International consensus about genome editing of human embryos remains no more likely than
about embryo research in general: Some countries ban it while others actively promote and fund it.
The decade between the cloning of Dolly the sheep and the election of Barack Obama was rife with heated public arguments
about embryo research, cloning, assisted reproduction, and other matters bioethical.
Not exact matches
Rabbi Neuberger asserted that «it's really important that one accepts that... new scientific
research has taught us... that the human
embryo is not as unique as we thought before... We do have to think differently
about the «unique quality of human
embryos» in the way that Peter Saunders is saying... The miracle of creation... may have to be explained somewhat differently... Our human brains are given to us by God... to better the life of other human beings... and if this technology can do it..., and I don't believe that anybody is going to
research beyond fourteen days, then so be it, lets do it.»
The scientific community was not
about to give an inch to those who defended the rights of the
embryo, even if
embryo - destructive
research became unnecessary.
Such
embryo research might teach us more
about cell differentiation and early
embryo development, it might make possible greater success in bone marrow transplants, and it might help us to treat more successfully degenerative diseases and spinal cord injuries.
In a
research paper published in April last year, Chinese scientists described how they were able to manipulate the genomes of human
embryos for the first time, which raised ethical concerns
about the new frontier in science.
«Everything we talked
about was
about research directly on the embryo,» for example, to improve on infertility treatment or better understand cancer biology, says R. Alta Charo, a law professor and bioethicist at the University of Wisconsin Law School who was a member of the NIH Human Embryo Research Panel in the mid-1990s, which considered how embryos might be used in r
research directly on the
embryo,» for example, to improve on infertility treatment or better understand cancer biology, says R. Alta Charo, a law professor and bioethicist at the University of Wisconsin Law School who was a member of the NIH Human Embryo Research Panel in the mid-1990s, which considered how embryos might be used in res
embryo,» for example, to improve on infertility treatment or better understand cancer biology, says R. Alta Charo, a law professor and bioethicist at the University of Wisconsin Law School who was a member of the NIH Human
Embryo Research Panel in the mid-1990s, which considered how embryos might be used in res
Embryo Research Panel in the mid-1990s, which considered how embryos might be used in r
Research Panel in the mid-1990s, which considered how
embryos might be used in
researchresearch.
Another problem is that in its July 2009 Guidelines on Human Stem Cell
Research, NIH spelled out specific requirements about embryo donation for newly derived lines, says Pilar Ossorio, a legal scholar who studies research ethics at the University of Wisconsin Law
Research, NIH spelled out specific requirements
about embryo donation for newly derived lines, says Pilar Ossorio, a legal scholar who studies
research ethics at the University of Wisconsin Law
research ethics at the University of Wisconsin Law School.
Researchers in other countries have edited human
embryos to learn more
about early human development or to answer other basic
research questions (SN: 4/15/17, p. 16).
This is because of the obvious concerns
about the heritability of the genetic alterations induced, and the way in which such
research could spread from work on «non-viable»
embryos, to work on viable ones once this type of
research had been accepted in principle by international regulatory bodies.»
But since some members of Congress and millions of anti - abortion / pro-life radicals believe that
embryo research per se should be illegal, you'd better be pretty careful
about which eggs you break if you want to do
research on human
embryos.
A human
embryo — editing paper from a different Chinese team published in April 2015 touched off a worldwide debate
about the ethics of such experiments and led to calls for a
research moratorium.
Six years ago, President Bush limited federally funded
research to
about 20 viable lines of cells that had been extracted from
embryos prior to August 9, 2001.
A year of discussion
about the ethics of
embryo - editing
research, and perhaps simply the passage of time, seems to have blunted its controversial edge — although such work remains subject to the same ethical anxieties that surround other reproductive - biology experiments.
Fan's paper should help to reassure international observers
about the legitimacy of human -
embryo - editing
research in China, says Robin Lovell - Badge, a developmental biologist at the Crick.
The politics of
embryo research, however, is one reason we don't know more
about what distinguishes good eggs from bad.
The paper has split scientists, with consensus on the need for a moratorium on clinical applications but disagreement
about whether to support basic
research on editing genes in human sperm, eggs, or
embryos.
A second study, by a different
research group, tracked human and mouse
embryo development from fertilized egg to
about six days later, just before the
embryo implants in the uterine wall.
This relative absence of knowledge
about even the most prominent of the
embryo -
research issues is made emphatically clearer in the responses to particular questions of fact.
The debate
about genomic editing of human
embryos is unlikely to follow the recommendations for systematic forethought proposed by illustrious
research bodies and reports.
There were some who simply dismissed outright any ethical concerns
about destroying for
research so - called «leftover»
embryos from in vitro fertilization.
University of Wisconsin scientist, James A. Thomson, who first derived ESCs from
embryos, has said «if human embryonic stem cell
research does not make you at least a little bit uncomfortable, you have not thought
about it enough.»
In the past few days, you may have heard
about new
research describing the editing of the DNA sequence in human
embryos.
The
research will use donated
embryos left over from IVF treatments, and will follow them only through the point in their development when they have
about 250 cells.
«Stem cells in a healthy developing
embryo have a GPS system to alert them
about their position in the organ,» says Geoffrey Wahl, a professor in Salk's Gene Expression Laboratory, who led the
research.
Peter Braude, emeritus professor of obstetrics and gynecology at King's College London, said in a statement that the
research «is
about better understanding nature, not changing
embryos for implantation.»
Finally, let me say a word
about a matter that has been of deep concern to me — the expansion of federal funding for
embryo - destructive
research.
Previous
research from the team showed that using frozen
embryos resulted in more live births among women with polycystic ovarian syndrome — women who do not ovulate normally — but the researchers said not as much was known
about using fresh versus frozen
embryos in women who do ovulate normally.
Looking through a microscope, Youngnam Jin — a postdoctoral fellow in Randy Peterson's lab at Massachusetts General Hospital's Cardiovascular
Research Center — arranges one - celled zebrafish
embryos, each
about 10 minutes old, into rows of 20, spinning them with a micro spatula to turn their nuclei toward the ultrathin glass needle of a micro-injection device.
A copy of a news article
about controversial legislation to widen the scope of
embryo research and reactions to it in parliament and from the Catholic Church.
In explaining that «[m] any thoughtful and decent people are conflicted
about, or strongly oppose, this
research,» President Obama was acknowledging that, even in its earliest stages, the small group of cells that constitute an
embryo are in some way different from a chemical reagent to be sold in a catalog or an industrially synthesized molecule to be integrated into a widget.