Secondary rounds of tumor sequencing — possible now that the cost has fallen dramatically — could point to new mutations
acquired by their cancer cells, thus suggesting further treatments.
Not exact matches
Seeking one mechanism to explain the induction of
cancer by many different agents, Huebner and Todaro had suggested that retrovirus oncogenes are a part of the genetic baggage of all
cells, perhaps
acquired through viral infection early in evolution.
«A general message from these studies is that
cancer cells benefit from modulating epigenetic factors like SIRT6
by acquiring the ability to override normal cellular growth control patterns,» says Mostoslavsky, an associate professor of Medicine at Harvard Medical School and an associate member at the Broad Institute.
Because
cancer cells acquire mutations in oncogenes — genes that can transform
cells into
cancer cells — to support their growth and survival, a great deal of research has focused on identifying oncogenes that could be targeted
by cancer drugs.
Each MPN is a different condition, but they are thought to be caused
by an abnormal
cancer stem
cell that may have
acquired genetic mutations that make it unable to produce blood
cells normally
The microbial host defense can be weakened
by secondary or
acquired diseases (injury, endocrinopathy,
cancer or co-infection) or primary inherited disorders that affect the barriers that keep infection out or functions of white blood
cells.