Sentences with phrase «abnormal cell proliferation»

To achieve this goal, the center's clinical and basic investigators are engaging in four distinct yet synergistic projects: 1) identifying mechanisms of abnormal cell proliferation, 2) examining the role of thrombosis in the development of PAH, 3) studying the role of nitric oxide deficiency in PAH, and 4) testing two existing drugs to restore lost cellular function due to a genetic mutation related to PAH.

Not exact matches

«One of the major and immediate downstream effects of myc activation is a dramatic increase in the capacity of affected cells to make protein,» Ruggero said «This, in turn, leads to increased cell survival and proliferation, and to unstable genomes that foster additional mutations that turn these abnormal cells into tumor cells.»

Lymphomas are caused by an abnormal proliferation of white blood cells and can occur at any age.

At present, Barrett's esophagus and esophageal cancer are diagnosed using biopsies, which look for signs of dysplasia, the proliferation of abnormal cancer cells.

In Wilms tumors, one set of mutations promotes abnormal and continued proliferation of the undifferentiated cells.

The elevated incidence of glomerulonephritis in p21 - deficient mice, with increased severity among females, has been reported previously (35) and is attributable to an autoimmune process produced by abnormal proliferation of memory T - cell lymphocytes.

Some of those hits affect tyrosine kinases, enzymes that promote cancer by stimulating abnormal cell growth and proliferation.

These abnormal cells — in the case of pulmonary hypertension, those that line the blood vessels leading to the lungs — release signals that stimulate the growth of small new blood vessels to feed the renegade cells, allowing further proliferation, and thickening of the vessel walls.

Because, of course, it is this abnormal proliferation of blood vessel cells, which we term angiogenesis, in the back of the eye that is the key feature of wet AMD.

Sunflower seeds are also a good source of selenium, which has been shown to induce DNA repair and synthesis in damaged cells, to inhibit the proliferation of cancer cells, and to induce their apoptosis, the self - destruction mechanism the body naturally produces to eliminate worn out or abnormal cells.

Selenium has been shown to induce DNA repair and synthesis in damaged cells, to inhibit the proliferation of cancer cells, and to induce their apoptosis, the self - destruct sequence the body uses to eliminate worn out or abnormal cells.

If you know someone who is fighting the dreaded proliferation of abnormal cells (that's what cancer is) you should do careful research, starting with the knowledge that the average cost to treat a cancer patient was $ 670,000 in 2011 and survival rates had not improved.

Cancer begins through mutations at the cellular level, which leads to an abnormal proliferation of abnormal cells.

It is a whole complex of diseases typified by uncontrolled proliferation of abnormal cells.