Sentences with phrase «abnormal numbers of chromosomes»

Moreover, many human tumors have highly abnormal numbers of chromosomes (that is, they are aneuploid), with initial chromosomal loss participating in the early steps of the transformation cascade in inherited cancers caused by heterozygous mutation in tumor suppressor genes and the more widespread aneuploidy characteristic of advance tumors thought to drive acquisition of malignant growth properties.??

For more than 100 years, researchers have been unable to explain why cancer cells contain abnormal numbers of chromosomes, a phenomenon known as aneuploidy.

UroSEEK uses urine samples to seek out mutations in 11 genes or the presence of abnormal numbers of chromosomes that would indicate the presence of DNA associated with bladder cancer or upper tract urothelial cancer (UTUC).

Li points out that, unlike yeast cells, human and mammalian cells have a protein called p53 that kills cells with abnormal numbers of chromosomes.

«They have abnormal numbers of chromosomes, and they would develop abnormally, and so you can't use them.

An embryo that carries an abnormal number of chromosomes is «aneuploid».

That's because D7 embryos — which develop more slowly — are thought more likely to contain an abnormal number of chromosomes (aneuploidy).

«One of the main causes of female infertility is a defect in the eggs that causes them to have an abnormal number of chromosomes.

Many tumors are characterized by «aneuploidy,» meaning they display an abnormal number of chromosomes and chromosomal segments.

Abnormal number of chromosomes is often associated with cancer development.

Aneuploidy is a condition in which cells contain an abnormal number of chromosomes, and is known to be the cause of many types of cancer and genetic disorders, including Down Syndrome.

Aneuploidy (an abnormal number of chromosomes) is the most common genetic alteration in human tumors and a major cause for birth defects (Figure 4).

His focus shifted to the abnormal number of chromosomes that virtually every cancer tumor has — an observation first made by German scientist Theodor Boveri in the early 20th century.

If the test result is abnormal (the tissue has an abnormal number of chromosomes), its good news.

Not exact matches

But it also might be chromosome number two, and so if you have an abnormal amount of chromosome number two, and then the sperm comes in and meets it you either have only one or you might have three.

The discovery might also apply to cancer, because cancer cells often have abnormal numbers and arrangements of chromosomes.

As with most cancers, triple - negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes.

In 1914, German biologist Theodor Boveri postulated that abnormal chromosome number, or aneuploidy, might be a root cause of cancer.

A genetic test examines a DNA sample of a person's cells for abnormal genes, or analyzes the number, arrangement and characteristics of the chromosomes.