These results reveal that aneuploidy induced by transient centrosome amplification can
accelerate tumorigenesis in p53 - deficient cells.
We also demonstrated that this observation was not caused incidentally by a particular vectoring system: using intraductal injection of a lentiviral vector (Bu et al., 2009) to introduce caErbb2 to ductal epithelia, we also observed
accelerated tumorigenesis in the parous group relative to the virgin group (Figure 1 — figure supplement 2).
Not exact matches
«This study demonstrates the significance of mammalian iRhoms in regulating an EGFR signaling event that promotes
accelerated wound healing and triggers
tumorigenesis,» Shultz says.