Sentences with phrase «about immune cell responses»

«My whole work is about immune cell responses to melanoma — how we can teach particular immune cells called killer T cells to recognise melanoma better, target melanoma better and kill melanoma better,» Katherine says.

Not exact matches

But about 20 years ago, researchers started noticing that the levels of cytokines and T - cells, which help drive immune responses and secrete cytokines, were higher instead of lower in blood samples from people diagnosed with depression.

«We've known about these cells blocking immune response for a decade, but haven't been able to shut them down for lack of an identified target,» said the paper's senior author, Larry Kwak, M.D., Ph.D., chair of Lymphoma / Myeloma and director of the Center for Cancer Immunology Research at The University of Texas MD Anderson Cancer Center.

If CTL019 is approved, the Swiss pharmaceutical giant plans to dole it out from about 30 preapproved sites, each trained in the multi-step process of harvesting cells, handling the product, and treating patients for the feverish and often life - threatening immune response that usually accompanies CAR - T therapy.

The researchers noticed that in highly infected mice, NK cells produced IL - 10 about 3.5 days into the infection — days later than when they'd produce IFN - gamma, a protein that helps to mount, rather than defuse, the immune system response.

Past studies have suggested that this kind of damage is associated with abnormal immune responses in the liver, but very little was known about the molecules and cells that contribute to fibrosis.

She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.

Immune Design is a clinical - stage biotechnology company made up of collaborative, «can do», experienced professionals passionate about leveraging the company's leading - edge technologies that target dendritic cells for a more precise immune response for the treatment of cancer and other chronic conditions.

«The observed increase in the ratio of cytotoxic CD4 T cells to CD4 helper T cells indicates that they are an important component of the protective immune response to viral infections and that their induction should be an important marker for successful vaccinations against certain viral diseases,» says postdoctoral researcher and first author Veena Patil, Ph.D. «But we really didn't know enough about their molecular profile and the mechanisms that drive their differentiation and maintenance.»

We applied this to the single - cell RNA - seq data of the immune cells in our study, to learn about the bifurcation of cell types happening during the malaria immune response.