Sentences with phrase «accumulating cellular proteins»
For example, inflammation in brain tissue caused by either genetic susceptibility or triggered by accumulating cellular proteins and external events, such as severe concussions, will leave the brain more open to injury.
https://www.mcleanhospital.org/ Not exact matches
Calcium, however, puts a strain on cells — it is known to hinder protein - folding and metabolism when it accumulates — disrupting normal cellular function.
Bits of misfolded proteins processed by specialty organelles may accumulate in the main compartment of the cell, the cytosol, where they can be tagged for disposal by the cellular garbage service.
Moreover, some scientists suggest, that the damage of the DNA and the corresponding with it «wrong proteins» is a main factor for the accumulation of «all the cellular gunk», and they suppose, that even after the removal of the «gunc», it will accumulate again if the DNA remains damaged.
He founded Gladstone's multi-pronged research program on Alzheimer's in 1998, and has since identified molecular and cellular processes by which amyloid - beta proteins, which accumulate in the brains of Alzheimer patients, impair cognitive functions.
Certain types of misfolded proteins defy eradication by the cellular protein degradation machinery and accumulate with age, causing cellular toxicity.
March 13, 2017 Parallel cellular pathways activate the process that controls organ growth A new study from the University of Chicago suggests that while proteins that control organ growth accumulate around the edges of cells, they actually function at a different cellular site.
When heavy metals accumulate in the body they can interrupt normal cellular processes by binding with protein sites and replacing the metals that naturally occur in the cell.
It accumulates within the cells, and reacts with cellular proteins such as enzymes and DNA.
When cellular proteins fold improperly and clump together, they accumulate and form the plaque that is involved in the pathogenesis of Alzheimer's and other brain diseases.