Sentences with phrase «abnormal proteins involved»

Other genetic defects associated with hypertrophic cardiomyopathy — six different genes have been linked to the disease — may work similarly by producing abnormal proteins involved in contraction, says Sweeney.

Not exact matches

They also expressed abnormal levels of proteins involved in neurodegenerative conditions.

Several factors have been implicated in Alzheimer's, including the build - up of an abnormal protein called beta amyloid, fibrous tangles in the brain involving abnormal forms of a protein called tau, and — most recently — an association between the disease and a gene called ApoE.

Gambetti, who was not involved in the new study, is co-author on a second NEJM paper appearing online today that shows that an assay similar to the CSF — based RT - QuIC test can pick up very small amounts of abnormal prion protein in the urine of people who have contracted a rare variant of CJD that is transmitted by consuming contaminated meat.

Using a multi-disciplinary approach involving electrophysiological, cellular and biophysical techniques, the researchers found that parts of the prion protein lacking the «brake» region produced abnormal electrical currents in cells.

Rather, the mutation produces an abnormal version of a protein involved in a process called phase separation in cells.

However, this cellular intervention alters the normal expression of hypophosphorylated retinoblastoma (RB) protein needed for the expression of genes involved in cell functions [3] and, therefore, results in an abnormal cell.

«The strong evidence that abnormal TDP - 43 protein is involved in the development of ALS, coupled with models that may replicate ALS more faithfully than other tools, may speed development of therapies for the thousands of individuals diagnosed with this devastating disease.»

Earlier lab work by the researchers helped explain key mechanisms involved with assisting vitamin D3 to clear the abnormal protein amyloid - beta, which is found within the plaque.

Scientists have identified a basic pathologic process underlying Alzheimer's development that involves the formation of abnormal protein deposits in the brain known as beta - amyloid plaques, but they still aren't entirely sure what causes this to happen.

Dr. Mara De Amici, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy 29th Congress of the European Academy of Allergy and Clinical Immunology, London, June 5 - 9, 2010 Abstract No. 1105 Background Specific foods and food additives can induce adverse gastrointestinal (GI) and cutaneous reactions, including food allergies that involve an abnormal immunologic reaction to food proteins or food intolerance which is not pathogenetically immune - mediated.

Alzheimer's Disease involves the accumulation of abnormal protein — either amyloid beta or Tau protein which gums up the brain system.

PLN involves loss of protein through the kidneys; PLE involves loss of protein through the intestines; and RD involves abnormal formation of the kidneys.

According to PetPlace.com, nephrotic syndrome in dogs is a disorder that involves a combination of factors: protein in the dog's urine, a low blood protein level, high cholesterol and abnormal fluid accumulation known as edema anywhere in the pet's body.

Abnormal proteins, called «amyloid» build up and inhibit brain cell function, particularly in brain regions involved with complex thought and memory.