Sentences with phrase «abnormal development in»

They may also be the result of abnormal development in puppies from merle to merle breedings.
The U.S. National Institutes of Health's National Toxicology Program — a government program that coordinates federal studies of chemicals» adverse effects — warns that BPA exposure may lead to abnormal development in infants and the Canadian government last year banned its use in baby bottles.
Miscarriages usually occur when there is a chromosomal abnormal development in an egg or embryo, in which the body responds by eliminating the pregnancy.
According to the Mayo Clinic, the cause of SIDS is unknown, although it may involve an abnormal development in the baby's brain that takes care of his ability to breathe and wake up from sleep.

Not exact matches

Moreover, in human physiology, androgyny and gynandry refer to abnormal human sexual development in which an admixture of male / female sexual organs is present in one human.
She found that milestone achievement was abnormal in these monkeys: at six to eight weeks they were slow in starting to manipulate, and at ten months the increase in «motor disturbance behaviors» that normally occurs was prolonged.101 The author concludes, «These effects could occur as a result of effects on vulnerable brain processes during a sensitive period, interference with programming of [normal] brain development by endogenous [internal] agents or alteration in early experiences.»
Furthermore, if the blanket is wrapped too tightly around the hips, it can lead to hip dysplasia, a condition that causes the ball of the hip to become dislocated from the hip socket, resulting in abnormal development of the hip joint.
Any device that restrains a baby's legs in an unhealthy position should be considered a potential risk for abnormal hip development.
In contrast, speech and language disorder refers to abnormal language development.
In fact, any device that restrains baby's hips and legs in an unnatural position can risk abnormal hip developmenIn fact, any device that restrains baby's hips and legs in an unnatural position can risk abnormal hip developmenin an unnatural position can risk abnormal hip development.
Excessive alcohol, when transferred to a breastfed baby, can depress the central nervous system and cause drowsiness and deep sleep, abnormal weight gain, and, in extreme cases, retarded mental or motor development.
Illingworth RS (1987) Abilities and reflexes of the newborn in «The development of the infant and young child: Normal and abnormal», 9th edition, ELBS: 60 - 82.
Researchers pin down two genes that may be responsible for abnormal neural development in Down's mice embryos.
«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.
In animal studies, stationary chick and mouse fetuses have abnormal bones and joints, suggesting that movement is crucial to proper development.
Researchers from UC Davis School of Medicine and Shriners Hospitals for Children — Northern California have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome.
Mice exposed to 30 or more minutes of ultrasound in utero had abnormal brain development, for instance.
«Determining the role of ZNF804A is the first step in understanding how schizophrenia - associated genes contribute to abnormal brain development,» said Mao.
Investigators at Duke University, led by Erica Davis, PhD, a co-senior author of the report, blocked the gene's expression in zebrafish, which resulted in abnormal facial cartilage, smaller eyes and structural abnormalities of neurons involved in the development of reproductive organs.
The observation of an abnormal state of matter in a two - dimensional magnetic material is the latest development in the race to harness novel electronic properties for more robust and efficient next - generation devices.
Driven by revelations of lead in children's toys, hormone - mimicking chemicals in plastic baby bottles and controversial flame - retardants in furniture, state environmental officials drafted a set of rules aimed at products with chemicals that have been linked to illness or abnormal development
Approximately 42 % of children in the study with MRI findings of MS developed the first clinical symptoms of the disease about two years after the abnormal MRI, which shows a faster development of the disease than has been reported in adults.
The researchers found that a common cleft lip and palate gene mutation resulted in abnormal development of salivary gland ducts such that they could not properly pump the buffering liquid and protective immune compounds into the mouth.
Lahn and his colleagues looked at the abnormal spindle - like microcephaly associated (ASPM) gene, which scientists had previously identified as a key player in brain development.
Damage to the BSCB, explained the researchers, plays a fundamental role in the development of several pathological conditions, including abnormal motor function.
«The abnormal inflammation seen in women with PCOS may be a factor in the development of these conditions.»
The report indicates that Sestrin 3 plays a critical role in regulating molecular pathways that control the production of glucose and insulin sensitivity in the liver, making it a logical target for drug development for type 2 diabetes and metabolic syndrome, which can produce increased blood pressure, abnormal cholesterol levels and insulin resistance.
