Sentences with phrase «abnormal circuits in the brain»

Not exact matches

Psychiatric disorders are in fact brain disorders that involve abnormal activity in brain circuits, so having researchers who understand the brain in a deep and integrated way is going to be critical for the future, says Thomas Insel, director of the US National Institute of Mental Health (NIMH).

«We wanted to find the link between the abnormal structure of synapses in the FXS mouse, and the behavioral abnormalities at the level of brain circuits; that had not been previously established,» said senior author Dr. Carlos Portera - Cailliau, an associate professor in the departments of neurology and neurobiology.

A new study by Columbia University Medical Center (CUMC) researchers strongly supports the latter, demonstrating that abnormal tau protein, a key feature of the neurofibrillary tangles seen in the brains of those with Alzheimer's, propagates along linked brain circuits, «jumping» from neuron to neuron.

Uhlhaas and colleagues summarize decades of work to hypothesize that «in ASDs abnormal brain maturation during early prenatal and postnatal periods results in cortical circuits that are unable to support the expression of high - frequency oscillations during infancy.