Researchers led by Baylor College of Medicine have developed a new computational method to study the function of disease - causing genes, starting with an important new discovery
about a gene associated with malaria — one of the biggest global health burdens.
His lab combines molecular biological, anatomical, physiological, imaging, and behavioral techniques to learn
about genes associated with neurodegenerative disease.
Not exact matches
A new mouse model of a genetically - linked type of autism reveals more
about the role of
genes in the disorder and the underlying brain changes
associated with autism's social and learning problems.
I remember looking at the report and realizing that there were all of these similar
genes in all of these different animals and thinking: «Maybe a careful reading of the papers
associated with the sequences most similar to mine will tell me something
about my own
gene.»
These differentially expressed microRNAs point the way toward finding more
genes associated with glaucoma, more clues
about how these glaucoma types each go
about damaging our optic nerve and potential new points of intervention, the scientists say.
Steve: And there's one of the researchers you quote in the article talks
about, there may be
genes that are not directly responsible for some aspect of brain function even at a biochemical cascade level; there might be a
gene that is responsible for the width of the birth canal and that that could be
associated with ultimately with intelligence.
However, in the wake of fatalities from
gene therapy and other technologies, as well as the potential for cancers
associated with stem cell transplants, governments are understandably nervous
about safety issues — not to mention the ethical maze of tinkering with fledgling life.
Variation in pigmentation among human populations may reflect local adaptation to regional light environments, because dark skin is more photoprotective, whereas pale skin aids the production of vitamin D. Although
genes associated with skin pigmentation have been identified in European populations, little is known
about the genetic basis of skin pigmentation in Africans.
«Although we know
about several
genes associated with ASD, a challenge and a major goal has been to find where in the nervous system the problems occur,» Ginty says.
Specifically, the new results boost knowledge
about the effects of the viral vector used, adeno -
associated virus, which has been successfully used in
gene therapy for the eye since 2008.
Harris cited other examples of concern — a review of 100 studies in the field of psychology in which the findings in only
about a third of the studies were reproducible; an effort by scientists at Bayer, another large drug company, that managed to reproduce the findings of only one - quarter of the studies under review; a just - published review of 25 historical candidate
genes for schizophrenia which found no evidence that the candidate
genes are more
associated with the disease than other
genes.
«We set out to find out
about human
genes that are implicated in the regulation of the gut microbiome, and we found some that are,» says senior author Ruth Ley, an
Associate Professor in the Department of Microbiology at Cornell University and the study's senior author.
Analyzing the DNA of
about 3,500 diagnosed people and nearly 11,000 without the disorder, researchers homed in on a genetic locus — a
gene's location on a chromosome — that's involved in the body's metabolic processes and seems to be
associated with the disorder.
These efforts produced a wealth of information
about how different
genes, and their
associated pathways, modulate aging in yeast.
Researchers suspect an autoimmune reaction is to blame because many people who develop narcolepsy — and just
about everyone with the vaccine -
associated form — have a specific variant in a
gene in the HLA family, which helps the body distinguish its own proteins from those made by microbial invaders.
As reported in the new study, the researchers were able to postpone the onset of hearing loss and
associated hair cell degeneration by
about a month, providing enough time to inject normal copies of the Clarin - 1
gene into the ear before the onset of hearing loss to see if the treatment was effective.
«The most exciting thing
about our study is not that we've identified a new
gene involved in pulmonary hypertension, but that we've found a drug that can «rescue» some mutations,» said co-senior author Wendy K. Chung, MD, PhD,
associate professor of pediatrics and medicine at CUMC.
Grace Kao,
associate ethics professor at Claremont School of Theology, in Claremont, California, mentioned additions she will make to her Introduction to Christian Ethics course, such as discussing epigenetic alterations
associated with war trauma for a session on war and peace, the science behind shopping and the ways that poverty can change your
genes for a segment
about economics, and an exploration of whether
genes can predict a person's liberalism and conservatism for a session on religion and politics.
It shares
about half its
genes with humans — including the mechanisms that are
associated with keeping the cells clean and tidy.
In terms of the potential impact of the risk -
associated variants,
about half the risk for both disorders appears to be accounted for by variants already known to influence the expression of
genes in the brain.
They noted that
about 80 percent of these
genes had not previously been
associated with antibiotic resistance.
We identified mutant phenotypes for 1,722
genes,
about two - thirds of which were not previously
associated with a phenotype.
Information
about whole genomes is now available for the first time,» said NHGRI 19s
Associate Director of Extramural Research Jane Peterson, Ph.D. «Previously, scientists were limited to gaining such information from one
gene at a time.
Dr Claire Haworth, Deputy Director on the influential Twins Early Development Study and King's College London and
Associate Professor in the Department of Psycology at the University of Warwick explains the main myths
about genes and genetics in education.
A special thanks to U.S. Rep.
Gene Green of Texas, who shared some thoughts
about energy production
associated with his Houston - area district, as well as an update on recovery efforts there after Hurricane Harvey, during an API Hill communicators event on Wednesday.
Wojcicki talked
about how 23andme's rich database of genotypic and phenotypic data (which users provide in response to surveys) is already helping
associate genes and variants of
genes with certain conditions.
Philadelphia, PA
About Blog Philly Family Life Counseling, LLC, the practice of Dr.
Gene Devers and
Associates, specializes in changing lives and relationships.
This approach and the threshold of 0.2 allows us to test our hypothesis that T cell DNA methylation is
associated with aggression trajectory and to generate further hypotheses
about the functions of
genes affected by the
associated methylation changes.
Right next to the
genes for independence and entrepreneurial spirit in sales
associates» DNA, there must be another
gene that makes them bristle at sitting in an office meeting and listening to a sales manager drone on
about office policy.