Examining expression levels of H2AX in breast cancer tumor data from The Cancer Genome Atlas, a large National Institutes of Health database containing genetic information
about tumor tissue from more than 11,000 patients, the Roswell Park team found that breast cancer patients whose tumors had high levels of H2AX had a significantly worse prognosis than those with low levels.
After surgical removal, the metabolic processes in a tumor change in a very short period of time, so that valuable information
about the tumor tissue is lost during a conventional sampling procedure.
Not exact matches
Although there have been great advances made in the treatment of leukemias and other cancers, little is known
about how Glioblastomas are formed and how these
tumors infiltrate the brain
tissue.
About 350 new cases of rhabdomyosarcoma are identified each year in the U.S., making it the most common soft
tissue tumor in children.
«
About five percent of people have some kind of cartilage
tumor in their bones, and in most cases it's because the growth - plate cartilage cells weren't fully replaced by bone
tissue,» Alman said.
Together they are being used to peer into the microenvironment of
tumors and other
tissues while learning
about the co-registration of multiple lines of imaging data.
Doctors already test breast
tumors for Ki67 levels, which can inform decisions
about treatment, but this is the first time scientists have been able to link Ki67 to precancerous
tissue and use it as a predictive tool.
The tool sprays a microscopic stream of charged solvent onto the
tissue surface to gather information
about its molecular makeup and produces a color - coded image revealing the nature and concentration of
tumor cells.
«The edge of a
tumor is more challenging to detect than cancer versus healthy
tissue due to a mix of different
tissue types, and it is the edge that surgeons want to know
about,» Ramanujam says.
A few years ago Peperstraete stumbled on an article in a science journal
about medical researchers using crossed laser beams to image and heat
tumors in a patient without disturbing any of the surrounding
tissue.
«We are talking
about fast - growing
tumors that invade normal brain
tissue and are very difficult to treat,» said Orin Bloch, MD, a neurosurgeon at Northwestern Memorial Hospital and lead author of the study.
It is presently possible to differentiate
about 100 types of CNS
tumors based on
tissue characteristics.
A three - minute film
about a tiny molecule that lights up brain
tumors so neurosurgeons can better distinguish cancer from normal
tissue has a chance for its own moment in the spotlight in the Sundance Film Festival in January.
Whereas the
tumor is in constant competition with the surrounding
tissue, little is known
about the mechanics of this interaction.
The T denotes information
about the
tumor itself, including the size or whether it has invaded any nearby
tissue.
Sorenmo's Canine Mammary
Tumor program at the University of Pennsylvania's Ryan Veterinary Hospital, in partnership with Princeton University, has now enrolled about 145 «underdogs,» offering them needed surgeries, collecting tumor tissue for the ongoing genomic studies, and placing them in new homes that will help with follow - up rese
Tumor program at the University of Pennsylvania's Ryan Veterinary Hospital, in partnership with Princeton University, has now enrolled
about 145 «underdogs,» offering them needed surgeries, collecting
tumor tissue for the ongoing genomic studies, and placing them in new homes that will help with follow - up rese
tumor tissue for the ongoing genomic studies, and placing them in new homes that will help with follow - up research.
There are three grades: Grade I
tumors are easily identified and rarely metastasize; Grade II
tumors have intermediate differentiation and extend deeper into the underlying
tissues and
about 20 percent will spread or metastasize; Grade III
tumors are poorly differentiated and behave aggressively with an 80 percent or higher chance of metastasis.
However, the basic thing
about stage three is that the cancer has moved beyond the first region of the initial
tumor and is probably in the lymph nodes or other nearby
tissue.
Philadelphia, PA
About Blog The Children's Brain
Tumor Tissue Consortium is committed to discovering new cures and better therapies for children with pediatric brain
tumors.