Sentences with phrase «acetyltransferase gcn5»

In addition, Vitamin D enhances the activity of the enzyme, choline acetyltransferase.

Protein stability assays demonstrated that in S Typhi the half - life of HilD, the dominant regulator of SPI - 1, is three times longer in the presence of bile; this increase in stability was independent of the acetyltransferase Pat.

To explore this potential, the present study investigated the neurotrophic effects of CTPB (N -(4 - chloro -3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide), which is a potent small molecule activator of the histone acetyltransferase p300 / CBP, in the SH - SY5Y neuronal cell line.

At sites of UV damage, E2F1 recruits the histone acetyltransferase GCN5, which acetylates histone H3K9 in order to open chromatin structure and increase accessibility to the damaged site by the DNA repair machinery.

Turnover and transformation of mitochondrial acetyl - CoA acetyltransferase into CoA - modified forms

Together, Myc and Gcn5, a histone acetyltransferase, reprogram fibroblasts to a stem cell state by activating an alternative splicing network.

A small molecule activator of p300 / CBP histone acetyltransferase promotes survival and neurite growth in a cellular model of Parkinson's Disease

Total neuron and length densities of tyrosine hydroxylase (TH), choline acetyltransferase (ChAT), and serotonin transporter (SERT)- immunoreactive axons in the frontal cortex (areas 4, 9, and 32) of humans, chimpanzees, and moor macaques.

The catalytic core of p300 shown here has a domain that acetylates chromatin (histone acetyltransferase or HAT) and a domain that recognizes the acetylation (bromodomain or Bd).

Total neuron and choline acetyltransferase - immunoreactive axon length densities for select regions within the striatum and globus pallidus.

Zhang X, Peng D, Xi Y, Yuan C, Sagum CA, Klein BJ, Tanaka K, Wen H, Kutateladze TG, Li W, Bedford MT, Shi X. (2016) G9a - mediated methylation of ERα links the PHF20 / MOF histone acetyltransferase complex to hormonal gene expression.

dCas9 fused to the catalytic domain of p300 acetyltransferase increases levels of H3K27ac histone modification at specified loci.

Deletion of choline acetyltransferase in enteric neurons results in postnatal intestinal dysmotility and dysbiosis — Carl D Johnson — The FASEB Journal

The lower level of spermine in the epileptic rat's brain was evidently caused by an upregulation of spermidine / spermine - N (1)- acetyltransferase.

The team identified three related genes encoding the enzyme, called glyphosate N - acetyltransferase (GAT).

Gcn5 is an enzyme known as a histone acetyltransferase which delivers molecular components making up an acetyl group to histone genes, allowing the genes to be switched on or off.

The responsiveness of the pineal β - adrenergic receptor that regulates serotonin - N - acetyltransferase activity is nearly ten times greater at the end of the light period (0600 to 1800 hours) than at the end of the dark period (1800 to 0600 hours).

Activators of histone acetyltransferases (HAT) provide an alternative approach for the selective activation of gene expression, however little is known about the potential of HAT activators as drug therapies for PD.

MYST histone acetyltransferases have crucial functions in transcription, replication and DNA repair and are hence implicated in development and cancer.