Or your child is sick with recurrent asthma and ear infections and you want a dietary cure — you may be warned away from a highly effective therapy because members of the Nutrition Committee of the American Heart Association fail to understand basic scientific research
about human protein needs and plant foods.
Not exact matches
But in the lab, when the scientists manipulated
human cells to be able to create the water bear shielding
protein — called Dsup — they showed
about half the DNA damage as normal cells.
Charles spent years learning from experts in food and nutrition
about natural solutions to his personal health challenges and got involved in the hemp industry looking for the ultimate vegan
protein source for
humans — he found it... and much more... in the mighty hemp seed.
What
about some 2,000
proteins that are used by a
human cell as enzymes?
It makes up
about 30 % of all the
protein in the
human body, and is found in your bones, tendons, ligaments, connective tissues and skin, and plays various roles in your overall health.
In
humans, it accounts for
about 1/3 of our total
protein in our bodies and 3/4 of the dry weight of our skin.
The rice would be able to make
human proteins that could help reduce bouts of diarrhea in children by
about a day.
But when Cherr and his colleagues finally got around recently to checking out the
protein in
humans, they got a big surprise:
About a quarter of men don't make it properly because they have a mutant version of the relevant gene.
Since it shares more than 80 percent of its
proteins with
humans, studying this tiny creature can reveal many secrets
about our own biology.
These represent
about 50 percent of the total estimated number of
human protein - encoding genes.
«Since these
proteins are evolutionarily conserved from fruit flies to
humans, experiments of this type tell us a lot
about how their
human versions normally work or can go wrong.»
These retroviral gene sequences make up
about 8 per cent of the
human genome, and are part of what is called non-coding DNA because they don't contain genetic instructions to make
proteins.
«Our study indicates that this small viral
protein, Tat, directly binds to
about 400
human genes to generate an environment in which HIV can thrive.
Stanford's Snyder is pleased
about the growing push to understand
human biological variation via personal connectome and other «- ome» profiles, such as metabolomes (the total metabolites present at a given time in our bodies) and proteomes (ditto for
proteins).
Membrane
proteins make up
about one third of all
proteins in the
human body, and their malfunction is associated with more than 500 diseases.
In all, scientists estimate that the
human body contains
about 100,000 different
proteins, each the result of millions of years of evolutionary shuffling, culminating in a precise lineup of pleats, coils, and furrows required to carry out a specific job in the cell.
To track down the location of
proteins inside
human tissues, Uhlén's team of
about 100 scientists breaks the problem into two parts — finding antibodies that target individual
proteins and then using those antibodies to hunt for
proteins inside tissues.
The program works by connecting computer - generated drug profiles — including mechanisms of action, clinical efficacy, and side effects — with information
about how a molecule may interact with
human proteins in specific diseases, such as ovarian cancer.
When they added these
proteins to cultures of brain tissue from aborted
human fetuses, the tissue formed folds, as it does in
human fetuses at
about 20 weeks of gestation.
This will cover a pilot project in a small region —
about 1/1000 of the
human genome — containing the genes for the major histocompatibility complex (MHC),
proteins that present snippets of pathogens to immune cells.
In these images the horizontal green lines (dendrites marked with jellyfish green fluorescent
protein) are each
about 1 / 50ththe width of a
human hair.
In
humans, there are
about 100
proteins associated with ubiquitination, the process by which a
protein labelled with ubiquitin is removed from the cell by specific cell machinery known as the proteosome.
For example, Uhlén's initiative to map all
human proteins, the Human Protein Atlas, is now about two - thirds of the way to its goal, with plans to finish in
human proteins, the
Human Protein Atlas, is now about two - thirds of the way to its goal, with plans to finish in
Human Protein Atlas, is now
about two - thirds of the way to its goal, with plans to finish in 2015.
The
human genome contains around three meters of DNA, of which only
about two per cent contains genes that code for
proteins.
All together, the researchers found
about 37,000 mutations occurring in 10,000 clusters in the chimp and
human genomes that they think were caused by these
proteins, they report today in Genome Research.
The
human genome — the sum total of hereditary information in a person — contains a lot more than the
protein - coding genes teenagers learn
about in school, a massive international project has found.
This belief never wavered, even when geneticists realized that only
about 2 percent of the DNA in
human cells actually contains genes that make
proteins.
