Sentences with phrase «about gene function»

From there, scientists will study the expression of Woolly Mammoth mutations to test predictions about gene function.

After decades of extrapolating about gene function in trees based on gene function in a tiny, less complex plant, a team of scientists has sequenced whole genomes — determined the DNA sequence of all the genes — from 544 unrelated trees of the same species.

Not exact matches

«The key point here is that we can say something about how the gene acts to influence this behavior — that is, is by functioning as a chemical messenger in cells that control this behavior in the brain.

Video of Adam, which can originate hypotheses about yeast genes and their functions, design experiments to test the ideas and conduct the work.

Scientists estimate that about 1,000 genes are involved in the function of the healthy brain.

Steve: And there's one of the researchers you quote in the article talks about, there may be genes that are not directly responsible for some aspect of brain function even at a biochemical cascade level; there might be a gene that is responsible for the width of the birth canal and that that could be associated with ultimately with intelligence.

Manton also noted Schrödinger's use of the term code - script, but she took it to mean «the sum of hereditary material» rather than a particular hypothesis about gene structure and function.

«When you think about genes with a conserved function you think everything that gene does must be the same in all animals.

The conventional wisdom a decade or so ago was that we need about 100,000 genes to carry out the myriad cellular processes that keep us functioning.

«Little is known even about what genes distinguish one neuron from another, even though they might perform quite different functions,» Kandel says.

«We knew that Smchd1 was an epigenetic suppressor — a factor that switches off genes that are unnecessary for that particular cells» function — but we were in the dark about where and how it was acting on the DNA.»

Named after the IBM Blue Gene supercomputer it relies on, the Blue Brain Project has started modelling — in every detail — the cellular infrastructure and electrophysiological interactions within the cerebral neocortex, which represents about 80 % of the brain and is believed to house cognitive functions such as language and conscious thought.

Among the approximately 100 imprinted genes discovered so far, about half of them, including Igf2, make proteins in the brain, raising the question of whether imprinting errors in genes that control the structure and function of the brain might contribute to mental illness.

Moreover, considering that many of Arabidopsiss genes have human counterparts, knowing the locations and functions of the Arabidopsis genes will enable geneticists to locate the human genes and learn more about various disorders.

In this episode, Scientific American news editor Phil Yam discusses how veterinarians, physicians and multinational food companies need to work together in the global fight against animal - borne infectious diseases; and University of Wisconsin evolutionary biologist Sean Carroll talks about recent research tracking the evolution of yeast genes with specific functions descended from a single, duplicated gene with multiple functions.

In search of clues about the function of the two paralogs, the researchers looked for the genes across many water strider species.

Biologists are keen to sequence the nematode's genome because much is already known about the creature's molecular genetics and developmental biology — a state of affairs that should help researchers to assign functions to the genes the sequence reveals.

The site's core pages give an overview of fly development, and others list detailed information about the locations of genes in chromosomes, the structure and function of the proteins they encode, and references to the scientific literature.

Extensive research has already examined the function of microRNAs, a category of small evolutionarily conserved noncoding RNAs about 22 to 24 nucleotides in length that target protein - coding genes in a sequence - specific manner.

According to the report on the effort, which was published in the December 11 issue of Science, analysis of the worm's genome revealed 19,099 protein - coding genes — about one every 5,000 DNA bases — and 800 or so genes that have other functions.

Researchers led by Baylor College of Medicine have developed a new computational method to study the function of disease - causing genes, starting with an important new discovery about a gene associated with malaria — one of the biggest global health burdens.

In brown bears, the sequence of this gene varies from one bear to another, but all the polar bears surveyed have an identical version, with the exact same genetic code at nine variable spots in the gene, about half of which should change the function of the APOB protein.

The same discovery raises questions about the one - of - a-kind gene that features two distinct proteins that participate in two distinct functions.

[The intracellular domain's function of] transcribing a gene into a protein that then performs some function within the cell generally takes about two hours, but we were seeing leakage within 30 minutes of blocking Notch1, further suggesting that whatever process controls the permeability of the barrier is operating via a completely different mechanism,» says Bill Polacheck, Ph.D., Postdoctoral Fellow at the Wyss Institute and co-first author of the paper.

Originally, however, they were not examining brown fat thermogenesis, but instead were looking for clues to the function of ERRβ, a protein about which little was known at the time, except that it was closely related to ERRα, appeared in brown fat cells, and also worked as a so - called nuclear receptor — a molecular switch for gene activation that can be turned on by small lipophilic molecules or a signaling protein partner.

They found that 1285 loss - of - function gene variants are likely genuine, about 100 of which appear in the genome of the average European, MacArthur's team reports today in the 17 February issue of Science.

The regulation of the CAMP gene by vitamin D was discovered by Gombart, and researchers are still learning more about how it and other compounds affect immune function.

