Antibiotics that target mitochondria effectively eradicate cancer stem cells,
across multiple tumor types: treating cancer like an infectious disease.
«Opdivo has become a foundational treatment that is transforming cancer care
across multiple tumor types,» chief executive Giovanni Caforio said in a statement.
Not exact matches
Both Tsigelny and Kurzrock agreed that this finding is an excellent example of the power of collaboration between SDSC and the Moores Cancer Center, and that such modeling needed to be studied
across tumors and with
multiple different genes involved in cancer.
«We're looking for
multiple mutations
across tumors, mutations that turn on genes and promote cell growth,» Dias - Santagata says.
However, about 10 percent of them are common
across multiple cancers, suggesting that a relatively small number of therapies targeting these core dependencies might each hold promise for combatting several
tumors.
Although we believe our approaches have broad potential
across multiple therapeutic areas, we are focused in oncology and have engineered our technologies to activate the immune system's natural ability to create
tumor - specific cytotoxic T cells, or CTLs, to fight cancer.
Understanding how
tumor cells sabotage the body's immune defenses stems from the collective work of many scientists over many years and
across multiple institutions.
By assessing the incidence of a particular mutation or the frequency at which certain genes / pathways are altered
across multiple patients (of the same
tumor type), it should be possible to identify key mutations.