I am curious
about the mechanism involved when the CO2 cools.
Not exact matches
Even so, in deploying the «envisage» or «entertain,» nothing definite is said
about the non-conjunctive
mechanism involved in the primordial act of holding - together - without - bringing - into - overarching - unity.
The detailed sequence of elementary steps (
about twenty) which must be
involved in the B - Z reaction has been worked out by Richard Noyes.11 This
mechanism (called «the Oregonator» in honor of the location of Noyes's laboratory) is well understood and
involves nothing but ordinary chemistry, but it is too
involved to discuss here.
Unfortunately, our descent was interrupted unexpectedly by — and the party
involved shall remain nameless for perpetuity, though by now everyone we know knows all — the wedging of a Croc, which this party was wearing, into the
mechanism of the escalator
about two - thirds of the way down.
Researchers still have much to learn
about the imprinting process and the genes
involved, Zhang says, but the discovery of a second
mechanism for silencing one copy of these genes underscores imprinting's importance.
But much
about quorum sensing remains to be discovered; scientists are still trying to uncover the molecules and
mechanisms involved, and figure out how they operate outside the laboratory.
Professor Peter Kraft at Harvard TH Chan School of Public Health, USA, says: «Given the size of these studies, we expected that we would find a lot of new breast cancer risk variants, but the studies tells us a lot more
about which genes are
involved, revealing many previously unsuspected genes and genetic
mechanisms underlying breast carcinogenesis.
In other disease areas, the Parkinson's disease map and the Atlas of Cancer Signalling Network, have already begun the process of integrating knowledge
about the
involved mechanisms in order to understand the different subtypes of these diseases.
The new information is «a big piece of the puzzle that was missing» and it neatly confirms scientists» predictions
about how lunge feeding scales with baleen whale body size, says Robert Shadwick, a comparative physiologist who studies whales» feeding
mechanisms at the University of British Columbia, Vancouver, in Canada, and was not
involved in the research.
«Although we demonstrated that BCG educates stem cells to generate trained immunity, we had no idea
about the molecular
mechanisms that were
involved in this protective pathway,» says Dr. Divangahi, who is also an Associate Director of the Translational Research in Respiratory Diseases Program at the RI - MUHC and an Associate Professor of Medicine at McGill University.
Most analytical approaches to this problem are rather rudimentary and
involve calculating simple correlations among the genes whose expression changes in response to a perturbation, clustering the genes by molecular or known functional class, and drawing crude inferences
about mechanism on that basis.
In this new paper, the researchers reveal more
about that
mechanism, showing that without the protective ability of BRCA1, breaks in the DNA strands go unfixed, prompting the molecule ATM kinase to activate a cellular «suicide» pathway
involving a protein called p53.
«We know relatively little
about the behavioral or ecological
mechanisms that allow these induced defenses to be effective,» says Richard Karban, an ecologist at the University of California, Davis, who was not
involved in the work.
Moreover, PHENONIM - ICS is
involved in European projects presenting a strong impact on human health: Interreg CARDIOGENE (Genetic
mechanisms of cardiovascular diseases), GENCODYS (Genetic and epigenetic networks
involved in cognitive dysfunctions), AgedBrainSYSBIO (Basic studies of brain aging), as well as projects in partnership with industry: MAGenTA (an Industrial Strategic Innovation project supported by Bpifrance
about the treatment of major urogenital diseases) and CanPathPro (H2020 program), to develop a predictive modeling platform of signaling pathways
involved in cancers.
Uterine leiomyomas, also called fibroids, cause a very significant burden to women's health but relatively little has been known
about the
mechanisms of tumorigenesis
involved.
«Understanding the
mechanisms involved in regulating insulin is important and therefore helps us to better understand the pathophysiology of diabetes,» says Claret, who emphasizes that «much research needs to be done to apply these findings, given that we are talking
about neural
mechanisms of complex intervention.»
«These results suggest that phytoestrogens can interfere with the normal estrogen feedback
mechanisms with respect to release of gonadotropin in the ewe... although most studies into the effects of phytoestrogens have concentrated on changes in the reproductive tract, there are indications that they interfere with the hormone balance between the ovaries and the hypothalamo - adenohypophysical system... ewes on phytoestrogens have shown follicular abnormalities such as numerous small follicles, deficient antrum formation and signs of early atresia... it is possible that the permanent changes brought
about by phytoestrogens in the brain are a result of these compounds interacting with estrogen receptors in this tissue, and subsequently influencing the re-synthesis or replenishment of cyto - plasmic estrogen receptors... phytoestrogens can interfere with the delicate feedback
mechanisms involved in the release of the gonadotrophins.»
Eventually, when we know more
about the effects of the
mechanisms involved, fluctuations in cosmic rays could be incorporated in helping model cloud albedo changes.
A point I have been trying to get across is that it's not
about believing in AGW, it's
about understanding the
mechanisms involved.
Please be precise
about the
mechanisms, volumes and timescales, just saying ocean circulations is not good enough, given what we know
about the very long timescales
involved to move the water.
A lot of people have different positions in the AGW debate, and with so many people and so much uncertainty particularly
about the
mechanisms and rate constants of all of the kinetic processes
involved, I find it implausible that people would waste time on the simple comparisons, making much sound and fury, when it starts out with a short term comparison of CO2 and temperature over the same last few years.
They come up with all kinds of hypothetical feedback
mechanisms involving more natural aerosol emissions in response to global warming: Dimethylsulfide from marine phytoplankton (although a very intriguing possibility, this has never been confirmed to be a significant feedback
mechanism, and there is ample evidence to the contrary, which is omitted from the report), biological aerosols (idem), carbonyl sulfide (idem), nitrous oxide (idem), and iodocompounds (idem),
about which they write the following: «Iodocompounds — created by marine algae — function as cloud condensation nuclei, which help create new clouds that reflect more incoming solar radiation back to space and thereby cool the planet.»
«[T] he science to me — and I have been
involved, not as a scientist but as a lawyer — the science to me suggests, in the ten years I've been
involved in it, that there is no basis, no
mechanism that anybody can point to or look at to say that more CO2 in the air is going to lead to catastrophic global warming or apocalyptic global warming, as opposed to some mild warming, which is nothing to be concerned
about at all.
Another meta - analysis reached similar conclusions
about the equivalence of CBT and BT1 and a recent large - scale clinical trial of BT showed that it was as effective as antidepressant medication for depression.3 While BT and CBT were equally as effective for lower - levels of depression severity, patients with severe depression specifically benefited more from BT than CBT.3 Behavioural activation, which
involves graded activity and goal scheduling, is the central component of BT for depression and may be related to a more general
mechanism of change that is operating in many different treatments for depression, especially CBT.
Membership in a single - parent family or stepfamily is associated with increased levels of significant behavioral, emotional, and academic problems in children.1, 2 The
mechanisms underlying this connection are likely to
involve, among other factors, financial adversity, increased stress directly related to family transitions, and increased exposure to additional psychosocial risks.3, 4 Compared with the extensive research base connecting family type (ie, membership in a 2 - parent biological family, stepfamily, or single - parent family) and children's psychological adjustment, little is known
about the physical health consequences of membership in diverse family types.
These questions can be divided into three categories: (1) questions
about cross-sectional specificity, (2) questions
about longitudinal specificity, and (3) more complex questions
about developmental specificity, which
involve questions
about bidirectional associations and possible
mechanisms for the aggravation of difficulties.