Sentences with phrase «act as antibodies»

Not exact matches

Gladney notes that during the first six months of life, the baby's own immune system is so immature that antibodies in mom's milk act as a powerful extension of it.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

The researchers first stumbled onto this while studying how mouse antibodies act as catalysts.

In this case, AAV acts as a Trojan horse and leads epithelial cells in the airways to make the antibodies; the question is how long they will continue doing so.

They show that highly purified NS1 acts as a pathogen - associated molecular pattern (PAMP) that activates mouse macrophages and human peripheral blood mononuclear cells (PBMCs) in culture via TLR4, resulting in release of inflammatory cytokines — an effect that was blocked by either a TLR4 antagonist or an anti-TLR4 antibody.

Alphamers (purple) act as homing beacons, attracting pre-existing anti-alpha-Gal antibodies (green) to the bacterial surface.

Some act as guard dogs that raise the alarm when they detect invading viruses; others kill virus - infected cells directly, or help B cells to produce antibodies.

His work also suggests that therapies designed to block immune checkpoints, such as anti-PD-1 antibodies, may act in part by shifting this metabolic competition back in favor of immune cells.

However, ADCs that use derivatives of calicheamicin, which promotes double - stranded DNA breaks, such as GO and inotuzumab ozogamicin, 40,41 have limited activity in cells with high multidrug resistance protein activity, a phenotype found in a significant fraction of AML patients.42 Another ADC, SGN - CD123A, comprising an engineered form of the CD123 - targeting 7G3 antibody conjugated to a synthetic pyrrolobenzodiazepine dimer, which acts via DNA crosslinking, has entered clinical trials after showing robust activity in preclinical models of AML, including those with multidrug resistance.33

I'm liking the ELISA / ACT test as well coz it's not just antibodies, it's looking at various lymphocytes, too.

Just as certain disease - causing agents or foreign substances will cause the body to produce antibodies against them, certain proteins are known to act like antigens in celiac disease patients, causing the body to produce antibodies against them.

And then there's the fact that the lymphatic system acts as a sort of microbiological conveyor belt — fundamentally useful when antibodies can be released in a timely and efficient fashion to dispatch any antigens, but highly problematic when the system is overwhelmed or overrun.

WGA can act as an adjuvant, causing the body to generate antibodies against proteins that, in isolation, the body would not form antibodies against.

The immune system is made up of a team of different types of cells that, while each having their own specific function, work together to protect the body from foreign invaders: B - cells produce antibodies; T - cells conduct surveillance for potentially dangerous molecules and kills dangerous cells such as disease - causing bacteria; and macrophages are the scavenger cells of your body acting like garbage trucks, cleaning up residue and removing potentially dangerous substances.