In a paper published recently in the Journal of Clinical Investigation, lead authors at the University of Georgia, along with colleagues from the Rensselaer and the University of California at San Diego, demonstrated for the first time that the gene NDST1 plays a significant role in the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDIn a paper published recently in the Journal of Clinical Investigation, lead authors at the University of Georgia, along with colleagues from the Rensselaer and the University of California at San Diego, demonstrated for the first time that the gene NDST1 plays a significant role in the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDin the Journal of Clinical Investigation, lead authors at the University of Georgia, along with colleagues from the Rensselaer and the University of California at San Diego, demonstrated for the first time that the gene NDST1 plays a significant role in the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDin the proper development of the diaphragm, and that abnormal expression of the gene could lead to CDH.
Neurocutaneous disorders are caused by abnormal development of cells in the embryonic stage, leading to tumors in various parts of the body, including the skin, organs, bones, brain and spinal cord.
The musashi protein also has interesting implications for the development of drugs trying to prevent abnormal memory loss that occurs in diseases such as Alzheimer's.
They found that two specific genes, DLX1 and DLX2, regulate GABA synthesis during brain development, and that mutations to the genes resulted in abnormal brain maturation.
«Some neuropsychiatric disorders, such as schizophrenia and autism, are characterized by the abnormal development of synaptic connectivity in certain key parts of the brain,» explains Schneggenburger.
Indeed, fewer progenitors and, consequently, neurons were produced, likely explaining the abnormal brain development in the absence of thyroid hormones.
Research findings indicate that abnormal CaSR function and / or abundance play a significant role in the development or progression of several non-communicable diseases (or NCDs) such as Alzheimer's disease, cardiovascular diseases, diabetes, cancer, and degenerative muscle loss.
The involvement of this enzyme in susceptibility to oxidative stress, which has frequently been observed in autistic children, its association with gastrointestinal diseases — which often accompany autistic disorders — and its role in nerve development and neurotransmission mean it is an ideal candidate for deregulation of its expression to lead to the abnormal brain development observed in ASD.
The resulting impairment in calcium management leads in turn to abnormal mitochondrial turnover and impaired mitochondrial energy production, which delays neuronal development.
Both groups that received andro showed significant increases in estradiol — a potent female hormone that causes abnormal breast development in men.
The technique also detected three cases of other chromosomal disorders that lead to abnormal development, Quake's group reports online today in the Proceedings of the National Academy of Sciences.
«Finding a way to control angiogenesis not only provides a target for the development of anti-cancer therapies, but may also prove useful in similarly starving abnormal blood vessel growth elsewhere in the body, like in diabetic eye disease.»
In the study, published in the journal eLife, co-senior authors Assistant Professor Shawn Je from Duke - NUS and Assistant Professor Zeng Li from NNI have shown how one brain - specific microRNA (miR - 128) plays a key role in causing abnormal brain developmenIn the study, published in the journal eLife, co-senior authors Assistant Professor Shawn Je from Duke - NUS and Assistant Professor Zeng Li from NNI have shown how one brain - specific microRNA (miR - 128) plays a key role in causing abnormal brain developmenin the journal eLife, co-senior authors Assistant Professor Shawn Je from Duke - NUS and Assistant Professor Zeng Li from NNI have shown how one brain - specific microRNA (miR - 128) plays a key role in causing abnormal brain developmenin causing abnormal brain development.
Thomas Look and colleagues use a type of genomic screen and identify abnormal HGF expression as a crucial factor for development of a class of acute leukemia in leukemia cell lines and clinical samples.
Lewy bodies (accumulation of abnormal alpha - synuclein A protein in the human brain that is associated with the development of Parkinson's.
She is a pioneer in tissue engineering / microfabrication and smooth muscle development and seeks to understand the biomechanical and dynamic molecular mechanisms that influence tissue remodeling during development, wound repair and abnormal cell growth.
Targeted disruption of IRF - 1 or IRF - 2 results in abnormal type I IFN gene induction and aberrant lymphocyte development.
Any of these situations can cause abnormal development and growth and can result in a genetic syndrome.
We report here that inner ears of Lcc / Lcc mice fail to establish a prosensory domain and neither hair cells nor supporting cells differentiate, resulting in a severe inner ear malformation, whereas the sensory epithelium of Ysb / Ysb mice shows abnormal development with disorganized and fewer hair cells.
Evidence that A beta immunization also reduces cognitive dysfunction in murine models of Alzheimer's disease would support the hypothesis that abnormal A beta processing is essential to the pathogenesis of Alzheimer's disease, and would encourage the development of other strategies directed at the «amyloid cascade».
Phthalates are endocrine system disruptors known to cause infertility, reduced testosterone levels and, most worrisome, cause abnormal development of the male reproductive system while in utero.
The main birth defect attributed to Zika is microcephaly, a rare neurological condition in which an infant is born with a much smaller head — an effect of abnormal brain development.
Mfrprd6 mice demonstrate abnormal RPE microvilli development, a delay in outer segment development, an impaired ability to phagocytize shed OSs, and potentially, an impairment of adhesion between RPE and outer segments.
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