Sentences with word «acamprosate»

Most studies assessed acamprosate (27; n = 7,519), naltrexone (53; n = 9,140), or both.

The NNT to prevent return to any drinking for acamprosate was 12 and was 20 for oral naltrexone (50 mg / d).

These include acamprosate or naltrexone in the treatment of alcoholism, or methadone or buprenorphine maintenance therapy in the case of opioid addiction.

Consequently pharmaceutical companies have produced GABA agonists such as acamprosate to prescribe to people suffering form alcohol addition.

Method: In this 10 - week, randomized, placebo - controlled, flexible dose trial, 40 outpatients with BED received acamprosate (N = 20) or placebo (N = 20).

Conclusion: Although acamprosate did not separate from placebo on any outcome variable in the longitudinal analysis, results of the endpoint and completer analyses suggest the drug may have some utility in BED.

Objective: To assess preliminarily the effectiveness of acamprosate in binge eating disorder (BED).

Results: While acamprosate was not associated with a significantly greater rate of reduction in binge eating episode frequency or any other measure in the primary longitudinal analysis, in the endpoint analysis it was associated with statistically significant improvements in binge day frequency and measures of obsessive - compulsiveness of binge eating, food craving, and quality of life.

He also tried naltrexone and acamprosate, the only two drugs approved by the U.S. Food & Drug Administration to treat alcohol dependency, without success.

«Drugs currently used for AUDs (alcohol use disorders)-- acamprosate, naltrexone and disulfiram — have limited success — so this is a ground - breaking development with enormous potential,» said Professor Bartlett who is based at the Translational Research Institute.

An analysis of more than 120 studies that examined the effectiveness of medications to treat alcohol use disorders reports that acamprosate and oral naltrexone show the strongest evidence for decreasing alcohol consumption, according to a study in the May 14 issue of JAMA.

Because of its long - standing availability (from the 1950s), clinicians may be more familiar with disulfiram than naltrexone or acamprosate.

By identifying 4 effective medications for AUD [naltrexone, acamprosate, topiramate, and nalmefene], the authors highlight treatment options for a common medical condition for which patient - centered care is not currently the norm.

The acamprosate, naltrexone, and their matching placebos used in this study were donated by Lipha Pharmaceuticals.

Review: in alcohol use disorders, acamprosate is more effective for inducing abstinence while naltrexone is more effective for reducing heavy drinking and craving

Among completers, weight and BMI decreased slightly in the acamprosate group but increased in the placebo group.