Sentences with phrase «abnormal protein in»

Dogs with multiple myeloma may have high blood calcium and abnormal protein in the urine.

Also Paul, I was diagnosed with MGUS (an abnormal protein in the blood)(Immunoglobulin M spike level) a year ago, however, was pleased to see that my MGUS score come down this last month.

LM22A - 4 treatment reduced the accumulation of abnormal proteins in the striatum and cortex — brain regions affected in Huntington's disease.

The problem with making blood stem cells proliferate outside the body is that the artificial growth gives rise to an accumulation of abnormal proteins in a part of the cell called the endoplasmic reticulum, ER.

There were also heightened levels of two abnormal proteins in the subjects» brains.

Turmeric binds to and dissolves abnormal proteins in the brain, helping to protect them from damage.

In thyroid cancer in dogs caused by parafocllicular cells can cause diarrhea resulting from the production of abnormal proteins in the C - cells.

Not exact matches

The cancerous cells win out over the healthy blood cells in the bone marrow, which in turn leads to kidney problems when the cancer cells make abnormal proteins instead of antibodies.

Food allergens are typically naturally - occurring proteins in foods or derivatives of them that cause abnormal immune responses.

This autoimmune disease is caused by an abnormal response to gluten, a protein found in grains such as wheat, rye, and barley.

Whey protein may cause abnormal heart rhythms, changes in cholesterol levels, headache, increased diabetes risk, increased fracture or osteoporosis risk, kidney dysfunction, liver damage, stomach or intestine symptoms (acid reflux, bloating, constipation, cramps, gas, increased bowel movements, movement problems, nausea, reduced appetite, swelling of limbs, and upset stomach), and thirst.

In an interview, the Glasgow - based neurologist described how he had examined sections of brain tissue in a retired rugby player and found abnormal proteins associated with head injuries and dementiIn an interview, the Glasgow - based neurologist described how he had examined sections of brain tissue in a retired rugby player and found abnormal proteins associated with head injuries and dementiin a retired rugby player and found abnormal proteins associated with head injuries and dementia.

Mad cow is the common name for bovine spongiform encephalopathy (BSE), a fatal disease caused by abnormal proteins (prions) in the brain and nervous system.

A study of 32,000 appendixes removed between 2000 and 2012 from British people born between 1941 and 1985 suggests that 1 in every 2000 people in the UK is carrying the abnormal protein, or prion, that causes the disease.

All these diseases share a common feature: abnormal buildup of a protein called tau in the brains of patients.

Greene and first author and doctoral student Gregory P. Way used machine learning to classify abnormal protein activity in tumors.

Payne keyed in the symptoms, and the computer program suggested a handful of potential conditions, including a rare disease called amyloidosis, in which abnormal proteins build up in the body, interfering with normal organ function and causing nerve damage.

Two protein molecules that fit together as lock and key seem to promote the abnormal formation of blood vessels in joints affected by rheumatoid arthritis, according to researchers at the University of Illinois at Chicago College of Medicine, who found that the substances are present at higher levels in the joints of patients affected by the disease.

People with the transthyretin amyloidosis have mutations in the DNA of the transthyretin gene, which causes abnormal buildup and deposits of a transport protein called transthyretin in nerve and heart cells.

The disease is caused by a genetic mutation that leads to abnormal clumps of protein in the brain, eventually resulting in the atrophy and death of nerve cells.

They found LM22A - 4 reduces abnormal protein accumulation, delays nerve cell degeneration, and improves motor skills in the animals.

HD is caused by a mutation in the human HTT gene that results in an abnormal expansion and misfolding of the corresponding huntingtin protein.

In mice engineered to lack the protein, the abnormal connections remained, suggesting BMP4 is key to the trimming (PLoS Biology, DOI: 10.1371 / journal.pbio.1001013).

Liu notes that this abnormal protein secretion occurs in other parts of the body as well with exfoliation syndrome, but appears to be problematic only in the eye.

