Sentences with phrase «abnormal hemoglobin»

But thalassemia is different: Instead of abnormal hemoglobin, the main problem is a decreased amount of normal globin.

Sickle cells contain abnormal hemoglobin called sickle hemoglobin or hemoglobin S.

In 1948 British biochemist and evolutionary biologist J. B. S. Haldane noticed that the distribution of populations with abnormal hemoglobin coincides with the distribution of malaria.

A single DNA mutation causes the body to make sticky, crescent - shaped red blood cells that contain abnormal hemoglobin and can block blood flow in limbs and organs.

Good genes can help In 1948 British biochemist and evolutionary biologist J. B. S. Haldane noticed that the distribution of populations with abnormal hemoglobin coincides with the distribution of malaria.

Essentially, the aim is to genetically alter patients» own blood stem cells so they don't produce abnormal hemoglobin.

Did genes for abnormal hemoglobin survive and spread, he wondered, because they protected against malaria infection?

Sometimes the body manufactures abnormal hemoglobin, containing yet another combination of chains.

Such abnormal hemoglobins often do not transport oxygen efficiently and may also be unstable.

Sickle cell disease is a group of inherited blood disorders caused by genetic mutations in the HBB gene, resulting in abnormal hemoglobin, the iron - containing protein that normally allows blood cells to carry oxygen.

People with hemoglobin H disease have only moderate anemia, but they produce an abnormal hemoglobin called hemoglobin H containing of four b chains.

Abnormal hemoglobin, the protein that enables red blood cells to carry oxygen, causes sickle cells to acquire their crescent shape and rigidity.

Due to the breakdown of this abnormal hemoglobin, the spleen enlarges and may have to be removed.

It arises when a person inherits two copies of an abnormal hemoglobin gene — one from each parent.

In essence, Buchanan explained, the therapy «converted» the patient to sickle - cell trait — that is, a person who carries only one copy of the abnormal hemoglobin gene.