Diagnosis
of canine dirofilariosis in animals which originate from a low - endemic region is difficult for 3 main reasons: 1) possible
absence of circulating
microfilariae (occult disease), 2) high frequency
of a low number
of adults, which in turn produces false negative results, using either ELISA or latex agglutination test, 3) possible false sero - positive results, due to cross-reaction with adult antigens
of Dirofilaria (Nochtiella) repens (Schrey, 1996), the agent
of subcutaneous dirofilariasis causing chronic pruritic dermatitis in dogs (Tarello, 1999).
Clinical re-examination and a Knott test, carried out 1 month after the completion
of treatment, showed the resolution
of the cutaneous lesions and the
absence of Dirofilaria repens
microfilariae in the blood.