Coeliac disease is caused by an abnormal reaction to gliadin, a gluten protein found in wheat (and similar proteins of the tribe Triticeae which includes other cultivars such as barley and rye).

These diseases originate when, for reasons not fully understood, normally harmless prion protein molecules become abnormal and gather in clusters.

The Chilean Rose Tarantula is the source of an important protein used in drugs to stop atrial fibrillation, an abnormal heart rhythm, or cardiac arrhythmia, which can result in death.

According to the proposal, called the amyloid hypothesis, Alzheimer's disease, estimated to affect more than 5 million people in the United States alone, is caused by abnormal buildup of A-beta protein in the brain.

Earlier research by other scientists has shown that the drug verteporfin, used to treat abnormal blood vessel formation in the eye, acts on the YAP pathway inhibiting the protein's YAP function.

Most people associate prion diseases with the brain, although scientists have found abnormal infectious prion protein in other organs, including the spleen, kidney, lungs and liver.

In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of toxic abnormal immunoglobulin called monoclonal protein that can damage multiple organs.

In abnormal [PSI +] cells, which are genetically identical to normal cells, the important protein clumps together, and the cells are unable to grow under certain conditions.

Multiple myeloma is preceded by a blood disorder called monoclonal gammopathy of undetermined significance (MGUS) in which abnormal plasma cells produce many copies of an antibody protein.

They also expressed abnormal levels of proteins involved in neurodegenerative conditions.

Other approaches target the abnormal accumulation of the protein tau in neurofibrillary tangles.

Prion diseases originate when normally harmless prion protein molecules become abnormal and gather in clusters and filaments in the human body and brain.

National Institutes of Health (NIH) scientists and collaborators at Case Western Reserve University School of Medicine have detected abnormal prion protein in the skin of nearly two dozen people who died from Creutzfeldt - Jakob disease (CJD).

Arising from the abnormal buildup of a protein known as alpha - synuclein in the brain, such conditions damage the nerves that control blood pressure and heart rate.

When present in tumors, both abnormal myc and abnormal mTOR are known to be able to rev up protein production and to foster cell growth.

«One of the major and immediate downstream effects of myc activation is a dramatic increase in the capacity of affected cells to make protein,» Ruggero said «This, in turn, leads to increased cell survival and proliferation, and to unstable genomes that foster additional mutations that turn these abnormal cells into tumor cells.»

Several of the proteins characteristic of cancer cells seem to show up in these nerve cells, and this is very abnormal.

In earlier studies, Ruggero found that myc not only drives protein production, but also that myc - driven cancer cells become absolutely dependent upon this ability to make abnormal amounts of protein.

Several factors have been implicated in Alzheimer's, including the build - up of an abnormal protein called beta amyloid, fibrous tangles in the brain involving abnormal forms of a protein called tau, and — most recently — an association between the disease and a gene called ApoE.

This turned out to be a normal protein in the cells of organisms throughout the animal kingdom — but in brains infected with scrapie and related diseases it turns up in both a normal, soluble form and an abnormal, insoluble form which accumulates in deposits that eventually kill the cells.

Published in the March 31 advance online issue of Cell, their findings reveal that circular RNAs — like their protein counterparts — are also affected by genomic rearrangements in cancer, resulting in abnormal fusions.

In Alzheimer's disease, an abnormal protein called amyloid beta begin s to appear on the neurons, forming plaques and compromising brain activity.

Detecting protein - protein interactions is key to understanding both normal and abnormal functions in the cell.

Amyloid — an abnormal protein whose accumulation in the brain is a hallmark of Alzheimer's disease — starts accumulating inside neurons of people as young as 20, a much younger age than scientists ever imagined, reports a surprising new Northwestern Medicine study.

Amyloid — an abnormal protein whose accumulation in the brain is a hallmark of Alzheimer's disease — starts accumulating inside neurons of people as young as 20, a much younger age than scientists ever imagined.

The mice had symptoms such as abnormal brain function, impaired memory and high levels of either amyloid - beta or tau proteins in the brain.