Not exact matches
Despite all this promising
research, none of the existing papers came to any definitive conclusions
about which
genes seemed to be tied to the disorder.
To clear up confusion
about the origin of the aroma
gene found in Thai Jasmine rice, scientists from the International Rice
Research Institute (IRRI) analyzed 318 varieties of aromatic rice from the International Rice Genebank, including 16 types of Thai Jasmine rice.
The recent Lancet Breastfeeding Series refers to new discoveries being made
about breastmilk — such as its role in
gene expression — so it can be expected that Nestle will use the strategy of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily in epigentics
research).
The Pew
Research Center in Washington, D.C., conducted one of the earlier surveys that revealed hesitancy, finding that 68 % of the respondents were «very» or «somewhat» worried
about gene editing.
In science news around the world, NASA's Cassini mission is
about to take its final plunge into the atmosphere of Saturn after 13 years providing an unprecedented view of the planet and its moons, a fight over whether to preserve or develop of one Europe's oldest gold mining sites heats up again, the U.S. Food and Drug Administration approves the first cancer
gene therapy for people, a U.S. court gives a green light to a $ 1 billion lawsuit brought by the Guatemalan victims and survivors of mid — 20th century syphilis experiments by
research institutions including Johns Hopkins University, and more.
Other directions for future
research, Liu said, include looking at the role of CLOCK in more forms of the disease, learning more
about exactly how CLOCK affects neural circuits to disrupt adequate inhibition of excitatory neurons, and examining whether any of the
genes that CLOCK regulates are especially important in the disorder.
In this month's issue of Genome
Research, Elizabeth Stewart and her colleagues at Stanford University present this new map, which places
about 8000 landmarks along the genome's 3 billion bases — DNA's building blocks — yielding twice the resolution of
gene maps currently in use.
Next week, the Intelligence Advanced
Research Projects Agency (IARPA), which is part of the Office of the US Director of National Intelligence, will hold a meeting
about a planned funding programme for detecting genetically modified organisms that are potentially harmful, including ones that contain
gene drives.
Readers will have at their fingertips key articles in the history of science from the late 19th through the early 21st centuries, including
research about the human genome, breast and colon cancer
genes, and the Bose - Einstein condensate in physics.
About a decade ago, O'Leary's
research group discovered that a
gene called Emx2 controlled the size of the primary visual area of the neocortex.
This will allow to understand more
about genes we currently know very little
about, and open up new avenues for
research into the genetics of human disease.
As large - scale genome sequencing projects, such as the Human Genome Project, near completion, the
research community's focus is shifting toward efforts to determine functional information
about these sequenced
genes.
A big concern
about gene patents is that they hinder genetic
research — once one company has patented a
gene, other researchers may fear infringing on that patent by conduct further
research on it, the argument goes.
Discovering what mutations mean Researchers concerned
about patent infringement may abandon
research on mutations within patented
genes, hindering progress to understand all of a mutation's effects.
«For the first time, we can predict the outcomes of modifying multiple
genes involved in lignin biosynthesis, rather than working with a single
gene at a time through trial and error, which is a tedious and time - consuming process,» says Jack Wang, assistant professor in NC State's College of Natural Resources and lead author of a paper
about the
research in Nature Communications.
The experiments set off a debate
about the safest way to do
gene drive experiments in the lab and helped prompt the Defense Advanced
Research Projects Agency and the Bill & Melinda Gates Foundation to support the academies's study.
In this episode, Scientific American news editor Phil Yam discusses how veterinarians, physicians and multinational food companies need to work together in the global fight against animal - borne infectious diseases; and University of Wisconsin evolutionary biologist Sean Carroll talks
about recent
research tracking the evolution of yeast
genes with specific functions descended from a single, duplicated
gene with multiple functions.
Now, studies of ancient DNA by two independent
research groups show what was happening to the plant's
genes middomestication,
about 5000 years ago.
The audience will learn
about the current state of breast cancer
research, how data generated by NGS
gene panels target variants of interest and have been developed and used in routine laboratory
research, and the broader issues of breast cancer education, awareness, and community services.
Extensive
research has already examined the function of microRNAs, a category of small evolutionarily conserved noncoding RNAs
about 22 to 24 nucleotides in length that target protein - coding
genes in a sequence - specific manner.
«Previous
research emphasizes people's personalities,
genes, and upbringing as the main source of moral values and disagreements
about morality,» said DeScioli.
Although previous
research has identified
genes involved with behaviors seen in eating disorders such as anorexia or bulimia, little is known
about how natural variation in these
genes could affect eating behaviors in healthy people.
What's really impressive
about Babar's accomplishment is that he did the work for both papers — one on the role of a population of stem cells in lung cancer development (published in Cell) the other on
gene expression in group A Streptococcus (published in PNAS)-- as a participant in summer undergraduate
research programs.
She also writes
about research on
gene therapy and cancer.
What
about research on patented
genes?
Dillman explained that his
research team also learned more
about gene regulation and the evolution of genomes in general as it compared the five sequences with other nematodes.
As it turns out, despite the initial skepticism
about the importance of
gene flow, modern empirical and theoretical
research using up - to - date molecular and DNA techniques have shown us not only how surprisingly far the flow of
genes between distant plant populations can be, but also that the flow of alleles among populations is just as important, if not more so in some cases, as natural selection.
The paper has split scientists, with consensus on the need for a moratorium on clinical applications but disagreement
about whether to support basic
research on editing
genes in human sperm, eggs, or embryos.