«A better understanding of the brain region and cell type - specific binding targets of Hnrnph1 will tell us more about the function of this gene and possibly identify new therapeutic strategies for minimizing risk and treating psychostimulant addiction — a disorder for which there is currently no FDA - approved drug,» explained corresponding author Camron Bryant, PhD, assistant professor of Pharmacology and Experimental Therapeutics & Psychiatry at BUSM.

What is exciting about these findings is that «now we have a handle on the genes that comprise a universal toolkit for building stomata,» Bergmann explained, «plants apparently use the same common parts, but the ways these parts function and interact with each other are different, which is both interesting from a discovery science perspective and could be harnessed to improve growth performance in grasses that humans use for food or fuel.»

Just like we test hypotheses about the functions of genes in genetic networks by knocking them out and replacing them, we need methods to selectively remove or inhibit specific microbes or metabolisms in microbial networks to determine their roles,» Brodie added.

«We want to characterize each line of mice broadly with no assumptions about what the gene is or is not doing,» said IMPC Executive Director Mark Moore, Ph.D. «If you think of the function of a gene as a needle in a haystack, we're removing the haystack so you can see what the needle does.»

Knowing the sequences, however, does not always tell us much about the function of the genes that regulate development and homeostasis.

We start with a hypothesis about a gene's function, knock it out, and see if the organism has lost that function.

Publishing in the journal Proceedings of the National Academy of Sciences the scientists report that the upregulation of the PGC - 1α gene brought about reduced biological markers of the disease and improved function in the mice.

These studies lead to an estimate of 4,000 for the number of genes whose functions are essential for viability, or about one third of the total gene number.

«The human genome sequence provided a blueprint of all the protein - coding genes in the human genome for the first time,» reveals Jan Ellenberg, Head of the Cell Biology and Biophysics Unit at EMBL Heidelberg, «this changed how we go about studying protein function.»

The Alliance brings together the efforts of the major National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)- funded Model Organism Database (MOD) groups, and the Gene Ontology (GO) Consortium, in a synergistic integration of expertly - curated information about the functioning of cellular systems.

Understanding that function would provide vital clues about the gene's potential role in T2D.

Integrating this new information into computational models, my colleagues and I predicted that about 5 percent of HARs function as noncoding RNAs, while most are enhancers that control gene expression during embryonic development.9

While not all genes with an immune function will necessarily be regulated by any specific infection, and thus an RNA - seq - based catalog of immune - related genes can not be expected to be complete, it has the significant advantage of being unbiased by assumptions about conservation of genes across species, and thus serves as a valuable starting point for comparative analysis of the evolution of immune pathways.

Dissection of these phenotypes can uncover new principles about in vivo miRNA function and genes that can influence growth and tissue patterning.

In fact, we know the functions of only about half of the genes that we detect in these communities.

Doing this will help us identify what parts of the genome actually are protein - coding genes, but it will also tell us something about those genes» functions — a gene that is strongly expressed in a leaf, but not in flowers or root tissue, is probably important for the specific functions of leaves.

These types of mice have played important roles in helping us to learn about the function of the gene on the brain.

They present their findings June 21 in the journal Nature, addressing a long - standing question about how DNA functions are organized in space and time, including how genes are regulated to be silenced or expressed.

The function of about half these genes is unknown.

Studies in mice and other animals have uncovered clues about the function of a few of the genes on chromosome 21, but many remain understudied.

About 64 percent of the genes have assigned roles in the cell, while 20 percent match other hypothetical genes with unknown function.

As more researchers identify bacterial genes with interesting functions, we can think about how to manipulate them natively for therapeutic treatments.»

And for a vegan bodybuilder who must unfortunatelly play tetris with the food sources that he choses in order to give to his body the right ammounts of aminos, restricting SPI and soy foods so much does not make his goal any easier.There are sometimes that you need a meal thats complete with aminos and soy provides that meal with the additional benefits of lacking the saturated fats trans cholesterol and other endothelium inflammatory factors.I'm not saying that someone should go all the way to 200gr of SPI everyday or consuming a kilo of soy everyday but some servings of soy now and then even every day or the use of SPI which helps in positive nitrogen balance does not put you in the cancer risk team, thats just OVERexaggeration.Exercise, exposure to sunlight, vegan diet or for those who can not something as close to vegan diet, fruits and vegetables which contains lots of antioxidants and phtochemicals, NO STRESS which is the global killer, healthy social relationships, keeping your cortisol and adrenaline levels down (except the necessary times), good sleep and melatonin function, clean air, no radiation, away from procceced foods and additives like msg etc and many more that i can not even remember is the key to longevity.As long as your immune system is functioning well and your natural killer cells TP53 gene and many other cancer inhibitors are good and well, no cancer will ever show his face to you.With that logic we shouldn't eat ANY ammount of protein and we should go straight to be breatharians living only with little water and sunlight exposure cause you like it or not the raise of IGF1 is inevitable i know that raise the IGF1 sky high MAYBE is not the best thing but we are not talking about external hormones and things like this.Stabby raccoon also has a point.And even if you still worry about the consumption of soy... http://www.ncbi.nlm.nih.gov/pubmed/21711174.