Sentences with phrase «achieve durable remissions»
Some dogs with T cell disease achieve durable remissions, and some patients with B cell disease do not.
https://cvm.ncsu.edu/ Not exact matches
Priority will be given to studies that evaluate combinations of agents that induce immune deviation and / or regulation, produce effector cell depletion or exhaustion, to achieve durable clinical remission of disease.
The other 5 vaccinated dogs that relapsed received single - agent prednisone as salvage therapy, one of which achieved a durable second remission and did not relapse.
Fifteen of 19 (79 %) vaccinated dogs in Group 2 eventually relapsed, but 4 dogs (21 %) did not and achieved a durable (> 16 months) first remission after chemotherapy and CD40 - B vaccination.
In the unvaccinated Group 3, 39 of 46 dogs (84 %) that relapsed were treated with salvage chemotherapy and one dog received prednisone alone; however, only 3 (7.7 %) of the dogs in Group 3 that received salvage therapy achieved a durable second remission, compared to 40 % of vaccinated dogs that achieved a durable second remission to salvage therapy, a difference that was statistically significant (p = 0.025).
Ten of the 15 vaccinated dogs (66.7 %) in Group 2 that relapsed were treated with cyclophosphamide, vincristine, and prednisone (COP) as salvage therapy and four of these dogs (40 %) achieved durable second clinical remission (> 22 months) and did not relapse.