Not exact matches
These
abnormal proteins are prone to
aggregating with one another inside cells.
The Max Planck scientists could also show that a toxic
protein related to the
abnormal,
aggregate - forming
protein «huntingtin» of patients with the neurodegenerative Huntington's disease is efficiently destroyed by the newly identified pathway.
Intriguingly, brain cells (neurons) with decreased complex I levels are significantly less likely to contain Lewy bodies, the
abnormal protein -
aggregates that characterize Parkinson's disease,» says researcher Charalampos Tzoulis at Department of Clinical Science, UiB.
Several human neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's disease but also aging, are linked to an accumulation of
abnormal and
aggregated proteins in cells.