular pharmacology at NYU Langone and a Howard Hughes Medical Institute investigator.
When mutated, or not working properly,
cells with
abnormal tumor suppressor genes are more likely to grow out of control and lead to the
development of
cancer.