Sentences with phrase «accelerated aging as»

The effect of the water is to drip through the sculptures in the gallery, warping and degrading them in an imposed process of accelerated aging as the exhibition progresses.

However, many of us are experiencing accelerated aging as a result of systemic chronic inflammation also referred to as «inflammaging».

The primary culprit is a greenhouse gas called PM2.5, which accelerates aging as much as UV rays.

Not exact matches

In his article «The Age of Secular Stagnation,» Larry Summers argued that excess of saving over investment is acting as a drag on demand to weigh on growth and inflation, and current monetary stimulus should be expanded to accelerate investments and pull demand forward, such as raising the inflation target or to conduct nominal GDP targeting.

The vast movements among the outcastes of India, with the demands for the lightening of their age - long disabilities, while reaching far outside the Christian communities, have undoubtedly been accelerated and possibly have had as a major source the ideals and hopes which have issued from Christianity.

«Too much sugar in your diet will lead to an age accelerating process in your body known as glycation and glycation does damage to the collagen in your skin making you lose skin elasticity causing wrinkles to appear,» affirms Dr. Calapai.

In the early»90s, Bartke wrote a grant application proposing to study the giant, growth - hormone - flooded mouse as an example of accelerated aging.

«The human genes and pathways that Tat manipulates correlate well with symptoms observed in these patients, such as immune system hyperactivation, then weakening, and accelerated aging,» Dr. D'Orso said, describing the situation in which HIV infection leads to AIDS.

Fat accelerates aging After examining 1,122 adult women, molecular biologist Tim Spector of St. Thomas» Hospital in London concluded that extra pounds can age white blood cells as much as 8.8 years.

He runs a group called the Society for the Rescue of Our Elders, meant to accelerate and raise funds for aging - reversal research, as well as an online business that sells «life extension» supplements.

While everyone's telomeres dwindle as they grow older, a big split occurs after age 50, when telomere shortening among men accelerates.

But for those who specialize in the long view, fertility collapse and accelerated aging have supplanted overpopulation as the most salient demographic trend.

Using sediment gathered from the ocean floor in different areas of the world, the researchers were able to confirm that as the ice sheets started melting and the climate warmed up at the end of the last ice age, 18,000 years ago, the marine nitrogen cycle started to accelerate.

As part of this global effort to realize better treatments for age - related conditions, a group of scientists from the department of restorative dentistry, University of Malaya and four other universities in the US have recently reported a major success in developing new biomedical implants with the ability to accelerate bone healing.

There is currently no treatment, and accelerated ageing means these children suffer from conditions normally characteristic of old age, such as heart disease and diabetes, and often die around 13.

«These findings do not speak to whether accelerated aging is specific to PTSD, but they do argue the need to re-conceptualize PTSD as something more than a mental illness,» said first author James B. Lohr, MD, professor of psychiatry.

The reason could be that plant defenses against pathogens gradually weaken after a fire, Moritz and Odion speculate — for instance, from stiffer competition among plants as they grow, decreased chemical defenses as they age, or depletion of soil nutrients.The findings suggest that California's fight against forest fires over many decades may have precipitated or accelerated the outbreak, and that perhaps controlled burning could be used to halt it, the authors say.

And the trend will only accelerate as the global population ages and sedentary lifestyles and unhealthy food become more common around the world.

«Negative fateful life events and the brains of middle - aged men: Findings suggest common major midlife adverse events, such as divorce or death of a family member, accelerates aging in the brain.»

