«Our present study shows examination of the gene expression profiles at the very early age of initial clinical detection reveals both strong evidence of early biological processes in ASD and
abnormal signals with the potential to serve as an early, practical biomarker of risk for the disorder in general pediatric settings.»
Not exact matches
The researchers then treated animal models
with rapamycin, an approved anti-cancer drug, and found it halted the
abnormal signaling process and prevented the excessive division of HSCs lacking ItpkB.
«For the first time, we now have cellular evidence of
abnormal signaling in cells derived from women
with PMDD, and a plausible biological cause for their
abnormal behavioral sensitivity to estrogen and progesterone,» explained Schmidt.
Thyroid hormone interacts
with other hormones that control the menstrual cycle, and
abnormal levels of it can disrupt their
signals.