Sentences with phrase «abortive infection»

We have shown that most CD4 T cells die as a result of an innate immune response launched against cytoplasmic viral DNA accumulating as a result of abortive infection in these «bystander» CD4 T cells.

In a curious twist resembling cellular alchemy, when blood T cells are cultured with lymphoid tissue from the tonsils or spleen, the blood T cells begin acting like lymphoid tissue T cells, becoming more activated and more susceptible to abortive infection and death by pyroptosis.

Examples of such defense systems include receptor masking, restriction - modification (R - M) systems, DNA interference (Argonaute), bacteriophage exclusion (BREX or PGL), and abortive infection, all of which act in an innate, nonspecific manner.

As revealed in the Nature paper, this repetitive cycle of abortive infection, cell death, inflammation and recruitment of additional CD4 T cells to the infection «hot zone» ultimately destroys the immune system and causes AIDS.

Synthesis of human adenovirus early RNA species is similar in productive and abortive infections of monkey and human cells

Abortive infections In some instances, a cat can mount an effective immune response against the virus and completely eliminate it, but these abortive infections are rare.

Not exact matches

Now the Gladstone scientists report that these «bystander» cells are actually the victims of a failed or abortive form of viral infection.

Identified interferon - gamma — inducible protein 16 (IFI16) as a host DNA sensor required for CD4 T - cell death due to abortive HIV infection.