Writing in the journal Neurobiology of Aging, a research team, led by senior author William S. Kremen, PhD, professor of psychiatry and co-director of the Center for Behavior Genetics of Aging at UC San Diego School of Medicine, found that major adverse events in life, such as divorce, separation, miscarriage or death of a family member or friend, can measurably accelerate aging in the brains of older men, even when controlling for such factors as cardiovascular risk, alcohol consumption, ethnicity and socioeconomic status, which are all associated with aging Aging, a research team, led by senior author William S. Kremen, PhD, professor of psychiatry and co-director of the Center for Behavior Genetics of Aging at UC San Diego School of Medicine, found that major adverse events in life, such as divorce, separation, miscarriage or death of a family member or friend, can measurably accelerate aging in the brains of older men, even when controlling for such factors as cardiovascular risk, alcohol consumption, ethnicity and socioeconomic status, which are all associated with aging Aging at UC San Diego School of Medicine, found that major adverse events in life, such as divorce, separation, miscarriage or death of a family member or friend, can measurably accelerate aging in the brains of older men, even when controlling for such factors as cardiovascular risk, alcohol consumption, ethnicity and socioeconomic status, which are all associated with aging aging in the brains of older men, even when controlling for such factors as cardiovascular risk, alcohol consumption, ethnicity and socioeconomic status, which are all associated with aging aging risk.

It usually causes no symptoms until middle or older age but as narrowing and hardening of the arteries accelerates, they choke blood flow, causing pain and other serious cardiovascular complications.

Progeria, also known as Hutchinson - Gilford Progeria Syndrome (HGPS), is a rare, fatal genetic disease characterized by an appearance of accelerated aging in children.

Accelerated production of GH is bad, it activates excessive insulin IGF - 1 axis which increases T2D, reduces SIRT / DAF / FOXO genes who activate important oxidative stress genes (SOD, NRF2...)- But LOSS of GH is just as bad Hutchison - Guilford»S progeria children who die at 11 to 15 years old have an extreme accelerated aging (they look like children with ghastly «dying look» of very old people Accelerated production of GH is bad, it activates excessive insulin IGF - 1 axis which increases T2D, reduces SIRT / DAF / FOXO genes who activate important oxidative stress genes (SOD, NRF2...)- But LOSS of GH is just as bad Hutchison - Guilford»S progeria children who die at 11 to 15 years old have an extreme accelerated aging (they look like children with ghastly «dying look» of very old people accelerated aging (they look like children with ghastly «dying look» of very old people phenotype).

Dr. Gudkov continued, «Recognizing SAMs as a cellular target of aging allowed us to timely redirect our effort from senolytic to «SAMolytic» drugs and to accelerate the development of novel anti-aging therapeutics.»

Cardiovascular disease and renal disease for example are accelerated in patients with diabetes and AGEs have been shown to induce senescence in cell types related to these diseases, such as endothelial progenitor cells, vascular endothelial cells and renal cells.

(8) Imputation of these results specifically to the animals» age - related, low - BubR1 - driven rise in p16Ink4a - expressing senescent cells was, however, limited: limited by the very nature of so - called «accelerated aging» models such as BubR1H / H, (9) and limited by the lifelong, global absence of p16Ink4a expression in the backcrossed mice.

The European Alps have been growing since the end of the last little Ice Age in 1850 when glaciers began shrinking as temperatures warmed, but the rate of uplift has accelerated in recent decades because global warming has sped up the rate of glacier melt, the researchers say.

This means no diabetes in Bowhead whales, obviously since diabetes is accelerated aging of the ECM, such as species pentosidine accrual age curves show and same thing for crosslinks like glucosepane.

For example, beluga whales live rough 50 some years, they are short - lived whales, some of them get type II diseases and as such, show diabetic human - like features of accelerated collagen crosslinking by AGEs production during glycation / glycoxidation to their hyperglycemia.

What is particularly interesting is that AGEs have been shown to induce premature cellular senescence, suggesting that high glucose levels associated with diabetes likely accelerates ageing in other tissues that consequently manifest as disease.

Impaired functioning of telomeres can lead to genomic instability, and so to cancer, as well as accelerate the aging process.

Further, this enlargement, present as early as 3 years of age, appears to represent accelerated growth in infancy and may be followed by slowed growth in late childhood.

Fabienne Lucas, MD PhD The Ohio State University Wexner Medical Center Columbus, OH Transplant as a Model for Accelerated T - Cell Aging

It can cause uneven skin tone and loss of collagen as well as accelerated skin aging.

Cortisol levels rise with rigorous exercise, such as running, which may cause too much wear and tear and accelerate aging.

In turn, low levels of BDNF are linked to poor neural development, Alzheimer's, neurotransmitter dysfunction, psychiatric disorders such as clinical depression and schizophrenia and accelerated aging.

