Sentences with phrase «abnormal genes»

Abnormal genes, whether mutated or not, form the basis for inherited disease.

Indeed, many diseases have their basis in abnormal genes.

Breeding animals with abnormal genes to each otherproduces different phases of corn snakes.

Inherited disorders are conditions that arise due to abnormal genes that are passed down from one generation to another.

But, abnormal genes make up about 10 percent of breast cancer cases, so fundraisers like this with Reese Witherspoon are critical.

A genetic test examines a DNA sample of a person's cells for abnormal genes, or analyzes the number, arrangement and characteristics of the chromosomes.

According to Reeves, the result suggests that genes in the DSCR make their mischief by interacting with other abnormal genes far away on chromosome 21, and that the genetics of Down syndrome are probably more complex than has been generally thought.

Another important group of possible causes of age - related macular degeneration is mildly abnormal genes.

Gene therapy is designed to introduce genetic material into cells to compensate for or correct abnormal genes.

Within a single tumor exists such an astonishingly varied population of cells, each with its own combination of normal and abnormal genes, that at least some cells nearly always have a way to survive any particular attack.

In February, the FDA agreed to allow 23andMe and its competitors to resume marketing tests for autosomal - recessive diseases, which result when both parents carry an abnormal gene.

This experimental drug homes in on the abnormal gene suspected to cause Dishman's disease.

One has to receive a copy of the abnormal gene from both parents to have the disease,» said Dr. Buchanan, who holds the Children's Cancer Fund Distinguished Chair in Pediatric Oncology & Hematology.

The discovery of an abnormal gene in narcoleptic pooches may soon lead to relief for millions of people who suffer from chronic insomnia.

«ALK now becomes the second abnormal gene that we are able to successfully target in lung cancer with drugs other than chemotherapy.»

An abnormal gene created by the fusion of ETV6 and the RUNX1 gene is one of the most common alterations in childhood ALL and is found in the leukemic cells of 20 to 25 percent of pediatric ALL.

R6 / 2 mice have been genetically altered with an abnormal gene that makes them produce a harmful fragment of the mutant huntingtin protein

The finding wasn't surprising, Fallin explains — numerous studies have identified abnormal gene expression of immune genes in autism samples and environmental experiences such as prenatal infection or prenatal exposure to pollutants that can ramp up immune responses are risk factors for ASD.

For practical purposes, both mutations and epimutations ultimately harm us in the same way: by causing abnormal gene expression.

A University of Tokyo research group has discovered that genome - wide epigenetic disorder is behind patterns of abnormal gene expression found in adult T - cell leukemia - lymphoma...

Most people suffering from metabolic disorders have an abnormal gene which results in the deficiency or malformation of a hormone or enzyme.

If she has an abnormal gene — most commonly BRCA1 or BRCA2 — that risk shoots up to 80 percent.

Researchers have identified the gene mutation that causes NEwS, and a DNA test is now available that allows breeders to avoid producing affected puppies by never breeding two dogs to each other if they are both carriers of the abnormal gene.

This means that each parent must carry an abnormal gene and that two parents who are not affected themselves may produce affected puppies.

Both parents must carry the abnormal gene for the offspring to be affected.

With this type of disease, there are no unaffected «carrier» cats — all cats with an abnormal gene will be clinically affected.

The OptiGen test detects the mutant, abnormal gene copy and the normal gene copy.

The abnormal gene dominates the gene pair.

It is thought that disease results from the combination of an abnormal gene (causing an abnormal structure of the SAA protein), and also infectious or environmental factors that cause systemic inflammation and so increase the production of this protein in affected cats.

Recently the DNA mutations which cause vWD in several breeds have been identified and accurate tests for the presence of the abnormal gene exist for use in those breeds.

The University of Minnesota Canine Genetics Laboratory completed the genome association study and identified the abnormal gene sequence, then began working on a DNA test to allow for breeding dogs to be screened.

Affected cats (homozygous - having two copies the same - for the abnormal gene) arise when affected or carrier cats are mated with each other.

Not exact matches

«We can look at the genes that are abnormal in brain tumors [and] develop therapies to attack those genes.»

«We wondered whether some of those same genes could also cause seizures if they were expressed in the brain and, if so, whether those genes would also place people with epilepsy at risk not only for having epilepsy but also an abnormal heart beat and risk of death,» said Noebels.

In a common subtype of acute myeloid leukemia, this abnormal activation of such self - renewing genes is apparently caused by structural modifications of the DNA packaging.

Baylin and other scientists have shown that EZH2 and its effects can precede abnormal DNA methylation in gene start sites.

A host of other genes, which control many other cellular processes do not show such abnormal DNA methylation after smoke exposure.

Those made with iPS cells, by contrast, tend to accumulate mutations and suffer abnormal patterns of gene activation.

Researchers pin down two genes that may be responsible for abnormal neural development in Down's mice embryos.

When these pattern - forming genes are mutated, embryonic cells have an abnormal pattern to follow.

The scientists looked for mutations, or abnormal changes in the DNA, and filtered out normal variations in genes that commonly occur among humans.

Animal experiments revealed that mice carrying a mutated SCN8A gene had reduced heart rate compared with their healthy littermates, and that administration of caffeine produced an abnormal heart rhythm known as accelerated idioventricular rhythm.

Finn Miller, a toddler born with Beckwith - Wiedemann syndrome, due to abnormal «imprinting» of genes, plays at home with his mother and older brother.

People with the transthyretin amyloidosis have mutations in the DNA of the transthyretin gene, which causes abnormal buildup and deposits of a transport protein called transthyretin in nerve and heart cells.

Intriguingly, DNA in many of the placenta samples has the same imprinting abnormality seen in Silver - Russell, but a dampened down version of it — perhaps a smaller stretch of the gene is affected, or gene expression is less abnormal.

Using RNA sequencing, the researchers found multiple genes whose abnormal expression could lead to the high rate of death for cloned embryos, including failure to implant in the uterus and failure to develop a normal placenta.

HD is caused by a mutation in the human HTT gene that results in an abnormal expansion and misfolding of the corresponding huntingtin protein.

To determine the effect of mutations that reduce TET2 function in abnormal stem cells, the research team genetically engineered mice such that the scientists could switch the TET2 gene on or off.

These genetic discoveries reinforce earlier gene studies implicating abnormal inflammation and fat metabolism in the disease.

«Determining the role of ZNF804A is the first step in understanding how schizophrenia - associated genes contribute to abnormal brain development,» said Mao.