Sentences with phrase «abnormal number of chromosomes»

For more than 100 years, researchers have been unable to explain why cancer cells contain abnormal numbers of chromosomes, a phenomenon known as aneuploidy.

Li points out that, unlike yeast cells, human and mammalian cells have a protein called p53 that kills cells with abnormal numbers of chromosomes.

UroSEEK uses urine samples to seek out mutations in 11 genes or the presence of abnormal numbers of chromosomes that would indicate the presence of DNA associated with bladder cancer or upper tract urothelial cancer (UTUC).

Moreover, many human tumors have highly abnormal numbers of chromosomes (that is, they are aneuploid), with initial chromosomal loss participating in the early steps of the transformation cascade in inherited cancers caused by heterozygous mutation in tumor suppressor genes and the more widespread aneuploidy characteristic of advance tumors thought to drive acquisition of malignant growth properties.??

A fetus with an abnormal number of chromosomes can either have too many or too few chromosomes.

Early cell division is to some extent independent of the number of chromosomes in the embryo, so an embryo with an abnormal number of chromosomes can look just like any other.

An embryo that carries an abnormal number of chromosomes is «aneuploid».

That's because D7 embryos — which develop more slowly — are thought more likely to contain an abnormal number of chromosomes (aneuploidy).

She has been able to show in preliminary experiments that if the timing of early cell divisions does not follow a specific pattern, those embryos are much more likely to contain an abnormal number of chromosomes.

«One of the main causes of female infertility is a defect in the eggs that causes them to have an abnormal number of chromosomes.

Many tumors are characterized by «aneuploidy,» meaning they display an abnormal number of chromosomes and chromosomal segments.

Abnormal number of chromosomes is often associated with cancer development.

Aneuploidy is a condition in which cells contain an abnormal number of chromosomes, and is known to be the cause of many types of cancer and genetic disorders, including Down Syndrome.

They also observed that 41 percent of the clones had abnormal numbers of chromosomes (aneuploidy), 56percent were near - diploid (40 to 44 chromosomes), and 4 percent were tetraploid (84 chromosomes), whereas the large majority (86 percent) of non-fused cells were diploid.

Similarly, about 12 % of eggs had abnormal numbers of chromosomes, an aberration called aneuploidy.

The abnormal number of chromosomes seen in this individual may give clues to the origins of cancer.

His focus shifted to the abnormal number of chromosomes that virtually every cancer tumor has — an observation first made by German scientist Theodor Boveri in the early 20th century.

Aneuploidy (an abnormal number of chromosomes) is the most common genetic alteration in human tumors and a major cause for birth defects (Figure 4).

Researchers at the Department of Physiology, Development and Neuroscience at Cambridge report a mouse model of aneuploidy, where some cells in the embryo contain an abnormal number of chromosomes.

If the test result is abnormal (the tissue has an abnormal number of chromosomes), its good news.