After adjusting for education levels, the researchers found that scores in all areas except vocabulary dropped in all age groups during the study, with the declines accelerating as people got older.

Low levels of glutathione have been linked to chronic conditions such as Alzheimer's, heart disease, chronic fatigue syndrome, diabetes and accelerated aging.

Dr White and colleagues showed that men and women who ate tofu at least twice per week experienced accelerated brain aging, diminished cognitive ability and were more than twice as likely to be clinically diagnosed with Alzheimer's disease.

It is linked to infertility, menstrual problems, accelerated aging, allergies and autoimmune problems as well as nutrient deficiencies, sleep problems and even some types of cancers.

Natural HGH production declines after puberty, and the rate of decline accelerates as the person ages (environmental and lifestyle factors exacerbate this decline)-LSB-...]

As you might expect, poor dietary habits are also linked with accelerated aging.

The more minerals you lose, the greater the risk becomes for conditions such as osteoporosis, coronary artery disease, high blood pressure and a long list of degenerative diseases which are associated with low oxygen and mineral levels such as accelerated aging.

Aging - associated increases in oxidative damage to key enzymes results in their structural deformation and decreased binding affinity for the co-enzyme, causing a decrease in enzyme funtion.8 Ames» research has demonstrated that increasing the availability of acetyl L - carnitine and α - lipoic acid, two nutrients that serve as mitochondrial enzyme co-factors, restores the velocity of the reactions (KM) in the related enzymes, and thus restores aging mitochondria's ability to produce youthful levels of ATP.9 10 11 12 13 Part II focused on the inter-relationships among the folate, methylation and transsulfuration pathways, whose dysfunction results in increased free radical production coupled with disruption of glutathione (GSH) synthesis, thus accelerating mitochondrial decay and aAging - associated increases in oxidative damage to key enzymes results in their structural deformation and decreased binding affinity for the co-enzyme, causing a decrease in enzyme funtion.8 Ames» research has demonstrated that increasing the availability of acetyl L - carnitine and α - lipoic acid, two nutrients that serve as mitochondrial enzyme co-factors, restores the velocity of the reactions (KM) in the related enzymes, and thus restores aging mitochondria's ability to produce youthful levels of ATP.9 10 11 12 13 Part II focused on the inter-relationships among the folate, methylation and transsulfuration pathways, whose dysfunction results in increased free radical production coupled with disruption of glutathione (GSH) synthesis, thus accelerating mitochondrial decay and aaging mitochondria's ability to produce youthful levels of ATP.9 10 11 12 13 Part II focused on the inter-relationships among the folate, methylation and transsulfuration pathways, whose dysfunction results in increased free radical production coupled with disruption of glutathione (GSH) synthesis, thus accelerating mitochondrial decay and agingaging.

As a high - impact sport, running can be hard on the joints and connective tissue and may accelerate the aging process.

A 2016 study found that toxic fumes in the air cause premature aging by accelerating wrinkles and age spots and worsening skin conditions such as eczema and hives (8).

As you age, the LDL receptors are damaged, but this damage is accelerated in various diseases, such as diabeteAs you age, the LDL receptors are damaged, but this damage is accelerated in various diseases, such as diabeteas diabetes.

When consumed in excess, sugar acts as a toxin and drives multiple disease processes in your body, not the least of which is insulin resistance, a major cause of accelerated aging.

Various hypotheses have been put forward to explain the molecular reasons for aging, a prominent role among them being played by the free radical theory of aging.3, 4 Free radical components (reactive oxygen species or ROS) or lipid peroxide (LPO) is involved in the pathogenesis and progression of accelerated skin aging and chronic skin conditions such as acne vulgaris.

It is worth repeating; if you eat a non-fiber carbohydrate (sugar or starch), it will raise your blood sugar, as it would your neighbor's blood sugar, and it will raise virtually every person's blood sugar in the world... and every dog's, and every worm's blood sugar... In turn, raising glucose raises insulin and leptin and accelerates the rate of aging, and the symptoms of aging, including cardiovascular disease, diabetes, obesity, osteoporosis, and cancer.