Sentences with phrase «activate immune attack»

Not exact matches

When the dendritic cells are activated, they train T cells — their allies in the adaptive arm of the immune system — to attack cancer cells anywhere in the body, whether at the site of the original tumor or distant metastases.

A tangle of virus and antibodies in their lungs activated an immune system component called complement, which failed to clear the mess and instead attacked lung tissue.

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving.

The researchers studied two types of cells called effector T cells, which activate the immune system to defend our body against different pathogens, and regulatory T cells, which help control the immune system and prevent it from attacking healthy parts of its environment.

Two key experiments demonstrated this necessary and sufficient role for the activated T - cells, which presumably attack heart muscle tissue in an auto - immune fashion.

When the immune system is activated, it produces antibodies that attack a particular enzyme in the body.

First, the immune system develops antibodies that attack the body's own DNA, then that activated immune system attacks the kidneys,» Mohan said.

A higher temperature was better at eliminating primary tumors that were heat treated, but did not activate the immune system as well to find and attack metastatic tumors.

Orchestrating a successful immune attack against tumors has proven difficult so far, but a new study from MIT suggests that such therapies could be improved by simultaneously activating both arms of the immune system.

Until now, most researchers have focused on one of two strategies: attacking tumors with antibodies, which activate the innate immune system, or stimulating T cells, which form the backbone of the adaptive immune system.

CD74 is broken into products that fit into the groove of cell surface immune response proteins as part of the chain of events that activates T cells — immune cells that normally attack infected (or damaged) cells in the body.

«Nuclear DNA gets cut, activates immune system to attack cancer cells.»

Antibodies stimulate the recruitment of additional immune cells that help to activate T cells; the vaccine stimulates proliferation of T cells that can attack the tumor; IL - 2 helps the T cell population to expand quickly; and the anti-PD1 molecule helps T cells stay active longer.

In the new study, the researchers used a combination of four different therapies to activate both of the immune system's two branches, producing a coordinated attack that led to the complete disappearance of large, aggressive tumors in mice.

The immunotherapy is designed to activate the disease - fighting immune system to attack and kill tumor cells.

Some scientists suspect that immune cells activated by the foreign organ but lacking the CD154 signal die soon after a transplant, although it's not clear why new generations of immune cells wouldn't recognize and attack the tissue.

Giving patients a dose of their tumor neoantigens, which look foreign to the immune system, should help activate immune cells called T cells to attack the cancer cells.

They then demonstrated that antibodies to MSP3 activate the immune system's cell - killing machinery, which can attack and kill the parasite.

But this defense system can also be inappropriately activated and attack cells, contributing to a broad spectrum of immune, inflammatory, and age - related diseases.

To combat the nation's third deadliest cancer, the phase 1b / 2 open - label study will explore the combination of standard chemotherapy and two immunotherapy agents: an anti-PD-1 checkpoint inhibitor and a novel antibody targeting CD40, a protein that when activated can drive the immune system to attack tumors.

Whereas when an effector is detected inside the plant cell, the plant knows for sure it is being attacked and it activates ETI, a very strong immune response,» said co-author Greg Martin, the Boyce Schulze Downey Professor at BTI.

In the new field of immunotherapy, for example, we want to use molecules to bind to the surface of an immune cell and activate that cell so it attacks cancer.

Increases levels of properdin, a chemical that activates part of the immune system responsible for increasing defence mechanisms against viral and bacterial attacks.

Subsequent lab tests revealed that this immune response had been activated specifically to attack the mother's cells.

[Phosphate] destroys the lipid layer of the skin; [fragrances and dyes] activate the T cell arm of the immune system, which can mistakenly attack normal cells.»

The immune system is responsible for protecting the body from various foreign viruses and bacteria, but an asthmatics» immune system perceives certain substances and allergens as big threats and activates an exaggerated response, thus triggering an asthma attack.

The macrophages release cytokines that can activate more innate immune cells, readying them for attack on viruses or cancer cells, or they can activate the adaptive arm of immunity, priming it for clonal expansion.

Many healthcare practitioners report there is frequently a hidden infection that either precedes or seems to trigger an initial autoimmune attack, or subsequently appears when the immune system is weakened once autoimmunity is activated.

When the immune system activates in order to attack newly ingested pathogens it is using up its energy reserves that could be used for other activities.

By combining the beta - glucuronidase enzyme with Lyme antigens, the LDI diminishes the abnormally activated TH2 immune system, which is the major cause of symptoms in chronic Lyme disease, but allows the TH1 to take over and effectively attack the Lyme bacteria in the cells.

APS (also known as astragalus polysaccharide) has been shown to activate the immune system by enhancing the transformation of T lymphocytes (a sub-type of white blood cells, crucial in the regulation of immune responses), as well as the activation of B lymphocytes (which produce antibodies that are used to attack invading bacteria, viruses, and toxins) and dendritic cells, which trigger immune reactions to toxins.

This also affects thyroid health since a suppressed immune system can activate viruses capable of attacking and damaging the thyroid.

Stress - activated cortisol bombards the memory center, killing nerve cells in the hippocampus, and attacks the immune system, which often causes depression and anxiety.

Purpose of Study: We have been evaluating ways to activate the immune system into recognizing that a tumor is foreign and attacking it.

Purpose of Study: The purpose of this study was to develop better methods to treat advanced cancer, specifically to find ways to activate the immune system to attack cancer.

Fever increases the body's set temperature (range of temperature in which body systems can function normally) to assist the immune system by activating immune cells to attack the foreign invader, such as a bacterial infection.