The conclusions, obtained by tracking thousands of mobile phone users, could help researchers devise more
accurate models of disease outbreaks.
Not exact matches
The highly
accurate reproduction
of disease pathology seen with these
models should advance the study
of these unusual but deadly
diseases.
The
model showed that regular and frequent testing
of cattle could eventually lead to the eradication
of the
disease, whether or not badgers were culled and despite the current test being at most 80 %
accurate.
While some seek to use iPSCs as replacements for cells compromised by
disease, the new Mount Sinai study sought to determine if they could serve as an
accurate model of genetic
disease «in a dish.»
The CRISPR - Cas technology is used to generate more
accurate genotypic
models of disease through precise genomic changes.
Researchers from the group
of Gary L. Dunbar at Central Michigan University, Michigan, USA have recently shown the ability
of adenovirally generated rat iPSCs to survive and differentiate in the striatum
of rats [6], and now in a study in Stem Cells Translational Medicine, they focus on the efficacy
of transplantation
of these cells into the 3 - nitropropionic acid (3 - NP) rat
model of HD [7], which induces cell death by energy - depleting mechanisms providing an
accurate model of cell loss and replicates many features
of the
disease [8].
As a result
of these findings, the team were able to conclude that the Drosophila
model was an effective and
accurate model of human kidney
disease.
She has discovered several novel
disease specific cellular phenotypes in their in vitro
models, many
of them involved in
accurate performance
of the neural progenitors.
Over the last few years, scientists have been able to recreate
accurate models of human organs by embedding living tissue onto chips, allowing them to study the effects
of drugs and
diseases without testing on animals or humans.
The first
accurate mouse
model of an aggressive childhood muscle cancer has improved researchers» understanding
of the cause
of the
disease and could accelerate the identification
of new...
Because
of the ease with which the CRISPR / Cas9 system can be applied, it has quickly become a robust tool for generating
accurate genetic
disease models in the laboratory and for identifying novel therapeutic targets in the clinic.
The use
of nonhuman primates to
model this
disease provides the most
accurate representation
of human Lyme
disease as demonstrated in this work.
Accurate models of mutation rate are also expected to inform
disease - gene discovery studies that rely on recurrent de novo mutations.