Sentences with phrase «about gene expression»

But as we discuss here so often, life is about gene expression and the signals your send those genes.

But the image, by Fernan Federici and Lionel Dupuy of the University of Cambridge, is not just a pretty picture — it contains information about gene expression in the stem of genetically modified thale cress, or Arabidopsis thaliana.

Do think these folks had a clue about gene expression?

Not exact matches

The recent Lancet Breastfeeding Series refers to new discoveries being made about breastmilk — such as its role in gene expression — so it can be expected that Nestle will use the strategy of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily in epigentics research).

We don't know much about phallus evolution (external genitalia generally don't mineralize, so the fossil record is of little help), but we can compare the expression of phallus genes from organism to organism.

«We were starting to understand a lot about circuits and cells, and we had the tools to look at gene expression in different kinds of cells?

First, they did a quantitative analysis of the anatomy of related fossils and extant animals to generate a hypothesis about the transition; next, they searched for possible shifts in gene expression that correlated with the transition.

Monitoring mRNA could tell scientists a great deal about which genes are being expressed in a cell, and tweaking the translation of mRNA would allow them to alter gene expression without having to modify the cell's DNA.

However, very little is known about how the circadian clock regulates this critical part of gene expression to organize the day - night rhythm of protein expression, and if the formation of this looping changes over the day.

The tool then uses information from similar cells to make an educated guess about what the level of gene expression should be.

«Our discovery about the ROC40 protein suggests that it may be increasing the expression of genes involved in the synthesis of oil in microalgae,» Rathinasabapathi said.

Researchers have videotaped cultures in which embryos develop but found no visual pattern that hints at which cells are about to sprout, and staining for certain patterns of gene expression has been inconclusive.

To find out more about the differences between naive and primed pluripotent cells, the UW researchers first compared their gene expression profiles.

In the last 15 years, researchers worldwide have generated a large amount of information about the epigenome: proteins, factors and epigenetic markers which, when bound to DNA, regulate gene expression.

Anyone who seriously proposes that there is a force beyond gene expression, signaling molecules, differential adhesion, and those kinds of mechanisms, just doesn't know what they are talking about.

With the best - performing particles, the researchers reduced gene expression by more than 50 percent, for a dose of only 0.20 milligrams per kilogram of solution — about one - hundredth of the amount required with existing endothelial RNAi delivery vehicles.

The study also raises questions about the role of histone acetylation in regulating gene expression.

The finding could reveal much about how cells control gene activity, and also illuminate cancer, multiple sclerosis, and other diseases spurred by faulty gene expression.

The three - year study included cell culture studies at Rice as well as a detailed analysis of gene - expression profiles of more than 500 patients from the Cancer Genome Atlas and protein - expression profiles from about 200 MD Anderson patients.

Such an in - depth analysis of gene expression may help clarify the course and origin of common liver disorders, including liver cancer and non-alcoholic fatty liver disease, which affects about a fifth of the population in developed countries.

In collaboration with Prof. Ido Amit of Weizmann's Immunology Department, they analyzed the genomes of 1,500 individual liver cells, establishing patterns of expression for about 20,000 genes in each cell.

«What caught my attention about autoimmunity and specifically lupus,» Anguera said, «was that there were genes on the X chromosome that were immunity related and that had been shown to have higher expression levels in lupus patients.»

What's really impressive about Babar's accomplishment is that he did the work for both papers — one on the role of a population of stem cells in lung cancer development (published in Cell) the other on gene expression in group A Streptococcus (published in PNAS)-- as a participant in summer undergraduate research programs.

In the study, they additionally confirmed that nearby genetic variation in the form of cis - eQTLs affected expression of about 50 percent of genes in the samples.

An international consortium of researchers in the Genotype - Tissue Expression (GTEx) Consortium published findings about how genetic variation effects gene regulation in 44 human tissue types.

Microarrays allow researchers to acquire data about expression levels of thousands of genes at one fell swoop.

The tip of this ear of corn is growing abnormally, but provided scientists with information about how to tweak expression of a key gene to boost yield.

That's about an eighth of the time in which conventional cell culture methods, which rely on viral gene expression, can detect infection.

This protein is expressed in the anterior part of limb buds, and regulates the expression of a number of genes providing cells with information about their position along the anterior - posterior axis.

But in the brain, the team detected much more gene expression in humans than in chimps, whereas gene expression in the brains of chimps and the other primates was about the same.

«Gene expression patterns in the hippocampus may retain information about past locomotor activity.»

Most analytical approaches to this problem are rather rudimentary and involve calculating simple correlations among the genes whose expression changes in response to a perturbation, clustering the genes by molecular or known functional class, and drawing crude inferences about mechanism on that basis.

«We analyzed dozens of variants of this gene and quantitatively measured expression in about 1,000 embryos, creating a quantitative data set that could be used to train mathematical models, utilizing parameter optimization,» Arnosti said.

It contains data on the electrical properties of about 300 cortical neurons taken from 36 patients and 3D reconstructions of 100 of those cells, plus gene expression data from 16,000 neurons from three other patients.

Despite having tightly controlled expression levels, little is known about how miRNAs themselves are regulated because their genes are poorly defined.

When mapped to the genome, they tell us not only about the level of expression for various genes, but also which transcription start sites were used.

«We are truly excited about the RNA transcript data and the map of gene expression that we now have for 27 different organ - specific tissues», says Professor Mathias Uhlén, Program Director of the Human Protein Atlas.

From there, scientists will study the expression of Woolly Mammoth mutations to test predictions about gene function.

They also discovered that in the ripe fruit, the expression of one of these VSC - expressing genes is about 2,000 times stronger than it is in other parts of the plant.

In terms of the potential impact of the risk - associated variants, about half the risk for both disorders appears to be accounted for by variants already known to influence the expression of genes in the brain.

There were theories about how RNAi actually works to tamp down gene expression.

Genetic data combined with information on gene expression and epigenomics in relevant tissues, and clinical information, can provide clues about the effects of genetic changes within an individual's genome that increase or decrease one's risk of developing type 2 diabetes and its complications, including heart and kidney disease.

He used the GM method to make discoveries about what regulates gene expression in GM plants, and about plant transposable DNA.

Then they compared each person's transcriptome to the average transcriptome of people at the same age, intensively exploring about 100 genes whose expression were found to increase or decrease with aging.

By arraying nearly 18,000 genes on a glass chip about twice the size of a postage stamp and recording the expression patterns of those genes, researchers have obtained detailed molecular portraits of...

Finally, Yingjie Guan, assistant professor (research) of orthopaedics at Brown and Lifespan, at the COBRE for Skeletal Health and Repair, talked about her detailed work on how mechanical regulation of gene expression, for instance by the micro RNA miR - 365, affects cartilage and bone health.

Thus, Haber muses, altered cancer metabolism is not just about energy supply, but also directly affects gene expression through regulating chromatin, and that «closes the loop» between metabolism and genetics — but still poses the chicken - or - the - egg problem of which came first.

However, little is currently known about how death and the length of the post-mortem cold ischemia interval specifically affect gene expression since most existing reports are based on very few genes, tissues or individuals5, 6,7,10,11,17,18.

Genomic imprinting is a fascinating phenomenon of expression of about a hundred genes only from one parental copy.

-LSB-...] Back in December, I wrote about two studies that compared global patterns of gene expression between germ cells and somatic cells in Volvox carteri, one by Benjamin Klein, Daniel Wibberg and Armin Hallmann from the University of Bielefeld in Germany and one by Gavriel Matt and Jim Umen from Washington University in St. Louis and the Donald Danforth Plant Science Center, respectively.