Scientists at the National Institutes of Health are reporting new, unexpected details
about the fundamental structure of collagen, the most abundant
protein in the
human body.
He realised there was a market for cheap copies of therapeutic
proteins such as interferon alpha, erythropoeitin, and
human growth factor — so called biogenerics — that were
about to come off patent.
The
human genome contains
about 3 billion base pairs, but only
about 2 percent of these base pairs represent
protein - coding genes, meaning that whole - exome sequencing measures the genetic alterations focused on a small but very important fraction of the genome (as opposed to techniques of whole genome sequencing, which measures every nucleotide across the entire genome, regardless of whether these genes are expressed or silent).
«
About 2 percent, or nearly 500, of all
human genes are dedicated to coding
protein kinases and over 50 percent of kinases are linked to various
human diseases.»
Each patient had
about 100 different autoantibodies in their blood, but since each patient had different autoantibodies, the 81 patients collectively had antibodies to thousands of different
human proteins.
Labs around the world have tried for years to obtain detailed images of
human GPCRs because the precise, three - dimensional arrangement of a
protein's atoms provides important details
about how a
protein interacts with its natural partner molecules in the body or with drug molecules.
The
proteins that make up the
human lens are among the oldest in the body, forming at
about 4 weeks after fertilization.
«This is an exciting new tool to answer important questions
about proteins,» Cochran said, likening µSCALE to the way that high - throughput tools for gene analysis have allowed researchers to unlock key features of biology underlying
human disease.
In mice containing transplanted
human cells carrying
about 310 GAA repeats, the prosthesis restored expression of a signaling
protein to nearly normal.
«We are truly excited
about the RNA transcript data and the map of gene expression that we now have for 27 different organ - specific tissues», says Professor Mathias Uhlén, Program Director of the
Human Protein Atlas.
Thus, for most of the
human repertoire of
about 25,000
proteins, scientists simply don't know which ones are druggable.
Joshua - Tor also collaborates with Bruce Stillman to solve mysteries
about the
human Origin Replication Complex (ORC), the «initiation
protein» for DNA replication, which Stillman's team discovered, in yeast, in 1992.
A team of researchers from Whitehead Institute and the Howard Hughes Medical Institute has revealed the structure of a key
protein complex in
humans that transmits signals
about nutrient levels, enabling cells to align their...
Proteins on the surface of both the Plasmodium sporozoite and
human host cells are likely to be important in this journey, but little is known
about the exact interactions which occur.
Some additional experiments in cells confirmed their hunch
about the physical interaction between the TDP - 43 and SCA2
proteins, but the scientists wondered whether their discovery is applicable to
humans, considering they discovered it in yeast cells.
Berkeley Lab scientists have learned new details
about how an important tumor - suppressing
protein, called p53, binds to the
human genome.
Only
about 50 of these are
human membrane
proteins — but there are several thousands in total!
Although the
human and chimpanzee genomes are distinguished by 35 million differences in individual DNA «letters,» only
about 50,000 of those differences alter the sequences of
proteins.
Steere published a paper this year
about the role of at least four autoantigens —
human proteins that can produce a major immune response under certain circumstances — that have a role in persistent joint inflammation in patients with antibiotic - refractory Lyme arthritis.
«The
human genome sequence provided a blueprint of all the
protein - coding genes in the
human genome for the first time,» reveals Jan Ellenberg, Head of the Cell Biology and Biophysics Unit at EMBL Heidelberg, «this changed how we go
about studying
protein function.»
It is estimated that the
human body alone contains
about 100,000 different
protein types, and almost all biological tasks — from digestion to immunity — occur when these microorganisms interact with each other.
Why is it so important to understand more
about human membrane
proteins?
«We are excited
about the efforts to create a
Human Cell Atlas and the addition of new emerging tools to create a knowledge - based platform for understanding the human cell» says Mathias Uhlen, Director of the international Human Protein Atlas consor
Human Cell Atlas and the addition of new emerging tools to create a knowledge - based platform for understanding the
human cell» says Mathias Uhlen, Director of the international Human Protein Atlas consor
human cell» says Mathias Uhlen, Director of the international
Human Protein Atlas consor
Human Protein Atlas consortium.