Kidney
research at the University of Virginia School of Medicine has unexpectedly led to a discovery
about the formation of the heart, including the identification of a
gene responsible for a deadly cardiac condition.
The Genetic Edge's Binns, who also published a
research paper laying claim to the myostatin finding
about a year after Hill did, says half of the 10 or so Kentucky Derby winners his company tested had two copies of the sprint version of the myostatin
gene.
The report recommends that the governing authorities, including
research institutions, funders, and regulators, develop and maintain clear policies and mechanisms for how public engagement will factor into
research, ecological risk assessments, and public policy decisions
about gene drives.
Next Wave asked: If
research on
gene vectors can be used not only to further
gene therapy but also — potentially — to aid in the development of biological weapons, should scientists be concerned
about the potential applications of their
research in genetics (as Joseph Rotblat suggested in a 19 Nov 1999 editorial in Science magazine?)
But after several questions
about potential outcomes of such early
research, Niakan did «wildly speculate» that, if certain
genes are found to be particularly important for development, one eventual approach might be to check during IVF whether eggs were making the proteins encoded by those
genes, and if not, then add them to culture media.
Gene drive
research also raises regulatory concerns
about biosafety, biosecurity, and the potential for this technology intended for human benefit to be intentionally misused for harmful purposes.
He agrees with Chénier
about the need for more
research on the spread of resistance
genes from farms to the environment.
Bengt Nordéns contribution to form a strong
research school in Gothenburg has been successful: as many as 12 out of his
about 50 former PhD students and postdocs have become professors, abroad or at other Swedish universities, and three have returned to contribute a forceful environment with their own profiles within the Department: Prof Bo Albinsson (femtosecond spectroscopy and fundamentals of electron transfer), Prof Per Lincoln (new transition - metal - based DNA ligands and statistical mechanics for
gene targeting), Prof Björn Åkerman (fundamentals and applications of DNA physical chemistry).
February 2, 2006
Gene variation increases SIDS risk in African Americans About five percent of deaths from SIDS (sudden infant death syndrome) in African Americans can be traced to defects in one gene, and half of those deaths result from a common genetic variation that increases an infant's risk of developing an abnormal heart rhythm during times of environmental stress, a research team based at the University of Chicago reports in the February 2006, issue of the Journal of Clinical Investigat
Gene variation increases SIDS risk in African Americans
About five percent of deaths from SIDS (sudden infant death syndrome) in African Americans can be traced to defects in one
gene, and half of those deaths result from a common genetic variation that increases an infant's risk of developing an abnormal heart rhythm during times of environmental stress, a research team based at the University of Chicago reports in the February 2006, issue of the Journal of Clinical Investigat
gene, and half of those deaths result from a common genetic variation that increases an infant's risk of developing an abnormal heart rhythm during times of environmental stress, a
research team based at the University of Chicago reports in the February 2006, issue of the Journal of Clinical Investigation.
Jim Thomas of the Ottawa - based ETC Group said the U.S. military's substantial funding of
gene drive
research «raises alarming question
about this entire field,» and he called the technology «powerful and dangerous,» warning that it «could have disastrous impacts on peace, food security, and the environment.»
(
Research suggests that
about 25 percent of longevity is determined by
genes.)
A different
research group recently found that the Osiris
gene cluster is under strong selection in an isolated population of the fly D. yakuba that has just begun adapting to a diet of poison - laden noni, another clue that learning more
about these
genes may be crucial for understanding OA resistance and this compelling model of ecological adaptation.
In breast cancer
research, the
gene BRCA1 has received the lion's share of attention because mutations in that
gene are responsible for
about three percent of all cases of breast cancer.
Some of the genetic factors that are being
researched right now are multiple
genes contributing to the disease (there are
about a dozen
genes that are leading candidates), and the possibility of epigenetic interactions (that is, certain
genes and other biological molecules that determine whether and when certain
genes present in the body are turned on or off) that may contribute to schizophrenia.
Read
about another example of Parksinson's
research in this other case
about the Familial Parkinson's
gene.
Vogelstein also argued that the new
research about random mutations should offer comfort to people who develop cancer despite having «near - perfect lifestyles,» as well as to parents who are worried that they somehow «gave» their children cancer, either by passing on a harmful
gene or inadvertently exposing them to an environmental toxin.
Finally, Yingjie Guan, assistant professor (
research) of orthopaedics at Brown and Lifespan, at the COBRE for Skeletal Health and Repair, talked
about her detailed work on how mechanical regulation of
gene expression, for instance by the micro RNA miR - 365, affects cartilage and bone health.
Finally, the large Drosophila
research community -
about one researcher per 2
genes - has provided a wealth of information and understanding unusual in its depth and intellectual breadth.
Professor Chris Jones talked to us
about building a world - class
research programme focused on finding the
genes that drive childhood brain tumours, and his hopes for these hard - to - treat cancers.
The Alliance brings together the efforts of the major National Institutes of Health (NIH) National Human Genome
Research Institute (NHGRI)- funded Model Organism Database (MOD) groups, and the
Gene Ontology (GO) Consortium, in a synergistic integration of expertly - curated information
about the functioning of cellular systems.
«We hope this study now provides a new cohesive direction for BRCA1
research so that we can answer the fundamental questions
about how this
gene promotes cancer and how we might be able to improve early diagnosis and, possibly, treat BRCA1 - induced cancer more effectively.»
Furthermore, the
research offers clues
about which
genes to avoid and which to target in other disease - causing bacteria.