«I now give regular lectures
about cell line contamination,» says Ain, «and every last person in the audience is shocked and horrified.
The registry allows searching for cell lines and for information available
about these cell lines.
Not exact matches
Honda established a division late last year to develop electric vehicles (EVs) as part of its long - held goal for lower - emission gasoline hybrids, plug - in hybrids, EVs and hydrogen fuel
cell vehicles (FCVs) to account for two - thirds of its
line - up by 2030, from
about 5 percent now.
As a cancer researcher, do you think the mechanisms of tumor growth are somehow changing to come into
line with your perceptions, or is it possible that the process of our learning more
about DNA mutations and
cell architecture and nutrient exchange and epigenetic effects make it possible for us to inch ever closer to understanding that which is already going on under our noses?
The interesting thing
about it is the revertant
cell lines that keep cropping up.
For example, in 2011, I wrote a post
about impoverished students here in Houston being photographed with
cell phones in the lunch
line and shamed by their peers on social media.
But when I asked this question yesterday at our Food Services Parent Advisory Committee meeting, I learned that not only does stigma remain a real issue at some schools, there's now a troubling, modern - day twist on the problem: on some campuses, hapless kids standing in the federally reimbursable meal
line are having their pictures taken by other students»
cell phones, with the photos then uploaded to Facebook and / or texted around the school along with disparaging messages
about the child's economic status.
Speaking of
cell phone connectivity, what
about home security systems that don't rely on electricity or telephone
lines?
«Didn't seem to have a good response to the question
about his previous experience with our
cell line.
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Nevertheless, Vallier is concerned
about the number of changes in the reprogrammed
cell lines.
About three - fourths of the stem
cell lines were found to be unsuitable for research, and many if not all the
lines were contaminated with mouse feeder
cells.
Stick - on solar
cells about to flop off the production
line could revolutionise the business of generating electricity from sunlight
But the bottom
line is that
about two thirds of all T
cells reside in the lymphoid tissue of the gut, where the virus spreads after exposure, even before it shows up in blood.
The work, funded by the US National Human Genome Research Institute, aims to create human
cell lines with subtly different genomes in order to test ideas
about which mutations cause disease and how.
Another problem is that in its July 2009 Guidelines on Human Stem
Cell Research, NIH spelled out specific requirements
about embryo donation for newly derived
lines, says Pilar Ossorio, a legal scholar who studies research ethics at the University of Wisconsin Law School.
When they think
about how
cells put together the molecules that make life work, biologists have tended to think of assembly
lines: Add A to B, tack on C, and so on.
«I got most excited
about it when George brought his idea of virus - resistant mammalian
cells on the table, and the idea of an ultrasafe
cell line, which could be a relatively short - term win,» Boeke says.
In testing on two mouse
cell lines, the drug combination reduced the viability of cancer
cells by
about 50 percent when compared with everolimus alone, according to the findings.
Intestinal stem
cells are particularly important because a new intestinal
lining is generated
about every 4 - 5 days.
«This is an important and fundamental paper for understanding human germ -
line cells and finding the basic information
about human germ -
cell biology,» says reproductive biologist Evelyn Telfer of the University of Edinburgh, UK.
«The beautiful thing,» Lanza says, «is that if you have an embryonic stem
cell line that is O negative, because it's immortal you could create an unlimited amount of universal blood that would match virtually everybody, so you wouldn't have to worry
about matching blood types.»
Studies in diabetic rodents suggest that diabetes may alter the intestine's mucosal
lining, which is maintained and regenerated by intestinal stem
cells; however, little is known
about how this occurs and whether it is relevant to humans.
In the chamber, tubes
about the thickness of a human hair were
lined with endothelial
cells as in natural blood vessels.
The case raises important questions
about privacy and consent in
cell line research — questions for which there are as yet no answers.
The challenge, he says, will be figuring out how to force the transition from progenitors to stem
cells, which spontaneously occurred in
about one third of testicular
cell lines.
Six years ago, President Bush limited federally funded research to
about 20 viable
lines of
cells that had been extracted from embryos prior to August 9, 2001.
«While we expected to find some mutations in stem
cell lines, we were surprised to find that
about five percent of the stem
cell lines we analyzed had acquired mutations in a tumor - suppressing gene called p53,» said Merkle.
Researchers running clinical trials planned to stop enrolling new patients, and furloughs were scheduled for all but
about a quarter of NIH's 19,000 staff members, who were deemed «essential» to care for patients and maintain animals and
cell lines.
Knowing more
about the activation process has led researchers to be able to induce greater vulnerability by cancer
cells to an existing first -
line treatment for cancers (mainly lung) driven by a receptor called EGFR.
But they also warn that their work shows the danger of drawing general conclusions
about cancer - relevant phenotypes from a single cancer
cell line.
Lutz and Falkowski cite one study where unique chemical compounds isolated from an actinomycete strain inhabiting deep - sea sediments
about 3.3 kilometers down in the South China Sea have shown potent activities against three cancerous tumor
cell lines and also showed antibacterial activities.
All human
cell lines growing in tissue culture dishes, and
about 95 % of
cells in a human being, split evenly, resulting in daughter
cells of equal size.
Biologists who study the mechanics of
cell division have for years disagreed
about how much force is at work when the
cell's molecular engines are
lining chromosomes up in the
cell, preparing to winch copies to opposite poles across a bridge - like structure called the kinetochore to form two new
cells.
During the next five years, KOMP2 will transform the knockout mouse embryonic stem (ES)
cells into adult mice for 2,500
lines of well - characterized knockout mice strains, and IMPC will create
about 2,500 additional knockout mouse strains.
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He added: «Truly naive human ES
cell lines would not only help answer fundamental questions
about how we are made, and be useful for drug screening and tissue therapy, but they would also provide a benchmark against which other types of stem
cells could be measured in terms of their effectiveness in stem
cell therapy and regenerative medicine.»
Then after four days, the Read more
about Immune
cells help the brain
lining heal after head injuries - Scimex
The team then selected
cells from these organoids and placed them inside the Intestine - Chips, which are
about the size of AA batteries and re-create the natural microenvironment of the human intestine, including the intestinal epithelium — the layer of
cells that forms the
lining of both the small and large intestines.
Such an immunological exemption could alleviate many concerns
about using
cells for therapy that don't exactly match the recipient's immune system - such as existing embryonic stem
cell lines that are not directly derived from the recipient.
Each Organ - Chip, which is composed of a clear flexible polymer, is
about the size of a AA battery and contains tiny hollow channels
lined with living
cells.
As names are not even used consistently in publications and deviations from the original name are not rare, the situation increasingly causes confusion
about the identity of
cell lines used in specific studies.
This is the route our project is pursuing, but it may take several years to establish a cultured
cell line; bird primordial germ
cells are quite finicky
about living outside of a bird's body.
Wolin and her colleagues had begun to answer questions
about Ro's function when their earlier experiments demonstrated that the Ro protein binds to small RNA molecules that are misfolded versions of those that help make up the
cell's ribosomes, which are its protein assembly
lines.
Despite the long
lines outside of technology stores anytime a new gadget is released, there was a time not so long ago when people in the United States actually went
about their days minus
cell phones, personal computers, electronic readers and televisions.
The goal was to deepen the knowledge
about the pharmacological and cytotoxic effects of the drug Temodex in vitro in different human brain cancer
cell lines.
Learn more
about these constructs and the
cell lines they've been used to create in the Allen Institute ’s
Please contact Rockland directly
about acquiring our melanoma
cell lines by contacting Rockland customer service for help with
lines not found yet on their website.
About 9 out of every 10 kidney cancers are renal
cell carcinomas — cancers that form in the
lining of the tubules inside the kidney.
In essence, the signers were trying to get the President to change his mind
about stem
cell lines used for research so that Congress does not have to create a legislative solution.